Selective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodents.
about
Endocannabinoid signaling in social functioning: an RDoC perspectiveTask-specific enhancement of hippocampus-dependent learning in mice deficient in monoacylglycerol lipase, the major hydrolyzing enzyme of the endocannabinoid 2-arachidonoylglycerolSynthesis and Preclinical Evaluation of Sulfonamido-based [(11)C-Carbonyl]-Carbamates and Ureas for Imaging Monoacylglycerol Lipase.The Ratio of 2-AG to Its Isomer 1-AG as an Intrinsic Fine Tuning Mechanism of CB1 Receptor Activation.The Lid Domain in Lipases: Structural and Functional Determinant of Enzymatic Properties.Monoglyceride lipase: Structure and inhibitors.Chemical Genetic Approaches for the Investigation of Neutral Lipid Metabolism.Therapeutic effects of cannabinoids in animal models of seizures, epilepsy, epileptogenesis, and epilepsy-related neuroprotection.Monoglyceride lipase as a drug target: At the crossroads of arachidonic acid metabolism and endocannabinoid signaling.Molecular Imaging of Hydrolytic Enzymes Using PET and SPECT.Free-energy studies reveal a possible mechanism for oxidation-dependent inhibition of MGL.Stress-Induced Chronic Visceral Pain of Gastrointestinal Origin.The selective reversible FAAH inhibitor, SSR411298, restores the development of maladaptive behaviors to acute and chronic stress in rodents.In Vitro and in Vivo Evaluation of 11C-Labeled Azetidinecarboxylates for Imaging Monoacylglycerol Lipase by PET Imaging Studies.Therapeutic endocannabinoid augmentation for mood and anxiety disorders: comparative profiling of FAAH, MAGL and dual inhibitors.The crystal structure of monoacylglycerol lipase from M. tuberculosis reveals the basis for specific inhibition.
P2860
Q28067103-562C3F9F-B1C5-40DE-AE6E-F1F70BB7E965Q35672120-AE9C1624-A4F2-4E76-A299-A1D9854907EAQ36970368-FCCCA591-C59A-44B1-B499-926FE18A2885Q37651666-66D25275-04D6-45A4-830D-57878B6CCEC5Q37689451-5648AB5E-1550-48EE-A4E2-B08A0EDF08C4Q38555486-9E244A74-1E4E-45E6-B5E2-F4D00A5513EFQ38682493-A6BC0544-EE64-4E89-B586-1E42DEAE3B47Q38758364-D16B047C-7EC2-48C2-9893-F43509ED91CAQ39141240-6A125476-9480-4362-8CC3-9A0D6A934002Q41862863-3539240C-6AE3-435D-9554-A2BE66AA45C1Q42375607-4529EEB9-8E8C-48BA-8A31-01A9029D0702Q47171305-5C64C8AF-BB74-478D-B063-8006BE5F050CQ48512439-97C50112-A6D9-49F2-B7BB-B2754937EB7BQ52315796-4FBCE260-ECFE-40E2-839F-1719664F3D43Q53401817-7D0DDE27-6980-4E85-9F44-AC2E96ABA420Q55312142-3080EF29-18B7-4B13-8630-77DBDEAE02AC
P2860
Selective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodents.
description
2015 nî lūn-bûn
@nan
2015 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Selective blockade of the hydr ...... ciceptive activity in rodents.
@ast
Selective blockade of the hydr ...... ciceptive activity in rodents.
@en
type
label
Selective blockade of the hydr ...... ciceptive activity in rodents.
@ast
Selective blockade of the hydr ...... ciceptive activity in rodents.
@en
prefLabel
Selective blockade of the hydr ...... ciceptive activity in rodents.
@ast
Selective blockade of the hydr ...... ciceptive activity in rodents.
@en
P2093
P2860
P356
P1433
P1476
Selective blockade of the hydr ...... ciceptive activity in rodents.
@en
P2093
Agnès Jacquet
Alexey Rak
Bailin Zhang
Dmitri Wiederschain
Dominique Françon
Fangxian Sun
Franck Augé
François Vallée
Guy Griebel
Heike Arlt
P2860
P2888
P356
10.1038/SREP07642
P407
P577
2015-01-06T00:00:00Z
P5875
P6179
1046602066