A recombinant, fully human monoclonal antibody with antitumor activity constructed from phage-displayed antibody fragments.
about
The epithelial cellular adhesion molecule (Ep-CAM) is a ligand for the leukocyte-associated immunoglobulin-like receptor (LAIR)Nanobodies as novel agents for cancer therapy.Use of real-time polymerase chain reaction to identify cell- and tissue-type-selective peptides by phage display.Nectin-like protein 2 defines a subset of T-cell zone dendritic cells and is a ligand for class-I-restricted T-cell-associated molecule.Isolation of specific and biologically active peptides that bind cells from patients with acute myeloid leukemia (AML).A novel high-affinity human monoclonal antibody to mesothelin.A novel in vivo method for isolating antibodies from a phage display library by neuronal retrograde transport selectively yields antibodies against p75(NTR.).The influence of antibody fragment format on phage display based affinity maturation of IgG.Selection strategies for anticancer antibody discovery: searching off the beaten path.Demystified...recombinant antibodies.Optimizing therapeutic antibody function: progress with Fc domain engineering.A fully human anti-Ep-CAM scFv-beta-glucuronidase fusion protein for selective chemotherapy with a glucuronide prodrug.Efficient and selective gene transfer into primary human brain tumors by using single-chain antibody-targeted adenoviral vectors with native tropism abolished.Exceptionally potent anti-tumor bystander activity of an scFv:sTRAIL fusion protein with specificity for EGP2 toward target antigen-negative tumor cells.In vitro and in vivo pharmacology and pharmacokinetics of a human engineered monoclonal antibody to epithelial cell adhesion moleculeTargeting immune effector molecules to human tumor cells through genetic delivery of 5T4-specific scFv fusion proteins.Secreted and tumour targeted human carboxylesterase for activation of irinotecanLessons learned about the therapeutic potential of the natural human immune response to lung cancer.A Fluorescent Imaging Probe Based on a Macrocyclic Scaffold That Binds to Cellular EpCAM.Selective targeting of tumoral vasculature: Comparison of different formats of an antibody (L19) to the ED-B domain of fibronectin
P2860
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P2860
A recombinant, fully human monoclonal antibody with antitumor activity constructed from phage-displayed antibody fragments.
description
1999 nî lūn-bûn
@nan
1999 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մարտին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
A recombinant, fully human mon ...... -displayed antibody fragments.
@ast
A recombinant, fully human mon ...... -displayed antibody fragments.
@en
type
label
A recombinant, fully human mon ...... -displayed antibody fragments.
@ast
A recombinant, fully human mon ...... -displayed antibody fragments.
@en
prefLabel
A recombinant, fully human mon ...... -displayed antibody fragments.
@ast
A recombinant, fully human mon ...... -displayed antibody fragments.
@en
P2093
P2860
P356
P1433
P1476
A recombinant, fully human mon ...... -displayed antibody fragments.
@en
P2093
A R van der Vuurst de Vries
G P van Berge Henegouwen
I A Heijnen
J C Koningsberger
J de Kruif
M van Meijer
P2860
P2888
P304
P356
10.1038/7023
P577
1999-03-01T00:00:00Z