Recombinant environmental libraries provide access to microbial diversity for drug discovery from natural products. - Wikidata - awgldk - TriplyDB

Recombinant environmental libraries provide access to microbial diversity for drug discovery from natural products.

Recombinant environmental libraries provide access to microbial diversity for drug discovery from natural products.

http://www.wikidata.org/entity/Q30878449

about

Bioinformatics for whole-genome shotgun sequencing of microbial communities Recent application of metagenomic approaches toward the discovery of antimicrobials and other bioactive small molecules Screening for novel enzymes from metagenome and SIGEX, as a way to improve it Targeted metagenomics as a tool to tap into marine natural product diversity for the discovery and production of drug candidates Acylation of Biomolecules in Prokaryotes: a Widespread Strategy for the Control of Biological Function and Metabolic Stress Strategies for discovery and improvement of enzyme function: state of the art and opportunities Metagenomics: Future of microbial gene mining A biological treasure metagenome: pave a way for big science Finding the needles in the metagenome haystack Metagenomics: application of genomics to uncultured microorganisms Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach Metagenomic approaches to understanding phylogenetic diversity in quorum sensing Environmental DNA fragment conferring early and increased sporulation and antibiotic production in Streptomyces species.Estimating P-coverage of biosynthetic pathways in DNA libraries and screening by genetic selection: biotin biosynthesis in the marine microorganism Chromohalobacter.Metagenome survey of biofilms in drinking-water networks.Construction, characterization, and use of small-insert gene banks of DNA isolated from soil and enrichment cultures for the recovery of novel amidases.Uncultured soil bacteria are a reservoir of new antibiotic resistance genes.The metagenomics of soil.Metagenomics and industrial applications.Metagenomic analysis reveals diverse polyketide synthase gene clusters in microorganisms associated with the marine sponge Discodermia dissoluta.Intracellular screen to identify metagenomic clones that induce or inhibit a quorum-sensing biosensor.Characterization of a forest soil metagenome clone that confers indirubin and indigo production on Escherichia coli Comparative genomics of DNA fragments from six Antarctic marine planktonic bacteria.Screening and purification for novel cytochrome b5 from uncultured environmental micro-organisms.Soil eukaryotic functional diversity, a metatranscriptomic approach.The SIGEX scheme: high throughput screening of environmental metagenomes for the isolation of novel catabolic genes.Recovery, purification, and cloning of high-molecular-weight DNA from soil microorganisms.Natural products from environmental DNA hosted in Ralstonia metallidurans Toward cloning of the magnetotactic metagenome: identification of magnetosome island gene clusters in uncultivated magnetotactic bacteria from different aquatic sediments Isolation, diversity, and antimicrobial activity of rare actinobacteria from medicinal plants of tropical rain forests in Xishuangbanna, China.Functional metagenomics to mine the human gut microbiome for dietary fiber catabolic enzymes.Functional characterization of a new holin-like antibacterial protein coding gene tmp1 from goat skin surface metagenome.Size Does Matter: Application-driven Approaches for Soil Metagenomics.Construction and functional screening of a metagenomic library using a T7 RNA polymerase-based expression cosmid vector.Accessing the soil metagenome for studies of microbial diversity.Characterization of novel antibiotic resistance genes identified by functional metagenomics on soil samples.Polyketide synthase pathways identified from a metagenomic library are derived from soil Acidobacteria.Soil-specific limitations for access and analysis of soil microbial communities by metagenomics.The combination of functional metagenomics and an oil-fed enrichment strategy revealed the phylogenetic diversity of lipolytic bacteria overlooked by the cultivation-based method.Human distal gut microbiome.

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Recombinant environmental libraries provide access to microbial diversity for drug discovery from natural products.

http://www.wikidata.org/entity/Q30878449

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AEM.69.1.49-55.2003

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Applied and Environmental Microbiology

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Recombinant environmental libr ...... scovery from natural products.

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Asuncion Martinez

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Carmela M Cappellano

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Francois-Xavier Francou

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Gérard Helynck

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Jean-Luc Pernodet

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Joern Hopke

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Marcia S Osburne

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Michel Guérineau

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Pascal Simonet

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P2860

Novel division level bacterial diversity in a Yellowstone hot spring

Phylogenetic identification and in situ detection of individual microbial cells without cultivation

Basic local alignment search tool

Base-calling of automated sequencer traces using phred. II. Error probabilities

Base-calling of automated sequencer traces using phred. I. Accuracy assessment

Consed: a graphical tool for sequence finishing

A molecular view of microbial diversity and the biosphere

Expression and isolation of antimicrobial small molecules from soil DNA libraries.

Novel natural products from soil DNA libraries in a streptomycete host.

Recombinant approaches for accessing biodiversity.

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49-55

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scholarly article

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10.1128/AEM.69.1.49-55.2003

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1

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Sophie Courtois

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12513976

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