The XPA-binding domain of ERCC1 is required for nucleotide excision repair but not other DNA repair pathways. - Wikidata - awgldk - TriplyDB

The XPA-binding domain of ERCC1 is required for nucleotide excision repair but not other DNA repair pathways.

The XPA-binding domain of ERCC1 is required for nucleotide excision repair but not other DNA repair pathways.

http://www.wikidata.org/entity/Q30919478

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Deficient expression of DNA repair enzymes in early progression to sporadic colon cancer Role of the XPA protein in the NER pathway: A perspective on the function of structural disorder in macromolecular assembly Nucleotide excision repair in eukaryotes Mechanism and regulation of incisions during DNA interstrand cross-link repair DNA repair endonuclease ERCC1-XPF as a novel therapeutic target to overcome chemoresistance in cancer therapy Transcriptional and Posttranslational Regulation of Nucleotide Excision Repair: The Guardian of the Genome against Ultraviolet Radiation USP45 deubiquitylase controls ERCC1-XPF endonuclease-mediated DNA damage responses Advances in understanding the complex mechanisms of DNA interstrand cross-link repair Quantification of excision repair cross-complementing group 1 and survival in p16-negative squamous cell head and neck cancers Localization of xeroderma pigmentosum group A protein and replication protein A on damaged DNA in nucleotide excision repair.Strand-specific PCR of UV radiation-damaged genomic DNA revealed an essential role of DNA-PKcs in the transcription-coupled repair Persistence and repair of bifunctional DNA adducts in tissues of laboratory animals exposed to 1,3-butadiene by inhalation.The Fanconi anemia protein, FANCG, binds to the ERCC1-XPF endonuclease via its tetratricopeptide repeats and the central domain of ERCC1.Cellular responses to Cisplatin-induced DNA damage.Using synthetic DNA interstrand crosslinks to elucidate repair pathways and identify new therapeutic targets for cancer chemotherapy.Multiple DNA binding domains mediate the function of the ERCC1-XPF protein in nucleotide excision repair.Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway Differential contributory roles of nucleotide excision and homologous recombination repair for enhancing cisplatin sensitivity in human ovarian cancer cells DNA repair mechanisms in dividing and non-dividing cells.Conformational determinants for the recruitment of ERCC1 by XPA in the nucleotide excision repair (NER) Pathway: structure and dynamics of the XPA binding motif UV-induced nuclear import of XPA is mediated by importin-α4 in an ATR-dependent manner Role of endonucleases XPF and XPG in nucleotide excision repair of platinated DNA and cisplatin/oxaliplatin cytotoxicity.The role of conformational selection in the molecular recognition of the wild type and mutants XPA67-80 peptides by ERCC1.The ERCC1 and ERCC4 (XPF) genes and gene products AKAP12 mediates PKA-induced phosphorylation of ATR to enhance nucleotide excision repair UHRF1 contributes to DNA damage repair as a lesion recognition factor and nuclease scaffold.PARP inhibition selectively increases sensitivity to cisplatin in ERCC1-low non-small cell lung cancer cells.Association between XRCC1 and ERCC1 single-nucleotide polymorphisms and the efficacy of concurrent radiochemotherapy in patients with esophageal squamous cell carcinoma.ERCC1: impact in multimodality treatment of upper gastrointestinal cancer.Regulation of endonuclease activity in human nucleotide excision repair.The Fanconi anaemia pathway orchestrates incisions at sites of crosslinked DNA.Affinity isolation and mass spectral analysis of 1,10-phenanthroline (OP)-stimulated UV-damaged-DNA binding proteins expressed in zebrafish (Danio rerio) embryos.DNA Repair Endonucleases: Physiological Roles and Potential as Drug Targets.ATR pathway inhibition is synthetically lethal in cancer cells with ERCC1 deficiency.[Enhanced cisplatin cytotoxicity by RNA interfering the excision repair cross-complementing gene 1 in lung cancer cell A549/DDP].Formation of Incision Complex in GG-NER ERCC1-XPF endonuclease-positioned to cut.Predictive biomarkers for combined chemotherapy with 5-fluorouracil and cisplatin in oro- and hypopharyngeal cancers.Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER

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The XPA-binding domain of ERCC1 is required for nucleotide excision repair but not other DNA repair pathways.

http://www.wikidata.org/entity/Q30919478

description

2009 nî lūn-bûn

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2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

The XPA-binding domain of ERCC ...... not other DNA repair pathways.

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The XPA-binding domain of ERCC ...... not other DNA repair pathways.

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type

label

The XPA-binding domain of ERCC ...... not other DNA repair pathways.

@ast

The XPA-binding domain of ERCC ...... not other DNA repair pathways.

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prefLabel

The XPA-binding domain of ERCC ...... not other DNA repair pathways.

@ast

The XPA-binding domain of ERCC ...... not other DNA repair pathways.

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JBC.M109.067538

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Journal of Biological Chemistry

P1476

The XPA-binding domain of ERCC ...... not other DNA repair pathways.

@en

P2093

Barbara Orelli

http://www.w3.org/2001/XMLSchema#string

Laura J Niedernhofer

http://www.w3.org/2001/XMLSchema#string

Oleg V Tsodikov

http://www.w3.org/2001/XMLSchema#string

Orlando D Schärer

http://www.w3.org/2001/XMLSchema#string

T Brooke McClendon

http://www.w3.org/2001/XMLSchema#string

Tom Ellenberger

http://www.w3.org/2001/XMLSchema#string

P2860

XPA versus ERCC1 as chemosensitising agents to cisplatin and mitomycin C in prostate cancer cells: role of ERCC1 in homologous recombination repair

Cockayne syndrome A and B proteins differentially regulate recruitment of chromatin remodeling and repair factors to stalled RNA polymerase II in vivo

ERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes

Functional and physical interactions between ERCC1 and MSH2 complexes for resistance to cis-diamminedichloroplatinum(II) in mammalian cells

Physical and functional interaction between the XPF/ERCC1 endonuclease and hRad52

Xeroderma pigmentosum group C protein complex is the initiator of global genome nucleotide excision repair

Crystal structure and DNA binding functions of ERCC1, a subunit of the DNA structure-specific endonuclease XPF-ERCC1

Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair

Drosophila MUS312 and the vertebrate ortholog BTBD12 interact with DNA structure-specific endonucleases in DNA repair and recombination

Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair

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6

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285

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2009-11-23T00:00:00Z

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40033358

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19940136

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2823511

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