about
Identifying tumor cell growth inhibitors by combinatorial chemistry and zebrafish assaysOptimization of the Ugi reaction using parallel synthesis and automated liquid handlingIsocyanide-Based Multicomponent Reactions for the Synthesis of HeterocyclesFocusing on shared subpockets - new developments in fragment-based drug discoveryDiscovery, synthesis, and structure-based optimization of a series of N-(tert-butyl)-2-(N-arylamido)-2-(pyridin-3-yl) acetamides (ML188) as potent noncovalent small molecule inhibitors of the severe acute respiratory syndrome coronavirus (SARS-CoV)Expedient synthesis of highly potent antagonists of inhibitor of apoptosis proteins (IAPs) with unique selectivity for ML-IAPHighly stereoselective synthesis of natural-product-like hybrids by an organocatalytic/multicomponent reaction sequence.Higher-order multicomponent reactions: beyond four reactants.Multidimensional nano-HPLC coupled with tandem mass spectrometry for analyzing biotinylated proteins.Synthesis of multivalent aminoglycoside mimics via the Ugi multicomponent reaction.Parallel and four-step synthesis of natural-product-inspired scaffolds through modular assembly and divergent cyclization.A chemoselective Ugi-type reaction in water using TMSCN as a functional isonitrile equivalent: generation of heteroaromatic molecular diversity.Evaluation of "credit card" libraries for inhibition of HIV-1 gp41 fusogenic core formationMicrowave-assisted synthesis of a 3-aminoimidazo[1,2-a]-pyridine/pyrazine library by fluorous multicomponent reactions and subsequent cross-coupling reactionsApplications of multicomponent reactions to the synthesis of diverse heterocyclic scaffoldsStrategies for innovation in multicomponent reaction design.Fluorous parallel synthesis of a piperazinedione-fused tricyclic compound libraryThree-component synthesis of benzo[b][1,5]thiazepines via coupling-addition-cyclocondensation sequence.Three-component asymmetric catalytic Ugi reaction--concinnity from diversity by substrate-mediated catalyst assembly.Boron-based dipolar multicomponent reactions: simple generation of substituted aziridines, oxazolidines and pyrrolidines.Solid-phase synthesis of N-substituted pyrrolidinone-tethered N-substituted piperidines via Ugi reaction.An Efficient Boric Acid Mediated Preparation of α-Hydroxyamides.1,4-Thienodiazepine-2,5-diones via MCR (II): scaffold hopping by Gewald and Ugi-deprotection-cyclization strategyStudies toward a library of tetrahydrofurans: click and MCR products of mono- and bis-tetrahydrofuransDiastereoselective three-component synthesis of β-amino carbonyl compounds using diazo compounds, boranes, and acyl imines under catalyst-free conditions.Low-basicity 5-HT7 Receptor Agonists Synthesized Using the van Leusen Multicomponent ProtocolA practical and efficient approach to imidazo[1,2-a]pyridine-fused isoquinolines through the post-GBB transformation strategy.Exploiting the Divalent Nature of Isonitriles: a novel Pictet-Spengler Amidination process.Diversity-oriented synthesis leads to an effective class of bifunctional linchpins uniting anion relay chemistry (ARC) with benzyne reactivity.New tricks of well-known aminoazoles in isocyanide-based multicomponent reactions and antibacterial activity of the compounds synthesized.Design and discovery of novel monastrol-1,3,5-triazines as potent anti-breast cancer agent via attenuating Epidermal Growth Factor Receptor tyrosine kinase.Multicomponent reaction design in the quest for molecular complexity and diversity.Thiourea dioxide promoted efficient organocatalytic one-pot synthesis of a library of novel heterocyclic compounds.Two step syntheses of fused quinoxaline-benzodiazepines and bis-benzodiazepinesDevelopment of a 2-aza-Cope-[3 + 2] dipolar cycloaddition strategy for the synthesis of quaternary proline scaffolds.Three-component reaction discovery enabled by mass spectrometry of self-assembled monolayersN-[(2-Hydr-oxy-1-naphthyl)(3-nitro-phenyl)meth-yl]acetamideFacile synthesis of 1H-imidazo[1,2-b]pyrazoles via a sequential one-pot synthetic approachIdentification of a 3-aminoimidazo[1,2-a]pyridine inhibitor of HIV-1 reverse transcriptase.Synthesis of peptoid based small molecular gelators by a multiple component reaction.
