Evidence for shared recognition of a peptide ligand by a diverse panel of non-obese diabetic mice-derived, islet-specific, diabetogenic T cell clones.

Evidence for shared recognition of a peptide ligand by a diverse panel of non-obese diabetic mice-derived, islet-specific, diabetogenic T cell clones.

Item
http://www.wikidata.org/entity/Q30872028
Chromogranin A is an autoantigen in type 1 diabetesThe diabetogenic mouse MHC class II molecule I-Ag7 is endowed with a switch that modulates TCR affinityReactive oxygen species are required for driving efficient and sustained aerobic glycolysis during CD4+ T cell activation.Analysis of T cell receptor beta chains that combine with dominant conserved TRAV5D-4*04 anti-insulin B:9-23 alpha chainsUse of autoantigen-loaded phosphatidylserine-liposomes to arrest autoimmunity in type 1 diabetesSusceptible MHC alleles, not background genes, select an autoimmune T cell reactivity.Modulation of redox balance leaves murine diabetogenic TH1 T cells "LAG-3-ing" behind.Do MHCII-presented neoantigens drive type 1 diabetes and other autoimmune diseases?N-terminal additions to the WE14 peptide of chromogranin A create strong autoantigen agonists in type 1 diabetesDiabetogenic T-cell clones recognize an altered peptide of chromogranin A.Vaccination with single chain antigen receptors for islet-derived peptides presented on I-A(g7) delays diabetes in NOD mice by inducing anergy in self-reactiveT-cells.Cutting edge: CD4 T cells reactive to an islet amyloid polypeptide peptide accumulate in the pancreas and contribute to disease pathogenesis in nonobese diabetic mice.Cholera toxin subunit B peptide fusion proteins reveal impaired oral tolerance induction in diabetes-prone but not in diabetes-resistant mice.Destabilization of peptide:MHC interaction induces IL-2 resistant anergy in diabetogenic T cells
P2860

Evidence for shared recognition of a peptide ligand by a diverse panel of non-obese diabetic mice-derived, islet-specific, diabetogenic T cell clones.

Item
http://www.wikidata.org/entity/Q30872028
description
2002 nî lūn-bûn
@nan
2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Evidence for shared recognitio ...... c, diabetogenic T cell clones.
@ast
Evidence for shared recognitio ...... c, diabetogenic T cell clones.
@en
type
label
Evidence for shared recognitio ...... c, diabetogenic T cell clones.
@ast
Evidence for shared recognitio ...... c, diabetogenic T cell clones.
@en
prefLabel
Evidence for shared recognitio ...... c, diabetogenic T cell clones.
@ast
Evidence for shared recognitio ...... c, diabetogenic T cell clones.
@en
P1433
P1476
P2093
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921
P356
P1433
P1476
Evidence for shared recognitio ...... c, diabetogenic T cell clones.
@en
P2093
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P921