Glycosylation of human recombinant gonadotrophins: characterization and batch-to-batch consistency.
about
Optimization of the medium perfusion rate in a packed-bed bioreactor charged with CHO cellsBoth core and terminal glycosylation alter epitope expression in thyrotropin and introduce discordances in hormone measurements.Gonadotropin therapy in assisted reproduction: an evolutionary perspective from biologics to biotech.High-level expression of biologically active glycoprotein hormones in Pichia pastoris strains--selection of strain GS115, and not X-33, for the production of biologically active N-glycosylated 15N-labeled phCG.Absence of TGF-β Receptor Activation by Highly Purified hCG Preparations.LH and hCG action on the same receptor results in quantitatively and qualitatively different intracellular signalling.Production, purification, and characterization of recombinant hFSH glycoforms for functional studies.Synthesis and secretion of gonadotropins including structure-function correlates.The classification, functions and clinical use of different isoforms of HCG.Gonadotropins in doping: pharmacological basis and detection of illicit use.Building biologics by chemical synthesis: practical preparation of di- and triantennary N-linked glycoconjugates.Effectiveness of a recombinant human follicle stimulating hormone on the ovarian follicles, peripheral progesterone, estradiol-17β, and pregnancy rate of dairy cows.Analytical challenges in the detection of peptide hormones for anti-doping purposes.Quantification of biopharmaceuticals and biomarkers in complex biological matrices: a comparison of liquid chromatography coupled to tandem mass spectrometry and ligand binding assays.A new fully human recombinant FSH (follitropin epsilon): two phase I randomized placebo and comparator-controlled pharmacokinetic and pharmacodynamic trials.Evaluation of in vivo bioactivities of recombinant hypo- (FSH21/18) and fully- (FSH24) glycosylated human FSH glycoforms in Fshb null mice.LC-MS analysis combined with principal component analysis and soft independent modelling by class analogy for a better detection of changes in N-glycosylation profiles of therapeutic glycoproteins.Probing the frontiers of glycoprotein synthesis: the fully elaborated β-subunit of the human follicle-stimulating hormone.In-vivo biological activity and glycosylation analysis of a biosimilar recombinant human follicle-stimulating hormone product (Bemfola) compared with its reference medicinal product (GONAL-f).Biosimilar FSH preparations- are they identical twins or just siblings?Heterogeneous hCG and hMG commercial preparations result in different intracellular signalling but induce a similar long-term progesterone response in vitro.Evaluation of the oligosaccharide composition of commercial follicle stimulating hormone preparations.In Vivo and In Vitro Impact of Carbohydrate Variation on Human Follicle-Stimulating Hormone Function.
P2860
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P2860
Glycosylation of human recombinant gonadotrophins: characterization and batch-to-batch consistency.
description
2002 nî lūn-bûn
@nan
2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Glycosylation of human recombi ...... nd batch-to-batch consistency.
@ast
Glycosylation of human recombi ...... nd batch-to-batch consistency.
@en
type
label
Glycosylation of human recombi ...... nd batch-to-batch consistency.
@ast
Glycosylation of human recombi ...... nd batch-to-batch consistency.
@en
prefLabel
Glycosylation of human recombi ...... nd batch-to-batch consistency.
@ast
Glycosylation of human recombi ...... nd batch-to-batch consistency.
@en
P2093
P356
P1433
P1476
Glycosylation of human recombi ...... and batch-to-batch consistency
@en
P2093
Alain Van Dorsselaer
Annick Gervais
Emmanuelle Leize
Gianni Baer
Nathalie Carte
Odile Sorokine
Pierre Lepage
Roman Koerner
Sophie Pelloux
Yves-Alexis Hammel
P304
P356
10.1093/GLYCOB/CWG020
P577
2002-11-26T00:00:00Z