Abrogation of postentry restriction of HIV-1-based lentiviral vector transduction in simian cells.
about
TRIM5α and Species Tropism of HIV/SIVEnhanced at puberty 1 (EAP1) is a new transcriptional regulator of the female neuroendocrine reproductive axisCyclophilin A is required for TRIM5{alpha}-mediated resistance to HIV-1 in Old World monkey cellsSpecific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factorFunctional replacement of the RING, B-box 2, and coiled-coil domains of tripartite motif 5alpha (TRIM5alpha) by heterologous TRIM domainsRetrovirus resistance factors Ref1 and Lv1 are species-specific variants of TRIM5alphaInhibition of human immunodeficiency virus type 1 replication in human cells by Debio-025, a novel cyclophilin binding agentHIV-1 capsid: the multifaceted key player in HIV-1 infectionHematopoietic stem cell gene therapy:assessing the relevance of preclinical modelsNonhuman primate models for HIV/AIDS vaccine developmentNovel Escape Mutants Suggest an Extensive TRIM5α Binding Site Spanning the Entire Outer Surface of the Murine Leukemia Virus Capsid ProteinPolymorphisms in the regulatory region of the Cyclophilin A gene influence the susceptibility for HIV-1 infectionGene expression analysis of a panel of cell lines that differentially restrict HIV-1 CA mutants infection in a cyclophilin a-dependent mannerAccelerated lymphocyte reconstitution and long-term recovery after transplantation of lentiviral-transduced rhesus CD34+ cells mobilized by G-CSF and plerixaforSIV replication in human cellsA specific region of 37 amino acid residues in the SPRY (B30.2) domain of African green monkey TRIM5alpha determines species-specific restriction of simian immunodeficiency virus SIVmac infection.Identification of synthetic endothelial cell-specific promoters by use of a high-throughput screen.The effect of Trim5 polymorphisms on the clinical course of HIV-1 infection.Proteasomal degradation of TRIM5alpha during retrovirus restrictionInducible APOBEC3G-Vif double stable cell line as a high-throughput screening platform to identify antiviral compounds.Transient in vivo beta-globin production after lentiviral gene transfer to hematopoietic stem cells in the nonhuman primateRetrovirus restriction by TRIM5alpha variants from Old World and New World primatesThe B30.2(SPRY) domain of the retroviral restriction factor TRIM5alpha exhibits lineage-specific length and sequence variation in primatesSpecies-specific variation in the B30.2(SPRY) domain of TRIM5alpha determines the potency of human immunodeficiency virus restrictionRecognition of the HIV capsid by the TRIM5α restriction factor is mediated by a subset of pre-existing conformations of the TRIM5α SPRY domain.Retroviral restriction factor TRIM5alpha is a trimerMultiple sites in the N-terminal half of simian immunodeficiency virus capsid protein contribute to evasion from rhesus monkey TRIM5α-mediated restriction.Adaptation of HIV-1 to cells expressing rhesus monkey TRIM5αMicrobial peptidyl-prolyl cis/trans isomerases (PPIases): virulence factors and potential alternative drug targets.Phosphodiesterase 8a supports HIV-1 replication in macrophages at the level of reverse transcriptionGenetic Dissection of the Host Tropism of Human-Tropic Pathogens.Insights into cellular factors that regulate HIV-1 replication in human cellsEvolution of a cytoplasmic tripartite motif (TRIM) protein in cows that restricts retroviral infection.Removal of arginine 332 allows human TRIM5alpha to bind human immunodeficiency virus capsids and to restrict infection.Cyclosporine increases human immunodeficiency virus type 1 vector transduction of primary mouse cells.A cyclophilin homology domain-independent role for Nup358 in HIV-1 infection.Role of TRIM5α RING domain E3 ubiquitin ligase activity in capsid disassembly, reverse transcription blockade, and restriction of simian immunodeficiency virus.Cyclophilin A, TRIM5, and resistance to human immunodeficiency virus type 1 infectionHost cell species-specific effect of cyclosporine A on simian immunodeficiency virus replication.Vif counteracts a cyclophilin A-imposed inhibition of simian immunodeficiency viruses in human cells.
