Polymorphisms in the insulin-degrading enzyme gene are associated with type 2 diabetes in men from the NHLBI Framingham Heart Study. - Wikidata - awgldk - TriplyDB

Polymorphisms in the insulin-degrading enzyme gene are associated with type 2 diabetes in men from the NHLBI Framingham Heart Study.

Polymorphisms in the insulin-degrading enzyme gene are associated with type 2 diabetes in men from the NHLBI Framingham Heart Study.

http://www.wikidata.org/entity/Q30937160

about

Alternative translation initiation generates a novel isoform of insulin-degrading enzyme targeted to mitochondria Structure of substrate-free human insulin-degrading enzyme (IDE) and biophysical analysis of ATP-induced conformational switch of IDE Evidence that the gene encoding insulin degrading enzyme influences human lifespan Identification of the allosteric regulatory site of insulysin Yeast as a tractable genetic system for functional studies of the insulin-degrading enzyme.Association between TCF7L2 gene polymorphisms and susceptibility to type 2 diabetes mellitus: a large Human Genome Epidemiology (HuGE) review and meta-analysis A monomeric variant of insulin degrading enzyme (IDE) loses its regulatory properties Interleukin-6 increases the expression and activity of insulin-degrading enzyme.Genome-wide association study for feed efficiency and growth traits in U.S. beef cattle The therapeutic potential of metabolic hormones in the treatment of age-related cognitive decline and Alzheimer's disease.Disorder-specific effects of polymorphisms at opposing ends of the Insulin Degrading Enzyme gene.Redox regulation of insulin degradation by insulin-degrading enzyme.Deletion of the fission yeast homologue of human insulinase reveals a TORC1-dependent pathway mediating resistance to proteotoxic stress.Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid beta-protein.HHEX_23 AA Genotype Exacerbates Effect of Diabetes on Dementia and Alzheimer Disease: A Population-Based Longitudinal Study.Candidate genes for Alzheimer's disease are associated with individual differences in plasma levels of beta amyloid peptides in adults with Down syndrome.Acute Exercise Improves Insulin Clearance and Increases the Expression of Insulin-Degrading Enzyme in the Liver and Skeletal Muscle of Swiss Mice A new era for Type 2 diabetes genetics Hepatic cannabinoid receptor-1 mediates diet-induced insulin resistance via inhibition of insulin signaling and clearance in mice.Diabetes genes identified by genome-wide association studies are regulated in mice by nutritional factors in metabolically relevant tissues and by glucose concentrations in islets.IDE (rs6583817) polymorphism and type 2 diabetes differentially modify executive function in older adults IDE Gene Polymorphism Influences on BPSD in Mild Dementia of Alzheimer's Type Development of monoclonal antibodies and quantitative ELISAs targeting insulin-degrading enzyme.The Drosophila insulin-degrading enzyme restricts growth by modulating the PI3K pathway in a cell-autonomous manner.Insulin clearance: an underappreciated modulator of plasma insulin concentration.Insulin-degrading enzyme: new therapeutic target for diabetes and Alzheimer's disease?Alzheimer's disease and metabolic syndrome: A link from oxidative stress and inflammation to neurodegeneration.Structure, function, and regulation of insulin-degrading enzyme.Effects of ageing and experimental diabetes on insulin-degrading enzyme expression in male rat tissues.Bile acid TUDCA improves insulin clearance by increasing the expression of insulin-degrading enzyme in the liver of obese mice.Association between polymorphisms of the insulin-degrading enzyme gene and late-onset Alzheimer disease.Han ethnicity-specific type 2 diabetic treatment from traditional Chinese medicine?Quantitative trait locus dissection in congenic strains of the Goto-Kakizaki rat identifies a region conserved with diabetes loci in human chromosome 1q.A cladistic model of ACE sequence variation with implications for myocardial infarction, Alzheimer disease and obesity.Loss of renal SNX5 results in impaired IDE activity and insulin resistance in mice.Plaque-associated overexpression of insulin-degrading enzyme in the cerebral cortex of aged transgenic tg2576 mice with Alzheimer pathology.The effects of a cafeteria diet on insulin production and clearance in rats.

