A synaptic basis for paracrine interleukin-2 signaling during homotypic T cell interaction
about
Interleukin-2 receptor signaling: at the interface between tolerance and immunitySecondary T cell–T cell synaptic interactions drive the differentiation of protective CD8+ T cellsVirological synapse-mediated spread of human immunodeficiency virus type 1 between T cells is sensitive to entry inhibitionImmature T-cell clustering and efficient differentiation require the polarity protein Scribble.Regulatory T cells suppress the late phase of the immune response in lymph nodes through P-selectin glycoprotein ligand-1.A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors.Functions of the FAK family kinases in T cells: beyond actin cytoskeletal rearrangement.CD4+ T-cell synapses involve multiple distinct stages.Regulation of T cell priming by lymphoid stroma.NK cells detect changes in adaptive immunity within mouse decidua from gestation day eight.Balancing speed and accuracy of polyclonal T cell activation: a role for extracellular feedback.Homotypic NK cell-to-cell communication controls cytokine responsiveness of innate immune NK cellsBeyond regulatory T cells: the potential role for IL-2 to deplete T-follicular helper cells and treat autoimmune diseases.The dendritic cell cytoskeleton promotes T cell adhesion and activation by constraining ICAM-1 mobilityThe tetraspanin CD53 modulates responses from activating NK cell receptors, promoting LFA-1 activation and dampening NK cell effector functions.An artificial antigen-presenting cell with paracrine delivery of IL-2 impacts the magnitude and direction of the T cell response.Three-Dimensional Gradients of Cytokine Signaling between T Cells.PDE/ODE modeling and simulation to determine the role of diffusion in long-term and -range cellular signaling.Activation of the Hippo pathway by CTLA-4 regulates the expression of Blimp-1 in the CD8+ T cell.Memory T cell-driven differentiation of naive cells impairs adoptive immunotherapy.ICAM-1-dependent tuning of memory CD8 T-cell responses following acute infection.The great balancing act: regulation and fate of antiviral T-cell interactionsICAM-1-dependent homotypic aggregates regulate CD8 T cell effector function and differentiation during T cell activation.Control of T helper cell differentiation through cytokine receptor inclusion in the immunological synapse.Three-dimensional localization of T-cell receptors in relation to microvilli using a combination of superresolution microscopies.The cellular context of T cell signaling.Multi-cellular natural killer (NK) cell clusters enhance NK cell activation through localizing IL-2 within the cluster.T cell polarization at the virological synapse.Microspectroscopy reveals mechanisms of lymphocyte activation.Evolving immune circuits are generated by flexible, motile, and sequential immunological synapses.Mechanisms of enhanced HIV spread through T-cell virological synapses.Dynamic single-cell measurements of gene expression in primary lymphocytes: challenges, tools and prospects.Regulatory T-cell homeostasis: steady-state maintenance and modulation during inflammation.Control of Regulatory T Cell Migration, Function, and HomeostasisA Tunable Diffusion-Consumption Mechanism of Cytokine Propagation Enables Plasticity in Cell-to-Cell Communication in the Immune System.T cell migration, search strategies and mechanisms.Defective quorum sensing of acute lymphoblastic leukemic cells: evidence of collective behavior of leukemic populations as semi-autonomous aberrant ecosystems.Adequate immune response ensured by binary IL-2 and graded CD25 expression in a murine transfer model.LFA-1 antagonism inhibits early infiltration of endogenous memory CD8 T cells into cardiac allografts and donor-reactive T cell priming.IL-4 enhances IL-10 production in Th1 cells: implications for Th1 and Th2 regulation.
P2860
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P2860
A synaptic basis for paracrine interleukin-2 signaling during homotypic T cell interaction
description
2008 nî lūn-bûn
@nan
2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
A synaptic basis for paracrine ...... g homotypic T cell interaction
@ast
A synaptic basis for paracrine ...... g homotypic T cell interaction
@en
type
label
A synaptic basis for paracrine ...... g homotypic T cell interaction
@ast
A synaptic basis for paracrine ...... g homotypic T cell interaction
@en
prefLabel
A synaptic basis for paracrine ...... g homotypic T cell interaction
@ast
A synaptic basis for paracrine ...... g homotypic T cell interaction
@en
P2093
P2860
P1433
P1476
A synaptic basis for paracrine ...... g homotypic T cell interaction
@en
P2093
Aaron J Tooley
Catherine A Sabatos
Junsang Doh
Matthew F Krummel
Priya G Pandurangi
Rachel S Friedman
Sumone Chakravarti
P2860
P304
P356
10.1016/J.IMMUNI.2008.05.017
P407
P577
2008-07-31T00:00:00Z