Frequency-modulated pulses of ERK activity transmit quantitative proliferation signals. - Wikidata - awgldk - TriplyDB

Frequency-modulated pulses of ERK activity transmit quantitative proliferation signals.

Frequency-modulated pulses of ERK activity transmit quantitative proliferation signals.

http://www.wikidata.org/entity/Q30586789

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The regulation of oncogenic Ras/ERK signalling by dual-specificity mitogen activated protein kinase phosphatases (MKPs)Intra-tumor heterogeneity of cancer cells and its implications for cancer treatment Extracellular signal-regulated kinases 1/2 as regulators of cardiac hypertrophy Spatial and temporal organization of signaling pathways Combinatorial gene regulation by modulation of relative pulse timing.Akt signaling dynamics in individual cells.Reversible interconversion and maintenance of mammary epithelial cell characteristics by the ligand-regulated EGFR system.Accurate encoding and decoding by single cells: amplitude versus frequency modulation Transporting Cells in Semi-Solid Gel Condition and at Ambient Temperature Pulsatile dynamics in the yeast proteome.Data-driven modeling reconciles kinetics of ERK phosphorylation, localization, and activity states.NF-κB signalling and cell fate decisions in response to a short pulse of tumour necrosis factor.Relaxation oscillations and hierarchy of feedbacks in MAPK signaling Optogenetic perturbation and bioluminescence imaging to analyze cell-to-cell transfer of oscillatory information.Excitability in the p53 network mediates robust signaling with tunable activation thresholds in single cells 'Particle genetics': treating every cell as unique.Loss of regulator of G protein signaling 5 promotes airway hyperresponsiveness in the absence of allergic inflammation.Spatio-temporally precise activation of engineered receptor tyrosine kinases by light.Ultradian oscillations and pulses: coordinating cellular responses and cell fate decisions Using optogenetics to interrogate the dynamic control of signal transmission by the Ras/Erk module.Optical control of cell signaling by single-chain photoswitchable kinases Single-cell mass cytometry of TCR signaling: amplification of small initial differences results in low ERK activation in NOD mice Temporal decoding of MAP kinase and CREB phosphorylation by selective immediate early gene expression Determinants of cell-to-cell variability in protein kinase signaling.Intercellular propagation of extracellular signal-regulated kinase activation revealed by in vivo imaging of mouse skin.Computational analysis of signaling patterns in single cells.Physiological epidermal growth factor concentrations activate high affinity receptors to elicit calcium oscillations.Measuring and sorting cell populations expressing isospectral fluorescent proteins with different fluorescence lifetimes.Quantitative analysis of receptor tyrosine kinase-effector coupling at functionally relevant stimulus levels.Multiscale analysis of the murine intestine for modeling human diseases.Limits on information transduction through amplitude and frequency regulation of transcription factor activity Conditional robustness analysis for fragility discovery and target identification in biochemical networks and in cancer systems biology.Intracellular Information Processing through Encoding and Decoding of Dynamic Signaling Features.MAPK feedback encodes a switch and timer for tunable stress adaptation in yeast.Optimizing Population Variability to Maximize Benefit.Dynamic Modeling and Analysis of the Cross-Talk between Insulin/AKT and MAPK/ERK Signaling Pathways.Preclinical assessments of the MEK inhibitor PD-0325901 in a mouse model of Neurofibromatosis type 1.Effects of AKT inhibition on HGF-mediated erlotinib resistance in non-small cell lung cancer cell lines Noncommutative Biology: Sequential Regulation of Complex Networks.Processing Oscillatory Signals by Incoherent Feedforward Loops.

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P2860

Frequency-modulated pulses of ERK activity transmit quantitative proliferation signals.

http://www.wikidata.org/entity/Q30586789

description

2012 nî lūn-bûn

@nan

2012 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Frequency-modulated pulses of ERK activity transmit quantitative proliferation signals.

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Frequency-modulated pulses of ERK activity transmit quantitative proliferation signals.

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type

label

Frequency-modulated pulses of ERK activity transmit quantitative proliferation signals.

@ast

Frequency-modulated pulses of ERK activity transmit quantitative proliferation signals.

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prefLabel

Frequency-modulated pulses of ERK activity transmit quantitative proliferation signals.

@ast

Frequency-modulated pulses of ERK activity transmit quantitative proliferation signals.

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J.MOLCEL.2012.11.002

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Frequency-modulated pulses of ERK activity transmit quantitative proliferation signals.

@en

P2093

Gordon B Mills

http://www.w3.org/2001/XMLSchema#string

Joan S Brugge

http://www.w3.org/2001/XMLSchema#string

John G Albeck

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P2860

Reduced MAP kinase phosphatase-1 degradation after p42/p44MAPK-dependent phosphorylation

Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS

Extracellular signal-regulated kinases phosphorylate mitogen-activated protein kinase phosphatase 3/DUSP6 at serines 159 and 197, two sites critical for its proteasomal degradation

Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma

The selectivity of protein kinase inhibitors: a further update

Signaling switches and bistability arising from multisite phosphorylation in protein kinase cascades

Modeling T cell antigen discrimination based on feedback control of digital ERK responses

CellProfiler: free, versatile software for automated biological image analysis

Linear approaches to intramolecular Förster resonance energy transfer probe measurements for quantitative modeling

Growth factor-induced MAPK network topology shapes Erk response determining PC-12 cell fate

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249-261

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10.1016/J.MOLCEL.2012.11.002

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2

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49

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2012-12-06T00:00:00Z

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23219535

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