P2860

Q24300365-73884DE0-D193-4C0B-A95B-D9C65AA3B33C Q24317274-523DA0F9-783A-4CE9-8BFD-63E503A81E0B Q24336770-0EDF849F-61ED-455E-B8CA-AD45EFFDB426 Q27335211-E4D5EC0D-DD23-4365-9044-F5844B26E5BD Q27932546-F6A23B58-6EC6-4206-8D0E-E12B78BD802A Q33410679-63A1DB0F-1CCC-4164-A50A-1649226A1265 Q33543086-96A19DA6-0070-4006-B93F-9F2A6C072AB2 Q33587718-3EDC69B6-076A-4AA7-A758-F6EC12EAF24A Q33706506-6BB23255-F608-4D69-BD55-07591BEB3F2E Q33851630-815121ED-E028-4714-827C-F3582A8F6D89 Q34080209-94B50DA2-BAA7-4BC9-84D2-DE6D3DF779BF Q34712680-0D291C04-72A8-4358-8D5A-E3EEA60484B1 Q34797449-00F92A2F-F342-4479-B345-83AE18256AE1 Q35097358-62BB132C-4AE6-4766-90BC-9AE5417E92E0 Q35691000-E45BC86C-EE22-49B0-B259-13C823171519 Q36037548-9139ABFC-1577-4D81-B41B-D08302A93915 Q36088453-B1DE61F5-A981-4AB7-83E1-F0C6EFF96C9B Q36237867-76CD9517-9465-4A69-8139-48113F27D8DA Q36351511-3D8B23EB-637B-45D2-88B1-A878F4790711 Q36877444-5C495DD6-5C80-4ABA-944D-D3424B9D933A Q36920191-1F4939E5-937C-43B8-8142-ADAC7FECDEFD Q37166278-298A487C-225C-4BC2-AF90-FFC05E3F6E54 Q37402080-EC5873B8-EBD7-4F6B-856F-9F6ED8BFFD80 Q37635355-D8FA996B-51D4-4EEE-8027-9E1EC71F7468 Q38845394-4F076C17-4352-44FD-A882-6AEA21D301B0 Q38869928-0EFC024D-CF2C-48CE-9D66-01E91DB91037 Q39398227-2DA7D8E3-86FF-4BA9-87D5-A9EF27CFBA44 Q40782441-14D9B0D9-58E7-4DBB-8750-105A5BE6EA80 Q41190059-CF3A5054-DE6B-40FF-9E5A-38F37D3886EA Q43620015-76252571-B144-4830-9B78-95BD440B255E Q44446906-D80C10E6-978B-47F6-9012-F4EF96B929B1 Q44806080-8E9C1161-D266-47B8-AE4B-5D27EA2E17A6 Q44987615-C7A7911E-FCC2-4FBD-825F-31CB2D6B62E8 Q45059091-35FFBEB4-3946-4F84-B9BC-D2567842F34A Q45071260-62D403D5-566A-4474-8B0F-0D0AB7D785ED Q48404243-69FD99EA-A5BA-4335-978A-9910B39F81B7 Q51377992-1F2DFC82-C14C-4CBC-909D-93E8B3BF0154

P2860

Polymorphisms in the insulin-degrading enzyme gene are associated with type 2 diabetes in men from the NHLBI Framingham Heart Study.

http://www.wikidata.org/entity/Q30937160

description

2003 nî lūn-bûn

@nan

2003 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2003年の論文

@ja

2003年論文

@yue

2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

name

Polymorphisms in the insulin-d ...... NHLBI Framingham Heart Study.

@ast

Polymorphisms in the insulin-d ...... NHLBI Framingham Heart Study.

@en

type

label

Polymorphisms in the insulin-d ...... NHLBI Framingham Heart Study.

@ast

Polymorphisms in the insulin-d ...... NHLBI Framingham Heart Study.

