Trypanosoma brucei RNA triphosphatase. Antiprotozoal drug target and guide to eukaryotic phylogeny.
about
The RNA capping machinery as an anti-infective targetFunctional characterization of a 48 kDa Trypanosoma brucei cap 2 RNA methyltransferaseEvolutionary patterning: a novel approach to the identification of potential drug target sites in Plasmodium falciparumThiamine triphosphatase and the CYTH superfamily of proteins.Polyphosphatase activity of CthTTM, a bacterial triphosphate tunnel metalloenzyme.Novel triphosphate phosphohydrolase activity of Clostridium thermocellum TTM, a member of the triphosphate tunnel metalloenzyme superfamily.Structure-function analysis of Plasmodium RNA triphosphatase and description of a triphosphate tunnel metalloenzyme superfamily that includes Cet1-like RNA triphosphatases and CYTH proteins.Homodimeric quaternary structure is required for the in vivo function and thermal stability of Saccharomyces cerevisiae and Schizosaccharomyces pombe RNA triphosphatases.Development and validation of a high-density fluorescence polarization-based assay for the trypanosoma RNA triphosphatase TbCet1.Trypanosoma brucei translation initiation factor homolog EIF4E6 forms a tripartite cytosolic complex with EIF4G5 and a capping enzyme homolog.Characterization of a Trypanosoma brucei RNA cap (guanine N-7) methyltransferaseThe messenger RNA decapping and recapping pathway in Trypanosoma.A plethora of targets, a paucity of drugs: progress towards the development of novel chemotherapies for human African trypanosomiasis.Nanomolar Inhibitors of Trypanosoma brucei RNA Triphosphatase.Evidence for a capping enzyme with specificity for the trypanosome spliced leader RNA.Chlorella virus RNA triphosphatase. Mutational analysis and mechanism of inhibition by tripolyphosphate.Structure-function analysis of Trypanosoma brucei RNA triphosphatase and evidence for a two-metal mechanism.Yeast-like mRNA capping apparatus in Giardia lamblia.The TbMTr1 spliced leader RNA cap 1 2'-O-ribose methyltransferase from Trypanosoma brucei acts with substrate specificity.What messenger RNA capping tells us about eukaryotic evolution.
P2860
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P2860
Trypanosoma brucei RNA triphosphatase. Antiprotozoal drug target and guide to eukaryotic phylogeny.
description
2001 nî lūn-bûn
@nan
2001 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի սեպտեմբերին հրատարակված գիտական հոդված
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2001年の論文
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2001年学术文章
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2001年学术文章
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2001年学术文章
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2001年学术文章
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2001年学术文章
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2001年學術文章
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name
Trypanosoma brucei RNA triphos ...... guide to eukaryotic phylogeny.
@ast
Trypanosoma brucei RNA triphos ...... guide to eukaryotic phylogeny.
@en
type
label
Trypanosoma brucei RNA triphos ...... guide to eukaryotic phylogeny.
@ast
Trypanosoma brucei RNA triphos ...... guide to eukaryotic phylogeny.
@en
prefLabel
Trypanosoma brucei RNA triphos ...... guide to eukaryotic phylogeny.
@ast
Trypanosoma brucei RNA triphos ...... guide to eukaryotic phylogeny.
@en
P2860
P921
P356
P1476
Trypanosoma brucei RNA triphos ...... guide to eukaryotic phylogeny.
@en
P2860
P304
46182-46186
P356
10.1074/JBC.M108706200
P407
P577
2001-09-11T00:00:00Z