NADPH oxidase 2-derived reactive oxygen species mediate FFAs-induced dysfunction and apoptosis of β-cells via JNK, p38 MAPK and p53 pathways.
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The beneficial role of vitamin D in obesity: possible genetic and cell signaling mechanismsCytochrome P450 3A1 mediates 2,2',4,4'-tetrabromodiphenyl ether-induced reduction of spermatogenesis in adult ratsKinase Signaling in Apoptosis Induced by Saturated Fatty Acids in Pancreatic β-CellsThe role of the p53 tumor suppressor in metabolism and diabetesInvolvement of the up-regulated FoxO1 expression in follicular granulosa cell apoptosis induced by oxidative stressTRB3 is involved in free fatty acid-induced INS-1-derived cell apoptosis via the protein kinase C δ pathwayTCF2 attenuates FFA-induced damage in islet β-cells by regulating production of insulin and ROS.Differential regulation of placental amino acid transport by saturated and unsaturated fatty acidsInvolvement of dynamin-related protein 1 in free fatty acid-induced INS-1-derived cell apoptosisOleic, linoleic and linolenic acids increase ros production by fibroblasts via NADPH oxidase activation.Advanced glycation end products induce human corneal epithelial cells apoptosis through generation of reactive oxygen species and activation of JNK and p38 MAPK pathways.Friendly, and not so friendly, roles of Rac1 in islet β-cell function: lessons learnt from pharmacological and molecular biological approachesPalmitate Inhibits SIRT1-Dependent BMAL1/CLOCK Interaction and Disrupts Circadian Gene Oscillations in Hepatocytes.p38 MAPK Is Activated but Does Not Play a Key Role during Apoptosis Induction by Saturated Fatty Acid in Human Pancreatic β-Cells.NOX2 As a Target for Drug Development: Indications, Possible Complications, and Progress.NADPH oxidase NOX2 defines a new antagonistic role for reactive oxygen species and cAMP/PKA in the regulation of insulin secretion.Palmitate induces ER calcium depletion and apoptosis in mouse podocytes subsequent to mitochondrial oxidative stressFenugreek lactone attenuates palmitate-induced apoptosis and dysfunction in pancreatic β-cellsGallic Acid Induces a Reactive Oxygen Species-Provoked c-Jun NH2-Terminal Kinase-Dependent Apoptosis in Lung FibroblastsActivation of the mitochondrial ATP-sensitive K+ channel reduces apoptosis of spleen mononuclear cells induced by hyperlipidemia.Macrophage glucose-6-phosphate dehydrogenase stimulates proinflammatory responses with oxidative stress.A novel mechanism by which SDF-1β protects cardiac cells from palmitate-induced endoplasmic reticulum stress and apoptosis via CXCR7 and AMPK/p38 MAPK-mediated interleukin-6 generation.Interaction between cytokines and inflammatory cells in islet dysfunction, insulin resistance and vascular diseaseOleic acid increases synthesis and secretion of VEGF in rat vascular smooth muscle cells: role of oxidative stress and impairment in obesity.NADPH oxidase in brain injury and neurodegenerative disordersIs p53 Involved in Tissue-Specific Insulin Resistance Formation?Supplementation with Phycocyanobilin, Citrulline, Taurine, and Supranutritional Doses of Folic Acid and Biotin-Potential for Preventing or Slowing the Progression of Diabetic Complications.The mechanisms linking adiposopathy to type 2 diabetes.Link between PI3K/AKT/PTEN Pathway and NOX Proteinin Diseases.Certain Diet and Lifestyle May Contribute to Islet β-cells Protection in Type-2 Diabetes via the Modulation of Cellular PI3K/AKT Pathway.P38 plays an important role in glucolipotoxicity-induced apoptosis in INS-1 cells.TRPM2-mediated rise in mitochondrial Zn(2+) promotes palmitate-induced mitochondrial fission and pancreatic β-cell death in rodents.Inhibition of tumor suppressor p53 preserves glycation-serum induced pancreatic beta-cell demise.Saturated free fatty acids induce cholangiocyte lipoapoptosis.Evidence for paracrine/autocrine regulation of GLP-1-producing cells.High glucose induces mitochondrial p53 phosphorylation by p38 MAPK in pancreatic RINm5F cells.NADPH oxidase 2 plays a critical role in dysfunction and apoptosis of pancreatic β-cells induced by very low-density lipoprotein.NOX, NOX Who is There? The Contribution of NADPH Oxidase One to Beta Cell Dysfunction.Palmitate induces reactive oxygen species production and β-cell dysfunction by activating nicotinamide adenine dinucleotide phosphate oxidase through Src signalingThe p66(Shc) redox adaptor protein is induced by saturated fatty acids and mediates lipotoxicity-induced apoptosis in pancreatic beta cells.
P2860
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P2860
NADPH oxidase 2-derived reactive oxygen species mediate FFAs-induced dysfunction and apoptosis of β-cells via JNK, p38 MAPK and p53 pathways.
description
2010 nî lūn-bûn
@nan
2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
NADPH oxidase 2-derived reacti ...... NK, p38 MAPK and p53 pathways.
@ast
NADPH oxidase 2-derived reacti ...... NK, p38 MAPK and p53 pathways.
@en
type
label
NADPH oxidase 2-derived reacti ...... NK, p38 MAPK and p53 pathways.
@ast
NADPH oxidase 2-derived reacti ...... NK, p38 MAPK and p53 pathways.
@en
prefLabel
NADPH oxidase 2-derived reacti ...... NK, p38 MAPK and p53 pathways.
@ast
NADPH oxidase 2-derived reacti ...... NK, p38 MAPK and p53 pathways.
@en
P2093
P2860
P1433
P1476
NADPH oxidase 2-derived reacti ...... NK, p38 MAPK and p53 pathways.
@en
P2093
Huiping Yuan
Jianzhong Xi
Weiqing Tang
Xiaoyong Zhang
Xiuqing Huang
Yonggang Lu
P2860
P304
P356
10.1371/JOURNAL.PONE.0015726
P407
P577
2010-12-29T00:00:00Z