The integrin alpha(v)beta(3-5) ligand MFG-E8 is a p63/p73 target gene in triple-negative breast cancers but exhibits suppressive functions in ER(+) and erbB2(+) breast cancers.
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Inhibition of phosphatidylcholine-specific phospholipase C results in loss of mesenchymal traits in metastatic breast cancer cells.New blocking antibodies impede adhesion, migration and survival of ovarian cancer cells, highlighting MFGE8 as a potential therapeutic target of human ovarian carcinoma.p63 is a suppressor of tumorigenesis and metastasis interacting with mutant p53.Wilms' tumor gene 1 regulates p63 and promotes cell proliferation in squamous cell carcinoma of the head and neckMalignant ovarian tumors with induced expression of carbonyl reductase show spontaneous regression.MFG-E8 activates proliferation of vascular smooth muscle cells via integrin signaling.TAp73 is required for macrophage-mediated innate immunity and the resolution of inflammatory responses.Noninvasive monitoring of orthotopic glioblastoma therapy response using RGD-conjugated iron oxide nanoparticles.Immune mediators in the tumor microenvironment of prostate cancer.MFG-E8 overexpression promotes colorectal cancer progression via AKT/MMPs signalling.MFG-E8 expression for progression of oral squamous cell carcinoma and for self-clearance of apoptotic cells.Milk fat globule epidermal growth factor 8 serves a novel biomarker of opisthorchiasis-associated cholangiocarcinoma.MFG-E8/lactadherin regulates cyclins D1/D3 expression and enhances the tumorigenic potential of mammary epithelial cells.Recombinant milk fat globule-EGF factor-8 reduces oxidative stress via integrin β3/nuclear factor erythroid 2-related factor 2/heme oxygenase pathway in subarachnoid hemorrhage rats.MFG-E8 Is Critical for Embryonic Stem Cell-Mediated T Cell Immunomodulation.p63 Expression is a prognostic factor in colorectal cancer.Milk Fat Globule-Epidermal Growth Factor-8 Pretreatment Attenuates Apoptosis and Inflammation via the Integrin-β3 Pathway after Surgical Brain Injury in Rats.Ensemble outlier detection and gene selection in triple-negative breast cancer data.
P2860
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P2860
The integrin alpha(v)beta(3-5) ligand MFG-E8 is a p63/p73 target gene in triple-negative breast cancers but exhibits suppressive functions in ER(+) and erbB2(+) breast cancers.
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2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
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2010年学术文章
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2010年学术文章
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2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
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2010年學術文章
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name
The integrin alpha(v)beta(3-5) ...... ) and erbB2(+) breast cancers.
@ast
The integrin alpha(v)beta(3-5) ...... ) and erbB2(+) breast cancers.
@en
type
label
The integrin alpha(v)beta(3-5) ...... ) and erbB2(+) breast cancers.
@ast
The integrin alpha(v)beta(3-5) ...... ) and erbB2(+) breast cancers.
@en
prefLabel
The integrin alpha(v)beta(3-5) ...... ) and erbB2(+) breast cancers.
@ast
The integrin alpha(v)beta(3-5) ...... ) and erbB2(+) breast cancers.
@en
P2093
P2860
P1433
P1476
The integrin alpha(v)beta(3-5) ...... ) and erbB2(+) breast cancers.
@en
P2093
Chuanwei Yang
Dejun Shen
Dennis Sgroi
Emmett V Schmidt
Karen S Anderson
Leif W Ellisen
Nicole Forster
Shyamala Maheswaran
P2860
P304
P356
10.1158/0008-5472.CAN-10-1471
P407
P577
2010-12-02T00:00:00Z