P2860
Q24304062-4DFC13F7-99CD-4A3E-9815-767D34A11DE4Q24319029-CF7EF46D-8D6C-48B5-9E90-8C9A74072AACQ24536359-E58D1096-D340-4BA5-B2BE-7D9E1E4A6821Q24547409-9287DA0A-96DB-45A7-84E2-43ED00D24A7CQ24548932-7C937F42-67EB-4E50-9781-3ADF1221555CQ24561939-3ACE4963-B600-4182-8DE4-4DDA801C8283Q24656023-377FAB95-2AF1-478D-9DFE-5640F758BF85Q26801145-4D71E039-FCEA-4C62-A305-B378032D76A2Q26859147-F1C4567D-FDD6-4EAE-AA4C-B6B6EB29B190Q26861148-6F4F71C3-D39E-494A-B0D7-A21F1533708CQ27667494-FB081D5C-E2B9-4CA0-8569-972BD46AB05AQ28474342-500DC6A4-E81A-4E15-950A-EACE977C6216Q28541423-807A5756-20B3-4839-B9E7-9392724EC28CQ28742157-8FD8CA91-A9F5-480B-A68E-0F6C7817D6BAQ30417737-8E01BECC-F4BD-495B-8CF0-6A7799913CE4Q30789664-C4147D4D-E93E-4B93-BD39-BC9C2228D84CQ31066742-EAF65D3B-3C13-471E-8F35-FDDD0993E3D4Q33318083-9089C073-D8A5-4732-B5DD-EE60E7F06C92Q33337129-24CAA3F2-9D90-42BC-86FF-22671C8252C1Q33511412-ABBBBDD8-B0D0-4B7F-B63F-4C945777A514Q33688435-5E233BA4-F2F1-4C99-9331-68AF59EEBEC0Q33707501-D713B36D-82B3-453B-AD42-86F8129E688AQ33780572-4BA8D304-E009-457D-98B2-39C1491459A0Q33834617-3D7C0AD5-94BF-4246-8270-D3B71718EAEFQ33989616-CD44DD6B-A658-4A70-B8F0-DD3BD94C8A72Q34123929-710E7982-3F4A-470F-8759-4175EC12B421Q34149568-9B9D0490-6D81-4EF4-AED9-74502C58D15AQ34288181-056B8B7E-6CD4-49F7-A12F-E25D3D594EF9Q34297821-7DAFCD5B-5D62-4CF4-97C7-93B29F27E5EAQ34309051-BB49873F-0FDA-4E2E-AF11-2202AA0AFDC8Q34495762-1EF9D996-BD02-4AAE-B86B-7B067B03C5ACQ34561070-F2149722-FCDF-472D-8864-1C62BCD85C87Q34624596-ECF60564-B54F-4368-9A45-25B5A34BC2A9Q34717834-5E816170-B81E-47A2-84CF-1C5D1E69958CQ35023710-4870CFBD-544A-47B5-98E7-5758C4D9557EQ35105663-6267653B-5E8A-47DB-AD32-AFD619A36204Q35140364-087C5FC5-AFB7-47E8-A42A-0BD1C26FEA02Q35635089-0F14971A-C964-49D1-8F09-E6D8B926573BQ35850448-35A5D55A-87A5-4F9F-A04E-7CA196506C52Q35947645-911423AF-E328-43C3-9700-0974D52BD142
P2860
Abrogation of postentry restriction of HIV-1-based lentiviral vector transduction in simian cells.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Abrogation of postentry restri ...... transduction in simian cells.
@ast
Abrogation of postentry restri ...... transduction in simian cells.
@en
type
label
Abrogation of postentry restri ...... transduction in simian cells.
@ast
Abrogation of postentry restri ...... transduction in simian cells.
@en
prefLabel
Abrogation of postentry restri ...... transduction in simian cells.
@ast
Abrogation of postentry restri ...... transduction in simian cells.
@en
P2093
P2860
P356
P1476
Abrogation of postentry restri ...... transduction in simian cells.
@en
P2093
Carsten Munk
Inder M Verma
Nathaniel R Landau
Neeltje A Kootstra
Nina Tonnu
P2860
P304
P356
10.1073/PNAS.0337541100
P407
P577
2003-01-23T00:00:00Z