TRB3 links insulin/IGF to tumour promotion by interacting with p62 and impeding autophagic/proteasomal degradations
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P62: An emerging oncotarget for osteolytic metastasisEnergy sensing pathways: Bridging type 2 diabetes and colorectal cancer?A novel ECG analog 4-(S)-(2,4,6-trimethylthiobenzyl)-epigallocatechin gallate selectively induces apoptosis of B16-F10 melanoma via activation of autophagy and ROS.Tamoxifen activates Nrf2-dependent SQSTM1 transcription to promote endometrial hyperplasiaRole of insulin receptor substrates in the progression of hepatocellular carcinoma.A novel crosstalk between CCAR2 and AKT pathway in the regulation of cancer cell proliferationAssessment of Human Tribbles Homolog 3 Genetic Variation (rs2295490) Effects on Type 2 Diabetes Patients with Glucose Control and Blood Pressure Lowering Treatment.Antagonism of Interleukin-17A ameliorates experimental hepatic fibrosis by restoring the IL-10/STAT3-suppressed autophagy in hepatocytes.Sophopterocarpan A, a novel pterocarpine derivative with a benzotetrahydrofuran-fused bicyclo [3.3.1] nonane from Sophora flavescens.Prevention of tumour cell apoptosis associated with sustained protein kinase B phosphorylation is more sensitive to regulation by insulin signalling than stimulation of proliferation and extracellular signal-regulated kinase.p62/SQSTM1-Dr. Jekyll and Mr. Hyde that prevents oxidative stress but promotes liver cancer.Autophagy as a target for development of anti-diabetes drugs derived from natural compounds.Seeking new anti-cancer agents from autophagy-regulating natural products.Competition between members of the tribbles pseudokinase protein family shapes their interactions with mitogen activated protein kinase pathways.Overexpression of the transcription factor ATF3 with a regulatory molecular signature associates with the pathogenic development of colorectal cancer.Targeting TRIB3 and PML-RARα interaction against APL.The real role of pseudokinase: linking diabetes to cancers.TRIB3-P62 interaction, diabetes and autophagy.Cigarette smoke promotes COPD by activating platelet-activating factor receptor and inducing neutrophil autophagic death in mice.The lncRNA HULC functions as an oncogene by targeting ATG7 and ITGB1 in epithelial ovarian carcinoma.Urban fine particulate matter (PM2.5) exposure destroys blood-testis barrier (BTB) integrity through excessive ROS-mediated autophagy.LFM-A13, a potent inhibitor of polo-like kinase, inhibits breast carcinogenesis by suppressing proliferation activity and inducing apoptosis in breast tumors of mice.Targeting pseudokinase TRIB3 brings about a new therapeutic option for acute promyelocytic leukemia.Relation of the IGF/IGF1R system to autophagy in colitis and colorectal cancer.High glucose contributes to the proliferation and migration of non-small cell lung cancer cells via GAS5-TRIB3 axis.Identification of the Functional Autophagy-Regulatory Domain in HCLS1-Associated Protein X-1 That Resists Against Oxidative Stress.Inflammatory-Related P62 Triggers Malignant Transformation of Mesenchymal Stem Cells through the Cascade of CUDR-CTCF-IGFII-RAS Signaling.
P2860
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P2860
TRB3 links insulin/IGF to tumour promotion by interacting with p62 and impeding autophagic/proteasomal degradations
description
2015 nî lūn-bûn
@nan
2015 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
TRB3 links insulin/IGF to tumo ...... hagic/proteasomal degradations
@ast
TRB3 links insulin/IGF to tumo ...... hagic/proteasomal degradations
@en
type
label
TRB3 links insulin/IGF to tumo ...... hagic/proteasomal degradations
@ast
TRB3 links insulin/IGF to tumo ...... hagic/proteasomal degradations
@en
prefLabel
TRB3 links insulin/IGF to tumo ...... hagic/proteasomal degradations
@ast
TRB3 links insulin/IGF to tumo ...... hagic/proteasomal degradations
@en
P2093
P2860
P356
P1476
TRB3 links insulin/IGF to tumo ...... hagic/proteasomal degradations
@en
P2093
Jian-Dong Jiang
Jiao-Jiao Yu
Shuang Shang
P2860
P2888
P356
10.1038/NCOMMS8951
P407
P577
2015-08-13T00:00:00Z
P5875
P6179
1037102168