Eliminating microglia in Alzheimer's mice prevents neuronal loss without modulating amyloid-β pathology. - Wikidata - awgldk - TriplyDB

Eliminating microglia in Alzheimer's mice prevents neuronal loss without modulating amyloid-β pathology.

Eliminating microglia in Alzheimer's mice prevents neuronal loss without modulating amyloid-β pathology.

http://www.wikidata.org/entity/Q30805627

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Regulation of Ketone Body Metabolism and the Role of PPARα Interactions between inflammation, sex steroids, and Alzheimer's disease risk factors Central Nervous System: (Immunological) Ivory Tower or Not?Colony-stimulating factor 1 receptor blockade prevents fractionated whole-brain irradiation-induced memory deficits Neuronal p38α mediates synaptic and cognitive dysfunction in an Alzheimer's mouse model by controlling β-amyloid production.Early microgliosis precedes neuronal loss and behavioural impairment in mice with a frontotemporal dementia-causing CHMP2B mutation Targeting colony stimulating factor 1 receptor to prevent cognitive deficits induced by fractionated whole-brain irradiation.Late onset Alzheimer's disease genetics implicates microglial pathways in disease risk.An updated assessment of microglia depletion: current concepts and future directions.Immunoproteasome deficiency alters microglial cytokine response and improves cognitive deficits in Alzheimer's disease-like APPPS1 mice.The endocytic pathway in microglia during health, aging and Alzheimer's disease.Elimination of microglia improves cognitive function following cranial irradiation Environmental Enrichment Potently Prevents Microglia-Mediated Neuroinflammation by Human Amyloid β-Protein Oligomers Soluble phospho-tau from Alzheimer's disease hippocampus drives microglial degeneration.HuCNS-SC Human NSCs Fail to Differentiate, Form Ectopic Clusters, and Provide No Cognitive Benefits in a Transgenic Model of Alzheimer's Disease.Studies on Colony Stimulating Factor Receptor-1 and Ligands Colony Stimulating Factor-1 and Interleukin-34 in Alzheimer's Disease Brains and Human Microglia EFAD transgenic mice as a human APOE relevant preclinical model of Alzheimer's disease.Microglial Interferon Signaling and White Matter.Developmental toxicant exposure in a mouse model of Alzheimer's disease induces differential sex-associated microglial activation and increased susceptibility to amyloid accumulation.Inflammation in Alzheimer's disease: Lessons learned from microglia-depletion models.Multitasking Microglia and Alzheimer's Disease: Diversity, Tools and Therapeutic Targets.Clearance of cerebral Aβ in Alzheimer's disease: reassessing the role of microglia and monocytes.Effect of Neuroinflammation on Synaptic Organization and Function in the Developing Brain: Implications for Neurodevelopmental and Neurodegenerative Disorders.The human-specific CASP4 gene product contributes to Alzheimer-related synaptic and behavioural deficits.Intracranial IL-17A overexpression decreases cerebral amyloid angiopathy by upregulation of ABCA1 in an animal model of Alzheimer's disease.Lessons Learned about Neurodegeneration from Microglia and Monocyte Depletion Studies.The protective effect of Epimedii Folium and Curculiginis Rhizoma on Alzheimer's disease by the inhibitions of NF-κB/MAPK pathway and NLRP3 inflammasome.HDAC3 negatively regulates spatial memory in a mouse model of Alzheimer's disease.Infection of microglia with Porphyromonas gingivalis promotes cell migration and an inflammatory response through the gingipain-mediated activation of protease-activated receptor-2 in mice.The transcription factor XBP1 in memory and cognition: Implications in Alzheimer disease.Three-way interaction model to trace the mechanisms involved in Alzheimer's disease transgenic mice Microglia-Synapse Pathways: Promising Therapeutic Strategy for Alzheimer's Disease.Microglia limit the expansion of β-amyloid plaques in a mouse model of Alzheimer's disease.The roles of inflammation and immune mechanisms in Alzheimer's disease.Microglial repopulation resolves inflammation and promotes brain recovery after injury.Microglia-Mediated Neuroprotection, TREM2, and Alzheimer's Disease: Evidence From Optical Imaging.The role of microglia and their CX3CR1 signaling in adult neurogenesis in the olfactory bulb.Alzheimer's Disease: The Role of Microglia in Brain Homeostasis and Proteopathy.Kv1.3 inhibition as a potential microglia-targeted therapy for Alzheimer's disease: preclinical proof of concept.Detection of Aβ plaque-associated astrogliosis in Alzheimer's disease brain by spectroscopic imaging and immunohistochemistry.

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Eliminating microglia in Alzheimer's mice prevents neuronal loss without modulating amyloid-β pathology.

http://www.wikidata.org/entity/Q30805627

description

2016 nî lūn-bûn

@nan

2016 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2016 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2016年の論文

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2016年論文

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2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

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2016年論文

@zh-tw

2016年论文

@wuu

name

Eliminating microglia in Alzhe ...... odulating amyloid-β pathology.

@ast

Eliminating microglia in Alzhe ...... odulating amyloid-β pathology.

@en

type

label

Eliminating microglia in Alzhe ...... odulating amyloid-β pathology.

@ast

Eliminating microglia in Alzhe ...... odulating amyloid-β pathology.

@en

prefLabel

Eliminating microglia in Alzhe ...... odulating amyloid-β pathology.

@ast

Eliminating microglia in Alzhe ...... odulating amyloid-β pathology.

@en

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Eliminating microglia in Alzhe ...... modulating amyloid-β pathology

@en

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Allison R Najafi

http://www.w3.org/2001/XMLSchema#string

Elizabeth E Spangenberg

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Kim N Green

http://www.w3.org/2001/XMLSchema#string

Monica R P Elmore

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Rachel A Rice

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Rafael J Lee

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P2860

Persistent amyloidosis following suppression of Abeta production in a transgenic model of Alzheimer disease

TREM2 Variants in Alzheimer's Disease

Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology

Clathrin adaptor CALM/PICALM is associated with neurofibrillary tangles and is cleaved in Alzheimer's brains

Depletion of microglia and inhibition of exosome synthesis halt tau propagation.

Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor

Identification of a unique TGF-β-dependent molecular and functional signature in microglia

Arginine deprivation and immune suppression in a mouse model of Alzheimer's disease

Beta-amyloid stimulation of inducible nitric-oxide synthase in astrocytes is interleukin-1beta- and tumor necrosis factor-alpha (TNFalpha)-dependent, and involves a TNFalpha receptor-associated factor- and NFkappaB-inducing kinase-dependent signalin

Deletion of Abca7 increases cerebral amyloid-β accumulation in the J20 mouse model of Alzheimer's disease

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1265-1281

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scholarly article

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10.1093/BRAIN/AWW016

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Pt 4

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139

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Mathew Blurton-Jones

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2016-02-26T00:00:00Z

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296193863

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26921617

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Alzheimer's disease

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5006229

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