Highly sensitive in vitro selections for DNA-linked synthetic small molecules with protein binding affinity and specificity.
about
Highly specific, bisubstrate-competitive Src inhibitors from DNA-templated macrocyclesDNA-templated organic synthesis and selection of a library of macrocyclesTranslating DNA into synthetic moleculesEncoded self-assembling chemical libraries.Interaction-dependent PCR: identification of ligand-target pairs from libraries of ligands and libraries of targets in a single solution-phase experiment.Translation of DNA into a library of 13,000 synthetic small-molecule macrocycles suitable for in vitro selection.Reactivity-dependent PCR: direct, solution-phase in vitro selection for bond formation.An in vitro translation, selection and amplification system for peptide nucleic acidsIn vitro selection of a DNA-templated small-molecule library reveals a class of macrocyclic kinase inhibitorsPhotoaffinity labeling of transcription factors by DNA-templated crosslinking.Small-molecule discovery from DNA-encoded chemical libraries.Self-made phage libraries with heterologous inserts in the Mtd of Bordetella bronchiseptica.Carbonic anhydrase as a model for biophysical and physical-organic studies of proteins and protein-ligand binding.DNA-guided display of proteins and protein ligands for the interrogation of biology.Oligonucleotide-templated chemical reactions: pushing the boundaries of a nature-inspired process.A target-triggered exponential amplification-based DNAzyme biosensor for ultrasensitive detection of folate receptors.Development and initial application of a hybridization-independent, DNA-encoded reaction discovery system compatible with organic solvents.Coupling of background reduction with rolling circle amplification for highly sensitive protein detection via terminal protection of small molecule-linked DNA.Selection of DNA-encoded small molecule libraries against unmodified and non-immobilized protein targets.Conjugation of DNA with Biomolecules and NanoparticlesSynthesis of Nucleic Acid-Peptide Conjugates Targeted to Proteins
P2860
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P2860
Highly sensitive in vitro selections for DNA-linked synthetic small molecules with protein binding affinity and specificity.
description
2003 nî lūn-bûn
@nan
2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Highly sensitive in vitro sele ...... ding affinity and specificity.
@ast
Highly sensitive in vitro sele ...... ding affinity and specificity.
@en
type
label
Highly sensitive in vitro sele ...... ding affinity and specificity.
@ast
Highly sensitive in vitro sele ...... ding affinity and specificity.
@en
prefLabel
Highly sensitive in vitro sele ...... ding affinity and specificity.
@ast
Highly sensitive in vitro sele ...... ding affinity and specificity.
@en
P2093
P356
P1476
Highly sensitive in vitro sele ...... ding affinity and specificity.
@en
P2093
David R Liu
Jeffrey B Doyon
Thomas M Snyder
P304
12372-12373
P356
10.1021/JA036065U
P407
P577
2003-10-01T00:00:00Z