Galectin-1 drives pancreatic carcinogenesis through stroma remodeling and Hedgehog signaling activation. - Wikidata - awgldk - TriplyDB

Galectin-1 drives pancreatic carcinogenesis through stroma remodeling and Hedgehog signaling activation.

Galectin-1 drives pancreatic carcinogenesis through stroma remodeling and Hedgehog signaling activation.

http://www.wikidata.org/entity/Q30620697

about

Regulatory role of glycans in the control of hypoxia-driven angiogenesis and sensitivity to anti-angiogenic treatment Discriminating patients with early-stage pancreatic cancer or chronic pancreatitis using serum electrospray mass profiling A Novel Galectin-1 Inhibitor Discovered through One-Bead Two-Compound Library Potentiates the Antitumor Effects of Paclitaxel in vivo.Spectral library-based glycopeptide analysis-detection of circulating galectin-3 binding protein in pancreatic cancer.Galectin-1 induces hepatocellular carcinoma EMT and sorafenib resistance by activating FAK/PI3K/AKT signaling.Identification of galectin-1 as a novel mediator for chemoresistance in chronic myeloid leukemia cells.Galectin-1 from cancer-associated fibroblasts induces epithelial-mesenchymal transition through β1 integrin-mediated upregulation of Gli1 in gastric cancer.Pancreatic cancer: from bench to bedside.Galectin-1 induces invasion and the epithelial-mesenchymal transition in human gastric cancer cells via non-canonical activation of the hedgehog signaling pathway.The conflicting roles of tumor stroma in pancreatic cancer and their contribution to the failure of clinical trials: a systematic review and critical appraisal.Immune Therapy in GI Malignancies: A Review.Re-wiring regulatory cell networks in immunity by galectin-glycan interactions.Seed-in-Soil: Pancreatic Cancer Influenced by Tumor Microenvironment.Pancreatic cancer stroma: controversies and current insights.Proteomic strategies in the search for novel pancreatic cancer biomarkers and drug targets: recent advances and clinical impact.Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance.Cancer Manipulation of Host Physiology: Lessons from Pancreatic Cancer.The pancreatic niche inhibits the effectiveness of sunitinib treatment of pancreatic cancer.TAp73 loss favors Smad-independent TGF-β signaling that drives EMT in pancreatic ductal adenocarcinoma.Contribution of galectin-1, a glycan-binding protein, to gastrointestinal tumor progression.Galectin-1 is a diagnostic marker involved in thyroid cancer progression.Targeting Galectin-1 in pancreatic cancer: immune surveillance on guard.Yes-associated protein and immunosuppressive microenvironment in pancreatic cancer development: a new strategy to improve immunotherapy efficacy?PSC-derived Galectin-1 inducing epithelial-mesenchymal transition of pancreatic ductal adenocarcinoma cells by activating the NF-κB pathway.Functions of pancreatic stellate cell-derived soluble factors in the microenvironment of pancreatic ductal carcinoma.The peripheral immune status of granulocytic myeloid-derived suppressor cells correlates the survival in advanced gastric cancer patients receiving cisplatin-based chemotherapy.Immune Evasion in Pancreatic Cancer: From Mechanisms to Therapy.Galectin-1 Inhibitor OTX008 Induces Tumor Vessel Normalization and Tumor Growth Inhibition in Human Head and Neck Squamous Cell Carcinoma Models.Galectin-1: A Jack-of-All-Trades in the Resolution of Acute and Chronic Inflammation.Targeting galectin-1 inhibits pancreatic cancer progression by modulating tumor-stroma crosstalk.Galectins in Intestinal Inflammation: Galectin-1 Expression Delineates Response to Treatment in Celiac Disease Patients.Immunotherapy in Gastrointestinal Cancers.Immune-Mediated and Hypoxia-Regulated Programs: Accomplices in Resistance to Anti-angiogenic Therapies.The Extracellular Matrix and Pancreatic Cancer: A Complex Relationship Targeting Galectin-1 Impairs Castration-Resistant Prostate Cancer Progression and Invasion Increased plasma levels of galectin-1 in pancreatic cancer: potential use as biomarker

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P2860

Galectin-1 drives pancreatic carcinogenesis through stroma remodeling and Hedgehog signaling activation.

http://www.wikidata.org/entity/Q30620697

description

2014 nî lūn-bûn

@nan

2014 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի մայիսին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

@wuu

name

Galectin-1 drives pancreatic c ...... Hedgehog signaling activation.

@ast

Galectin-1 drives pancreatic c ...... Hedgehog signaling activation.

@en

type

label

Galectin-1 drives pancreatic c ...... Hedgehog signaling activation.

@ast

Galectin-1 drives pancreatic c ...... Hedgehog signaling activation.

@en

prefLabel

Galectin-1 drives pancreatic c ...... Hedgehog signaling activation.

@ast

Galectin-1 drives pancreatic c ...... Hedgehog signaling activation.

@en

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0008-5472.CAN-13-3013

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Cancer Research

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Galectin-1 drives pancreatic c ...... Hedgehog signaling activation.

@en

P2093

Carolina Navas

http://www.w3.org/2001/XMLSchema#string

Elena Ortiz-Zapater

http://www.w3.org/2001/XMLSchema#string

Françoise Poirier

http://www.w3.org/2001/XMLSchema#string

Jessica Munné-Collado

http://www.w3.org/2001/XMLSchema#string

Maite G Fernández-Barrena

http://www.w3.org/2001/XMLSchema#string

Mar Iglesias

http://www.w3.org/2001/XMLSchema#string

Martin E Fernández-Zapico

http://www.w3.org/2001/XMLSchema#string

Mireia Moreno

http://www.w3.org/2001/XMLSchema#string

Rosa F Hwang

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P2860

A binding site for Gli proteins is essential for HNF-3beta floor plate enhancer activity in transgenics and can respond to Shh in vitro

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

Pancreatic ductal cells in development, regeneration, and neoplasia

The pancreas cancer microenvironment

Cancer statistics, 2013

Gene expression profiling leads to identification of GLI1-binding elements in target genes and a role for multiple downstream pathways in GLI1-induced cell transformation

Dispatched, a novel sterol-sensing domain protein dedicated to the release of cholesterol-modified hedgehog from signaling cells

Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma

P304

3512-3524

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scholarly article

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10.1158/0008-5472.CAN-13-3013

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P433

13

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P478

74

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Hans-Joachim Gabius

Neus Martínez-Bosch

P577

2014-05-08T00:00:00Z

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262189216

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24812270

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4332591

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