P2860
Q21092150-2A8D8B96-CA83-4121-ACE9-39299AAD2D0AQ24652546-2F7345DE-8A6B-4DFA-9551-0F3F31D25D9FQ26772038-571F5B85-1C3F-4F1F-85C2-6E6FB0E0F938Q26795719-CCB0A3AC-77AF-404A-91D4-B96373DD7D74Q27675449-20531640-BA92-44FA-8D70-09CE11D2EBE9Q28283505-947A5229-A957-4F39-9D80-772F62C6DA24Q30316563-2CC7CD61-6B5A-4C8D-A636-A17EF8D809B6Q30317877-4CC459D2-AC18-4C5F-9992-DFE777CA8E32Q30318086-FB3B4B51-0FB1-4B72-A81F-386905AEDE26Q30320244-4AC32863-F82B-4B38-9CD2-08F70209560DQ30394831-3FC75A3C-3875-42C8-A1A5-412C6FD964C6Q30574940-BF413681-8D02-4258-84C7-3980B7B90686Q33249271-19295A60-2469-4B1D-8911-EE90E9E18F55Q33342246-32540ABA-33E2-45A6-8C08-E3AC2DCDF0DAQ33398592-C6806A1F-DE68-4321-9207-8AFC19A7DBA8Q33403566-7C503BFE-3E26-4C6A-AD46-6AC91C5F2CF5Q33420012-985999DC-C96B-47B3-8ECD-E513258EE1D7Q33531429-8A06F40E-453F-4429-9DE8-A6E1831D3BA7Q33566408-EF24C840-89AA-4C1A-AF58-2BA5B5A9A423Q33589911-5B11AB7D-478C-426A-9208-8900A65A32D4Q33596209-5B1E49CE-6095-42F6-9268-7982CA27C676Q33596884-4490473A-C7DC-483A-9FE9-49ECB28C4EBBQ33603523-ACBC5815-6191-454F-BEB4-E53908CBE566Q33627928-08AEDE5B-5A71-43AF-9C6E-2EB88B39AC78Q33662369-1C3E2383-12D9-4A0F-AB22-B3FBBF4F3ED1Q33685407-235D4AB2-3697-45FC-BC76-4105FBD6891FQ33692158-CA988D05-9AA2-4ACA-9119-465829300353Q33773093-E10F7299-7711-45D2-BD81-9F9BDF72C152Q33796277-6C4B911E-719D-4D63-8E80-B4C1D63EDBE0Q33824188-CD723E0A-D13C-4064-85E3-3DBDB3A14D1FQ33918829-154C9019-7EAB-45D7-8788-327CCCBA0AFAQ33944558-70EA2856-D951-43F7-A447-1A0D288BAA29Q34006957-81B64610-6BE9-453B-910A-164D1E013EB2Q34051436-BD5A68F3-8FB1-4366-A861-7E8EEFD8C1E7Q34088542-70B609D3-F785-4BE8-93D9-CB5D5FC27857Q34101287-4473F644-BDE9-4F0B-B0C3-5ED895F7D006Q34262658-31999ADF-C8A9-4CDB-B3A0-1AB475DF9ADFQ34463349-78D39B80-728B-44EE-8C48-F846D075C5C5Q34508801-6161DC97-AC66-42C0-B509-EC3C7199C48EQ34647100-E2B137CC-A4EF-4093-A4C8-5614212E126B
P2860
description
2000 nî lūn-bûn
@nan
2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Multicomponent Reactions with Isocyanides.
@ast
Multicomponent Reactions with Isocyanides.
@en
type
label
Multicomponent Reactions with Isocyanides.
@ast
Multicomponent Reactions with Isocyanides.
@en
prefLabel
Multicomponent Reactions with Isocyanides.
@ast
Multicomponent Reactions with Isocyanides.
@en
P1476
Multicomponent Reactions with Isocyanides
@en
P2093
P304
P356
10.1002/1521-3773(20000915)39:18<3168::AID-ANIE3168>3.0.CO;2-U
P407
P50
P577
2000-09-01T00:00:00Z