Mutations in NONO lead to syndromic intellectual disability and inhibitory synaptic defects
about
A crystallographic study of human NONO (p54(nrb)): overcoming pathological problems with purification, data collection and noncrystallographic symmetryProtocadherin 19 (PCDH19) interacts with paraspeckle protein NONO to co-regulate gene expression with estrogen receptor alpha (ERα).AMPA-receptor specific biogenesis complexes control synaptic transmission and intellectual ability.The DBHS proteins SFPQ, NONO and PSPC1: a multipurpose molecular scaffoldDepletion of NEAT1 lncRNA attenuates nucleolar stress by releasing sequestered P54nrb and PSF to facilitate c-Myc translation.BCL11A Haploinsufficiency Causes an Intellectual Disability Syndrome and Dysregulates Transcription.SFPQ•NONO and XLF function separately and together to promote DNA double-strand break repair via canonical nonhomologous end joining.Intellectual disability and non-compaction cardiomyopathy with a de novo NONO mutation identified by exome sequencing.GABA type a receptor trafficking and the architecture of synaptic inhibition.Congenital heart defects and left ventricular non-compaction in males with loss-of-function variants in NONO.Acute hepatotoxicity of 2' fluoro-modified 5-10-5 gapmer phosphorothioate oligonucleotides in mice correlates with intracellular protein binding and the loss of DBHS proteins.Cell-type specific role of the RNA-binding protein, NONO, in the DNA double-strand break response in the mouse testes.Integrative bioinformatics analysis characterizing the role of EDC3 in mRNA decay and its association to intellectual disability.Overexpression of p54nrb/NONO induces differential EPHA6 splicing and contributes to castration-resistant prostate cancer growth.[Mutations in NONO lead to syndromic intellectual disability and inhibitory synaptic defects].Crystal structure of a SFPQ/PSPC1 heterodimer provides insights into preferential heterodimerization of human DBHS family proteins.Common Ribs of Inhibitory Synaptic Dysfunction in the Umbrella of Neurodevelopmental Disorders.
P2860
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P2860
Mutations in NONO lead to syndromic intellectual disability and inhibitory synaptic defects
description
2015 nî lūn-bûn
@nan
2015 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2015年の論文
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2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Mutations in NONO lead to synd ...... nd inhibitory synaptic defects
@ast
Mutations in NONO lead to synd ...... nd inhibitory synaptic defects
@en
type
label
Mutations in NONO lead to synd ...... nd inhibitory synaptic defects
@ast
Mutations in NONO lead to synd ...... nd inhibitory synaptic defects
@en
prefLabel
Mutations in NONO lead to synd ...... nd inhibitory synaptic defects
@ast
Mutations in NONO lead to synd ...... nd inhibitory synaptic defects
@en
P2093
P2860
P50
P356
P1433
P1476
Mutations in NONO lead to synd ...... nd inhibitory synaptic defects
@en
P2093
Aileen Schröter
Ann-Kristina Fritz
Christina Koester
David P Wolfer
Dennis Mircsof
Florence Crestani
Giovanna Bosshard
Katrina Prescott
Ludmila Gaspar
P2860
P2888
P304
P356
10.1038/NN.4169
P407
P50
P577
2015-11-16T00:00:00Z