Computer-assisted mutagenesis of ecotin to engineer its secondary binding site for urokinase inhibition.
about
A urokinase-type plasminogen activator-inhibiting cyclic peptide with an unusual P2 residue and an extended protease binding surface demonstrates new modalities for enzyme inhibition.A new generation of protein display scaffolds for molecular recognition.Prokaryote-derived protein inhibitors of peptidases: A sketchy occurrence and mostly unknown functionThe contribution of key hydrophobic residues in ecotin to enzyme-inhibitor complex stability.Tailoring the specificity of a plant cystatin toward herbivorous insect digestive cysteine proteases by single mutations at positively selected amino acid sites.Structural model of haptoglobin and its complex with the anticoagulant ecotin variants: structure-activity relationship study and analysis of interactions.
P2860
Computer-assisted mutagenesis of ecotin to engineer its secondary binding site for urokinase inhibition.
description
2002 nî lūn-bûn
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2002 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Computer-assisted mutagenesis ...... site for urokinase inhibition.
@ast
Computer-assisted mutagenesis ...... site for urokinase inhibition.
@en
type
label
Computer-assisted mutagenesis ...... site for urokinase inhibition.
@ast
Computer-assisted mutagenesis ...... site for urokinase inhibition.
@en
prefLabel
Computer-assisted mutagenesis ...... site for urokinase inhibition.
@ast
Computer-assisted mutagenesis ...... site for urokinase inhibition.
@en
P2093
P2860
P356
P1476
Computer-assisted mutagenesis ...... site for urokinase inhibition.
@en
P2093
Charles S Craik
Irwin Kuntz
Malin M Young
Martha C A Laboissière
Rilva G Pinho
Robert J Fletterick
Stephen Todd
P2860
P304
26623-26631
P356
10.1074/JBC.M203076200
P407
P577
2002-04-16T00:00:00Z