Aneuploidy vs. gene mutation hypothesis of cancer: recent study claims mutation but is found to support aneuploidy.
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The role of chromosomal instability in tumor initiation.Genomic Changes in Normal Breast Tissue in Women at Normal Risk or at High Risk for Breast CancerTissue Regeneration in the Chronically Inflamed Tumor Environment: Implications for Cell Fusion Driven Tumor Progression and Therapy Resistant Tumor Hybrid CellsDo mutator mutations fuel tumorigenesis?Molecular mechanism underlying lymphatic metastasis in pancreatic cancerAneuploid colon cancer cells have a robust spindle checkpointEstrogen mediates Aurora-A overexpression, centrosome amplification, chromosomal instability, and breast cancer in female ACI ratsCytokinesis failure due to derailed integrin traffic induces aneuploidy and oncogenic transformation in vitro and in vivo.Whole chromosome gain does not in itself confer cancer-like chromosomal instabilityKaryotypic evolutions of cancer species in rats during the long latent periods after injection of nitrosourea.A role for polyploidy in the tumorigenicity of Pim-1-expressing human prostate and mammary epithelial cells.Human cancers express mutator phenotypes: origin, consequences and targeting.The gene-reduction effect of chromosomal losses detected in gastric cancers.The fate of chrysotile-induced multipolar mitosis and aneuploid population in cultured lung cancer cells.Auto-catalysed progression of aneuploidy explains the Hayflick limit of cultured cells, carcinogen-induced tumours in mice, and the age distribution of human cancerOrigin of multidrug resistance in cells with and without multidrug resistance genes: chromosome reassortments catalyzed by aneuploidy.Specific aneusomies in Chinese hamster cells at different stages of neoplastic transformation, initiated by nitrosomethylurea.Multiple centrosomes arise from tetraploidy checkpoint failure and mitotic centrosome clusters in p53 and RB pocket protein-compromised cells.Impaired CK1 delta activity attenuates SV40-induced cellular transformation in vitro and mouse mammary carcinogenesis in vivoPolyploidy-induction by dihydroxylated monochlorobiphenyls: structure-activity-relationshipsOrigin of metastases: subspecies of cancers generated by intrinsic karyotypic variations.Karyotypic determinants of chromosome instability in aneuploid budding yeast.A comprehensive continuous-time model for the appearance of CGH signal due to chromosomal missegregations during mitosis.Activated oncogenes promote and cooperate with chromosomal instability for neoplastic transformation.Centrosome amplification and the development of cancer.Co-cultivation of murine BMDCs with 67NR mouse mammary carcinoma cells give rise to highly drug resistant cellsFunctional inactivation of pRB results in aneuploid mammalian cells after release from a mitotic block.Transcriptional Dynamics of Immortalized Human Mesenchymal Stem Cells during Transformation.Genetic and biological subgroups of low-stage follicular thyroid cancerCell Fusion Connects Oncogenesis with Tumor Evolution.Scientific and clinical opportunities for modeling blood disorders with embryonic stem cellsInduction of aneuploidy by increasing chromosomal instability during dedifferentiation of hepatocellular carcinoma.Perspective on mutagenesis and repair: the standard model and alternate modes of mutagenesis.The Genome Health Clinic and Genome Health Nutrigenomics concepts: diagnosis and nutritional treatment of genome and epigenome damage on an individual basis.Karyotype alteration generates the neoplastic phenotypes of SV40-infected human and rodent cellsDelayed Numerical Chromosome Aberrations in Human Fibroblasts by Low Dose of Radiation.Immortality of cancers: a consequence of inherent karyotypic variations and selections for autonomy.Selective pressures for and against genetic instability in cancer: a time-dependent problem.Refractory nature of normal human diploid fibroblasts with respect to oncogene-mediated transformation.Promoter methylation in the genesis of gastrointestinal cancer.
P2860
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P2860
Aneuploidy vs. gene mutation hypothesis of cancer: recent study claims mutation but is found to support aneuploidy.
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2000 nî lūn-bûn
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2000年の論文
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Aneuploidy vs. gene mutation h ...... s found to support aneuploidy.
@ast
Aneuploidy vs. gene mutation h ...... s found to support aneuploidy.
@en
type
label
Aneuploidy vs. gene mutation h ...... s found to support aneuploidy.
@ast
Aneuploidy vs. gene mutation h ...... s found to support aneuploidy.
@en
prefLabel
Aneuploidy vs. gene mutation h ...... s found to support aneuploidy.
@ast
Aneuploidy vs. gene mutation h ...... s found to support aneuploidy.
@en
P2093
P2860
P356
P1476
Aneuploidy vs. gene mutation h ...... s found to support aneuploidy.
@en
P2093
P2860
P304
P356
10.1073/PNAS.97.7.3236
P407
P577
2000-03-01T00:00:00Z