@en

prefLabel

Polymorphisms in the insulin-d ...... NHLBI Framingham Heart Study.

@ast

Polymorphisms in the insulin-d ...... NHLBI Framingham Heart Study.

@en

P1433

Q30937160-F1B7EE48-529D-4744-9D89-D09D8D1B9D86

P1476

Q30937160-B44335A5-A560-4636-B3B9-5C90DAE7878A

P2093

Q30937160-24F4BF59-83E2-4E47-8076-961C02E007A7

Q30937160-334A82A9-CBC3-4722-A284-E5080E4DE7BA

Q30937160-4697B0D7-C690-41C0-B976-31F628E5646C

Q30937160-54ED83D0-5905-4466-83BD-BD20213EFD9A

Q30937160-824DE9E0-1A91-453B-A648-97AC59947B46

Q30937160-82D7BD26-9D18-4D66-AF03-3FC5E7460A37

Q30937160-B32A6B0B-C607-4EF0-B231-9189725089F2

Q30937160-B9AC4055-B975-48A2-8540-00AF4DB5E6B0

Q30937160-BDEED4D6-F025-4FFF-85B9-D0EB83700CDA

Q30937160-DD8A6C29-FCBD-418D-8AFD-BC91AE36F338

P304

Q30937160-5073DB89-9C5A-4596-85A8-794D0820F8B3

P31

Q30937160-DC8E8468-B65F-4463-B0AF-EF9680724C15

P356

Q30937160-C1944E27-96B6-4EA7-AF97-87A782E4F5E0

P407

Q30937160-4F42C4E5-ADB2-40BB-A9DD-887654E2916F

P433

Q30937160-B14DA257-10F9-4A1A-8883-5B7F1B3F0ADB

P478

Q30937160-CD5B9EFC-44F8-403A-91BD-2CC043FE1505

P50

Q30937160-2C5C2325-5575-4375-ABD3-4941910FA892

Q30937160-B266D625-7D2C-471C-9502-07B152A9356E

Q30937160-CF89A313-E9EA-4628-9494-50ADC1ED053C

P577

Q30937160-A2E96755-4352-4CD6-8507-BC4C9685E7D5

P5875

Q30937160-F9B8234B-18EA-4FC5-BB78-16B5D7DA2772

P698

Q30937160-952FBBE5-344B-436E-9612-AFF2FD9BACAD

P921

Q30937160-7FCBB804-807C-4393-BCAC-1129CAF71226

Q30937160-E287CD31-D29E-4403-B32F-1B28F0BF2DD3

P356

DIABETES.52.6.1562

P1433

P1476

Polymorphisms in the insulin-d ...... NHLBI Framingham Heart Study.

@en

P2093

Alan Herbert

http://www.w3.org/2001/XMLSchema#string

Carolien I Panhuysen

http://www.w3.org/2001/XMLSchema#string

Christina M Shoemaker

http://www.w3.org/2001/XMLSchema#string

Chunyu Liu

http://www.w3.org/2001/XMLSchema#string

Jeannine Volcjak

http://www.w3.org/2001/XMLSchema#string

Jun Liu

http://www.w3.org/2001/XMLSchema#string

L Adrienne Cupples

http://www.w3.org/2001/XMLSchema#string

Larry D Atwood

http://www.w3.org/2001/XMLSchema#string

NHLBI Framingham Heart Study

http://www.w3.org/2001/XMLSchema#string

Peter Wilson

http://www.w3.org/2001/XMLSchema#string

P304

1562-1567

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.2337/DIABETES.52.6.1562

http://www.w3.org/2001/XMLSchema#string

P407

P433

6

http://www.w3.org/2001/XMLSchema#string

P478

52

http://www.w3.org/2001/XMLSchema#string

P50

Nancy L Heard-Costa

Serkalem Demissie

P577

2003-06-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

7155992

http://www.w3.org/2001/XMLSchema#string

P698

12765971

http://www.w3.org/2001/XMLSchema#string

P921

type-2 diabetes