Identification of a glioblastoma-associated tenascin-C isoform by a high affinity recombinant antibody - Wikidata - awgldk - TriplyDB

Identification of a glioblastoma-associated tenascin-C isoform by a high affinity recombinant antibody

Identification of a glioblastoma-associated tenascin-C isoform by a high affinity recombinant antibody

http://www.wikidata.org/entity/Q30700459

about

Tenascin-C: Form versus function Clinical impact and functional aspects of tenascin-C expression during glioma progression Antibody drug-conjugates targeting the tumor vasculature: Current and future developments Molecular ultrasound assessment of tumor angiogenesis Design, construction, and characterization of a large synthetic human antibody phage display library.Global analysis of aberrant pre-mRNA splicing in glioblastoma using exon expression arrays.Anaplastic oligo-astrocytoma occurring after resection of a cerebral cavernous malformation; malignant transformation? Case report and review on etiology.Association of invasion-promoting tenascin-C additional domains with breast cancers in young women.Molecular imaging in cancer treatment.Failure of anti tumor-derived endothelial cell immunotherapy depends on augmentation of tumor hypoxia.Tenascin-C is expressed by human glioma in vivo and shows a strong association with tumor blood vessels.Tenascins and the importance of adhesion modulation.A highly functional synthetic phage display library containing over 40 billion human antibody clones.The tumor-targeting immunocytokine F16-IL2 in combination with doxorubicin: dose escalation in patients with advanced solid tumors and expansion into patients with metastatic breast cancer.Differentiation between high- and low-grade astrocytoma using a human recombinant antibody to the extra domain-B of fibronectin.Antibody-mediated delivery of IL-10 inhibits the progression of established collagen-induced arthritis Involvement of large tenascin-C splice variants in breast cancer progression Monoclonal antibodies for brain tumour treatment.The role of the extracellular matrix in angiogenesis in malignant glioma tumors.Ligand-based vascular targeting of disease.Glioma-specific antigens for immune tumor therapy.Tumour-associated tenascin-C isoforms promote breast cancer cell invasion and growth by matrix metalloproteinase-dependent and independent mechanisms Preclinical characterization of DEKAVIL (F8-IL10), a novel clinical-stage immunocytokine which inhibits the progression of collagen-induced arthritis.Anticancer strategies involving the vasculature.Expression of tenascin-C and its isoforms in the breast.Jekyll and Hyde: the role of the microenvironment on the progression of cancer.Tumour vasculature targeting agents in hybrid/conjugate drugs.Immunocytokines: a review of molecules in clinical development for cancer therapy.Novel antitenascin antibody with increased tumour localisation for Pretargeted Antibody-Guided RadioImmunoTherapy (PAGRIT).Role of tenascins in the ECM of gliomas.The role of tenascin-C in tissue injury and tumorigenesis.Neural stem/progenitor cells express 20 tenascin C isoforms that are differentially regulated by Pax6.In vivo protein biotinylation for identification of organ-specific antigens accessible from the vasculature.B and C domain containing tenascin-C: urinary markers for invasiveness of urothelial carcinoma of the urinary bladder?Differential expression of tenascin-C splicing domains in urothelial carcinomas of the urinary bladder.Tenascin-C expression relates to clinicopathological features in pilocytic and diffuse astrocytomas.

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P2860

Identification of a glioblastoma-associated tenascin-C isoform by a high affinity recombinant antibody

http://www.wikidata.org/entity/Q30700459

description

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The American Journal of Pathology

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Identification of a glioblasto ...... affinity recombinant antibody

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An alternatively spliced region of the human hexabrachion contains a repeat of potential N-glycosylation sites

Human tenascin: primary structure, pre-mRNA splicing patterns and localization of the epitopes recognized by two monoclonal antibodies

Human tenascin gene. Structure of the 5'-region, identification, and characterization of the transcription regulatory sequences

Tenascin-C, tenascin-R and tenascin-X: a family of talented proteins in search of functions

Angiogenesis in cancer, vascular, rheumatoid and other disease

A single protocol to detect transcripts of various types and expression levels in neural tissue and cultured cells: in situ hybridization using digoxigenin-labelled cRNA probes

Human antibodies with sub-nanomolar affinities isolated from a large non-immunized phage display library.

Cytotactin: a morphoregulatory molecule and a target for regulation by homeobox gene products.

Making antibodies by phage display technology.

A novel tenascin type III repeat is part of a complex of tenascin mRNA alternative splices.

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