High-throughput method for the production and analysis of large natural product libraries for drug discovery. - Wikidata - awgldk - TriplyDB

High-throughput method for the production and analysis of large natural product libraries for drug discovery.

High-throughput method for the production and analysis of large natural product libraries for drug discovery.

http://www.wikidata.org/entity/Q30713866

about

Discovery and resupply of pharmacologically active plant-derived natural products: A review Abronione, a rotenoid from the desert annual Abronia villosa Integration of Microfractionation, qNMR and zebrafish screening for the in vivo bioassay-guided isolation and quantitative bioactivity analysis of natural products Modern natural products drug discovery and its relevance to biodiversity conservation Dereplication of natural products using minimal NMR data inputs.Automated microflow NMR: routine analysis of five-microliter samples Marine natural product libraries for high-throughput screening and rapid drug discovery Fractionated marine invertebrate extract libraries for drug discovery.Pre-fractionated microbial samples--the second generation natural products library at Wyeth.Psammaplin A as a general activator of cell-based signaling assays via HDAC inhibition and studies on some bromotyrosine derivatives Automated high-throughput system to fractionate plant natural products for drug discovery.Natural Products as a Foundation for Drug Discovery.Screening and identification of novel biologically active natural compounds.Differential gene expression for investigation of Escherichia coli biofilm inhibition by plant extract ursolic acid.Discovery of cationic polymers for non-viral gene delivery using combinatorial approaches.From single to multiple microcoil flow probe NMR and related capillary techniques: a review.Natural product libraries to accelerate the high-throughput discovery of therapeutic leads Universal quantification of structurally diverse natural products using an evaporative light scattering detector.Guiding principles for natural product drug discovery.Concepts and technologies for tracking bioactive compounds in natural product extracts: generation of libraries, and hyphenation of analytical processes with bioassays.Are natural products still the best source for antibacterial discovery? The bacterial entry factor.The future of plant drug discovery.Front-loading natural-product-screening libraries for log P: background, development, and implementation.The identification of naturally occurring neoruscogenin as a bioavailable, potent, and high-affinity agonist of the nuclear receptor RORα (NR1F1).A ligand-observed mass spectrometry approach integrated into the fragment based lead discovery pipeline.UPLC-MS-ELSD-PDA as a powerful dereplication tool to facilitate compound identification from small-molecule natural product libraries.New methods to explore marine resources for Alzheimer's therapeutics.NMR spectroscopic search module for Spektraris, an online resource for plant natural product identification--Taxane diterpenoids from Taxus × media cell suspension cultures as a case study Polyoxygenated cyclohexene derivatives from Monanthotaxis congoensis Strategies for facilitated forward chemical genetics.Analysis and purification of bioactive natural products: the AnaPurNa study.A routine experimental protocol for qHNMR illustrated with Taxol.Cytotoxic and antibacterial beilschmiedic acids from a Gabonese species of Beilschmiedia Rapid Bioassay-Guided Isolation of Antibacterial Clerodane Type Diterpenoid from Dodonaea viscosa (L.) Jaeq.Coupling flash liquid chromatography with mass spectrometry for enrichment and isolation of milk oligosaccharides for functional studies.The Amaryllidaceae alkaloids: biosynthesis and methods for enzyme discovery.Determination of binding constants by affinity capillary electrophoresis, electrospray ionization mass spectrometry and phase-distribution methods.Development of a Magnetic Microbead Affinity Selection Screen (MagMASS) Using Mass Spectrometry for Ligands to the Retinoid X Receptor-α.Antiproliferative activity of hamigerone and radicinol isolated from Bipolaris papendorfii.Asiatic acid and corosolic acid enhance the susceptibility of Pseudomonas aeruginosa biofilms to tobramycin.

P2860

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P2860

High-throughput method for the production and analysis of large natural product libraries for drug discovery.

http://www.wikidata.org/entity/Q30713866

description

2002 nî lūn-bûn

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2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2002 թվականի օգոստոսին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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2002年论文

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High-throughput method for the ...... libraries for drug discovery.

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Caroline T Williams

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Chris M Lee

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Gary R Eldridge

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Lu Zeng

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10.1021/AC025534S

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