A novel human gene similar to the protein kinase (PK) coding domain of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) codes for a serine-threonine PK and is expressed in melanoma cells.

A novel human gene similar to the protein kinase (PK) coding domain of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) codes for a serine-threonine PK and is expressed in melanoma cells.

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http://www.wikidata.org/entity/Q30655101

Q30655101

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A novel p53-inducible apoptogenic gene, PRG3, encodes a homologue of the apoptosis-inducing factor (AIF)The human genome encodes 10 alpha-crystallin-related small heat shock proteins: HspB1-10 HSP22, a new member of the small heat shock protein superfamily, interacts with mimic of phosphorylated HSP27 ((3D)HSP27)Molecular and cellular basis of viable dysfunctional myocardium.Gene program for cardiac cell survival induced by transient ischemia in conscious pigs.The Gln32Lys polymorphism in HSP22 of Zhikong scallop Chlamys farreri is associated with heat tolerance.Preemptive conditioning of the swine heart by H11 kinase/Hsp22 provides cardiac protection through inducible nitric oxide synthase.The Levels of H11/HspB8 DNA methylation in human melanoma tissues and xenografts are a critical molecular marker for 5-Aza-2'-deoxycytidine therapy.H11 kinase/heat shock protein 22 deletion impairs both nuclear and mitochondrial functions of STAT3 and accelerates the transition into heart failure on cardiac overload Restored expression of the atypical heat shock protein H11/HspB8 inhibits the growth of genetically diverse melanoma tumors through activation of novel TAK1-dependent death pathways.Induction of Hsp22 (HspB8) by estrogen and the metalloestrogen cadmium in estrogen receptor-positive breast cancer cells.Small heat shock proteins in inherited peripheral neuropathies.H11/HspB8 and Its Herpes Simplex Virus Type 2 Homologue ICP10PK Share Functions That Regulate Cell Life/Death Decisions and Human Disease Pharmacoinformatic and molecular docking studies reveal potential novel antidepressants against neurodegenerative disorders by targeting HSPB8.H11/HSPB8 Restricts HIV-2 Vpx to Restore the Anti-Viral Activity of SAMHD1.The sperm outer dense fiber protein is the 10th member of the superfamily of mammalian small stress proteins.Large potentials of small heat shock proteins.Contribution of small heat shock proteins to muscle development and function.Targeting Hsp90 and its co-chaperones to treat Alzheimer's disease Ras-GAP binding and phosphorylation by herpes simplex virus type 2 RR1 PK (ICP10) and activation of the Ras/MEK/MAPK mitogenic pathway are required for timely onset of virus growth.The herpes simplex virus type 2 R1 protein kinase (ICP10 PK) functions as a dominant regulator of apoptosis in hippocampal neurons involving activation of the ERK survival pathway and upregulation of the antiapoptotic protein Bag-1.Interaction of mammalian Hsp22 with lipid membranes.Overload of the heat-shock protein H11/HspB8 triggers melanoma cell apoptosis through activation of transforming growth factor-beta-activated kinase 1.H11 has dose-dependent and dual hypertrophic and proapoptotic functions in cardiac myocytes.Mammalian Hsp22 is a heat-inducible small heat-shock protein with chaperone-like activity.Forced expression of the H11 heat shock protein can be regulated by DNA methylation and trigger apoptosis in human cells.The R1 subunit of herpes simplex virus ribonucleotide reductase has chaperone-like activity similar to Hsp27.Neonatal neuronal apoptosis after betamethasone administration in pregnant Wistar rats.Developmental expression patterns of the zebrafish small heat shock proteins.The GABAA Receptor α2 Subunit Activates a Neuronal TLR4 Signal in the Ventral Tegmental Area that Regulates Alcohol and Nicotine Abuse.Heat shock protein 22 overexpression is associated with the progression and prognosis in gastric cancer.

P2860

Q24301950-F401BC56-C85A-4228-B73E-405006328962 Q24563241-0A562545-70CE-4B6C-807D-F3CDA2B46594 Q28187877-6EE846C3-952A-49FA-85F5-9F82ABB94683 Q33924001-3D5F5C85-9A7D-4ECA-B36E-2325203321D2 Q33930977-EC01F734-AE8A-43D2-9099-CF61D7399E4E Q34097680-09C9B220-A592-4B15-88BC-D4D9EF37ADF6 Q34784422-3E364BB6-3DBF-4D19-92B5-60ED816A58EA Q35037004-AA761EC0-ACEB-4E3A-878F-7F8EEB5F64D8 Q36015677-4E022833-8834-45BD-9CD4-20EFCC2D8159 Q36211477-6A872E1A-FC8C-49B4-8D29-6B5DA6626AC2 Q36259341-781A9415-7CB3-4BDF-89D1-8092C0F1AF1E Q36276295-E4A0E0B8-431B-4BCB-AA7C-EFAE6E08ED2E Q36296410-5B1295CD-304B-433F-B6AC-C9DFD4A295FC Q36900533-22A18DDC-5BB2-4E78-9E6F-586599B62DD6 Q36996391-EBD5EC8E-C1D1-45FD-9FC7-21A1E3BD11E0 Q37490527-EFF03FBC-F9B1-4984-B080-7949E95E94C8 Q37947562-AA15F728-4D4D-4E66-AB23-FF94DDBAD1D1 Q38179729-C924517B-DB55-48D1-B2D2-1997A56D5DD9 Q38234720-EAD239F7-3100-49C4-B653-765AEEE61943 Q39585343-E2BCE2B7-C372-4DD3-BB99-404A353A6DF5 Q39699169-7CD97BB7-4C35-4BDA-A9EC-FA605368FABD Q40223755-EE324040-37DE-45BB-B23F-6993E8A0C1E7 Q41854575-6BDC3F27-FA0D-457B-B0A9-2497B45E780B Q42041495-CEE7A29C-510C-49A9-AA92-5472222CDD45 Q42214286-787A7684-601B-4997-A4E5-C3E142C3797F Q44073238-AF5C442D-CACC-4CF4-B376-C1A721DFFBE7 Q44476890-E8E62097-4116-4CEB-800C-4949B4720B2C Q48203354-47728249-B54D-49CD-B62A-8F04524C1DC2 Q51968633-7CDD3B37-41FE-4935-BE8C-CC9D8384709B Q53402920-FCE9FF6F-328F-444A-902B-DDBA9EF01804 Q54354560-FBE71D73-C5F9-426B-AF6C-4EE7F5966433

P2860

A novel human gene similar to the protein kinase (PK) coding domain of the large subunit of herpes simplex virus type 2 ribonucleotide reductase (ICP10) codes for a serine-threonine PK and is expressed in melanoma cells.

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http://www.wikidata.org/entity/Q30655101

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2000 nî lūn-bûn

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2000 թվականի օգոստոսին հրատարակված գիտական հոդված

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2000年の論文

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