Investigation of trypanothione reductase as a drug target in Trypanosoma brucei.
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Dihydroquinazolines as a Novel Class of Trypanosoma brucei Trypanothione Reductase Inhibitors: Discovery, Synthesis, and Characterization of their Binding Mode by Protein CrystallographyGenetic validation of Trypanosoma brucei glutathione synthetase as an essential enzyme.Design, synthesis and biological evaluation of Trypanosoma brucei trypanothione synthetase inhibitors.Design, synthesis and biological evaluation of novel inhibitors of Trypanosoma brucei pteridine reductase 1.Quinol derivatives as potential trypanocidal agentsOxidative Reactivities of 2-Furylquinolines: Ubiquitous Scaffolds in Common High-Throughput Screening Libraries.Inhibition of Leishmania infantum trypanothione reductase by diaryl sulfide derivatives.Development of novel drugs for human African trypanosomiasis.Neglected disease - african sleeping sickness: recent synthetic and modeling advances.Structural insights into the enzymes of the trypanothione pathway: targets for antileishmaniasis drugs.Screening the Medicines for Malaria Venture Pathogen Box across Multiple Pathogens Reclassifies Starting Points for Open-Source Drug Discovery.The Architecture of Thiol Antioxidant Systems among Invertebrate Parasites.Inhibitors of Trypanosoma brucei trypanothione reductase: comparative molecular field analysis modeling and structural basis for selective inhibition.Ebsulfur is a benzisothiazolone cytocidal inhibitor targeting the trypanothione reductase of Trypanosoma brucei.Probing the dimerization interface of Leishmania infantum trypanothione reductase with site-directed mutagenesis and short peptides.
P2860
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P2860
Investigation of trypanothione reductase as a drug target in Trypanosoma brucei.
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Investigation of trypanothione reductase as a drug target in Trypanosoma brucei.
@ast
Investigation of trypanothione reductase as a drug target in Trypanosoma brucei.
@en
type
label
Investigation of trypanothione reductase as a drug target in Trypanosoma brucei.
@ast
Investigation of trypanothione reductase as a drug target in Trypanosoma brucei.
@en
prefLabel
Investigation of trypanothione reductase as a drug target in Trypanosoma brucei.
@ast
Investigation of trypanothione reductase as a drug target in Trypanosoma brucei.
@en
P2093
P2860
P50
P356
P1433
P1476
Investigation of trypanothione reductase as a drug target in Trypanosoma brucei.
@en
P2093
Daniel James
Daniel Spinks
Deuan Jones
Julie A Frearson
Laura A T Cleghorn
Stuart McElroy
P2860
P304
P356
10.1002/CMDC.200900262
P577
2009-12-01T00:00:00Z