Establishment of a gene-trap sequence tag library to generate mutant mice from embryonic stem cells. - Wikidata - awgldk - TriplyDB

Establishment of a gene-trap sequence tag library to generate mutant mice from embryonic stem cells.

Establishment of a gene-trap sequence tag library to generate mutant mice from embryonic stem cells.

http://www.wikidata.org/entity/Q30829772

about

The knockout mouse project The European dimension for the mouse genome mutagenesis program Disruption of the gene encoding the latent transforming growth factor-beta binding protein 4 (LTBP-4) causes abnormal lung development, cardiomyopathy, and colorectal cancer Gene trap mutagenesis of hnRNP A2/B1: a cryptic 3' splice site in the neomycin resistance gene allows continued expression of the disrupted cellular gene Discovery of mammalian genes that participate in virus infection Gene trap and gene inversion methods for conditional gene inactivation in the mouse Gene trapping identifies transiently induced survival genes during programmed cell death The trappist's approach to pathfinding: elucidating brain wiring using secretory-trap mutagenesis The International Gene Trap Consortium Website: a portal to all publicly available gene trap cell lines in mouse High-throughput trapping of secretory pathway genes in mouse embryonic stem cells.Mouse models for human otitis media Creation of genome-wide protein expression libraries using random activation of gene expression Sall1, sall2, and sall4 are required for neural tube closure in mice Transcriptional regulator BPTF/FAC1 is essential for trophoblast differentiation during early mouse development Knockout of the regulatory factor X1 gene leads to early embryonic lethality.The Mammalian Phenotype Ontology as a unifying standard for experimental and high-throughput phenotyping data Genetic screens in mammalian cells by enhanced retroviral mutagens.Gene trap: a way to identify novel genes and unravel their biological function.Screening insertion libraries for mutations in many genes simultaneously using DNA microarrays.Post-entrapment genome engineering: first exon size does not affect the expression of fusion transcripts generated by gene entrapment Genome-wide insertional mutagenesis in human cells by the Drosophila mobile element Minos.Genomewide trapping of genes that encode secreted and transmembrane proteins repressed by oncogenic signaling.Genomewide production of multipurpose alleles for the functional analysis of the mouse genome.Comparison of methods for genomic localization of gene trap sequences Proteomic shifts in embryonic stem cells with gene dose modifications suggest the presence of balancer proteins in protein regulatory networks.Pleiotropic effects in Eya3 knockout mice.Generation of mouse mutants as a tool for functional genomics.Production of transgenic rats by lentiviral transduction of male germ-line stem cells mTrop1/Epcam knockout mice develop congenital tufting enteropathy through dysregulation of intestinal E-cadherin/β-catenin.The mouse: genetics meets behaviour.Of mice and models: improved animal models for biomedical research.Evolutionarily conserved role of nucleostemin: controlling proliferation of stem/progenitor cells during early vertebrate development.A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.The Arp2/3 complex is required for lamellipodia extension and directional fibroblast cell migration.Mouse models as a tool to unravel the genetic basis for human otitis media.Gene trap mutagenesis: a functional genomics approach towards reproductive research.Expression profiling with arrays of randomly disrupted genes in mouse embryonic stem cells leads to in vivo functional analysis Beyond knockouts: the International Knockout Mouse Consortium delivers modular and evolving tools for investigating mammalian genes.Activation of cryptic 3' splice sites within introns of cellular genes following gene entrapment The UniTrap resource: tools for the biologist enabling optimized use of gene trap clones.

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P2860

Establishment of a gene-trap sequence tag library to generate mutant mice from embryonic stem cells.

http://www.wikidata.org/entity/Q30829772

description

2000 nî lūn-bûn

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2000 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2000 թվականի հունվարին հրատարակված գիտական հոդված

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2000年の論文

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2000年論文

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2000年論文

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2000年論文

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2000年論文

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Nature Genetics

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Establishment of a gene-trap s ...... ice from embryonic stem cells.

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P2093

Arnold HH

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Füchtbauer A

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Füchtbauer EM

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Lehrach H

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Wiles MV

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Wurst W

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P2860

Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice

Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells.

A gene trap approach in mouse embryonic stem cells: the lacZ reported is activated by splicing, reflects endogenous gene expression, and is mutagenic in mice.

Functional genomics in mice by tagged sequence mutagenesis.

Fluorescence-activated sorting of totipotent embryonic stem cells expressing developmentally regulated lacZ fusion genes

Evidence for the stochastic integration of gene trap vectors into the mouse germline.

An efficient gene-trap method using poly A trap vectors and characterization of gene-trap events.

Selective disruption of genes expressed in totipotent embryonal stem cells.

A new strategy of gene trapping in ES cells using 3'RACE.

Efficient poly A trap approach allows the capture of genes specifically active in differentiated embryonic stem cells and in mouse embryos.

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10.1038/71622

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1

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