Talin1 is critical for force-dependent reinforcement of initial integrin-cytoskeleton bonds but not tyrosine kinase activation - Wikidata - awgldk - TriplyDB

Talin1 is critical for force-dependent reinforcement of initial integrin-cytoskeleton bonds but not tyrosine kinase activation

Talin1 is critical for force-dependent reinforcement of initial integrin-cytoskeleton bonds but not tyrosine kinase activation

http://www.wikidata.org/entity/Q31018295

about

Integrins β1 and β3 exhibit distinct dynamic nanoscale organizations inside focal adhesions Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle Dissecting cell adhesion architecture using advanced imaging techniques Integrin cytoplasmic tail interactions Vinculin and metavinculin: oligomerization and interactions with F-actin Integrin-dependent activation of the JNK signaling pathway by mechanical stress Interplay between cytoskeletal stresses and cell adaptation under chronic flow Rap1 can bypass the FAK-Src-Paxillin cascade to induce cell spreading and focal adhesion formation Vinculin controls talin engagement with the actomyosin machinery.Reinforcement versus fluidization in cytoskeletal mechanoresponsiveness Structure of a Complete Integrin Ectodomain in a Physiologic Resting State and Activation and Deactivation by Applied Forces Actomyosin stress fiber mechanosensing in 2D and 3D Mechanotransduction in vivo by repeated talin stretch-relaxation events depends upon vinculin Cell adaptive response to extracellular matrix density is controlled by ICAP-1-dependent beta1-integrin affinity Coordinated integrin activation by actin-dependent force during T-cell migration Bi-directional signaling: extracellular matrix and integrin regulation of breast tumor progression Kinetic model for lamellipodal actin-integrin 'clutch' dynamics.Vinculin controls focal adhesion formation by direct interactions with talin and actin.Loss of PIP5KIgamma, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes.Molecular dynamics study of talin-vinculin binding.Clustering of alpha(5)beta(1) integrins determines adhesion strength whereas alpha(v)beta(3) and talin enable mechanotransduction The constant beat: cardiomyocytes adapt their forces by equal contraction upon environmental stiffening Integrin-dependent force transmission to the extracellular matrix by α-actinin triggers adhesion maturation Diverse integrin adhesion stoichiometries caused by varied actomyosin activity.Slipping or gripping? Fluorescent speckle microscopy in fish keratocytes reveals two different mechanisms for generating a retrograde flow of actin.Rigidity sensing at the leading edge through alphavbeta3 integrins and RPTPalpha.How force might activate talin's vinculin binding sites: SMD reveals a structural mechanism.A microfluidic system with optical laser tweezers to study mechanotransduction and focal adhesion recruitment.Cell adhesion strengthening: contributions of adhesive area, integrin binding, and focal adhesion assembly Vinculin potentiates E-cadherin mechanosensing and is recruited to actin-anchored sites within adherens junctions in a myosin II-dependent manner.A molecular dynamics investigation of vinculin activation.FAK is required for Schwann cell spreading on immature basal lamina to coordinate the radial sorting of peripheral axons with myelination Talin1 has unique expression versus talin 2 in the heart and modifies the hypertrophic response to pressure overload.Talin B is required for force transmission in morphogenesis of Dictyostelium.Mammary gland ECM remodeling, stiffness, and mechanosignaling in normal development and tumor progression The physical interaction of myoblasts with the microenvironment during remodeling of the cytoarchitecture.Actin flow and talin dynamics govern rigidity sensing in actin-integrin linkage through talin extension.Coordinate regulation of fibronectin matrix assembly by the plasminogen activator system and vitronectin in human osteosarcoma cells.Lipid binding promotes oligomerization and focal adhesion activity of vinculin Cell signaling experiments driven by optical manipulation

P2860

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P2860

Talin1 is critical for force-dependent reinforcement of initial integrin-cytoskeleton bonds but not tyrosine kinase activation

http://www.wikidata.org/entity/Q31018295

description

2003 nî lūn-bûn

@nan

2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2003年の論文

@ja

2003年論文

@yue

2003年論文

@zh-hant

2003年論文

@zh-hk

2003年論文

@zh-mo

2003年論文

@zh-tw

2003年论文

@wuu

name

Talin1 is critical for force-d ...... not tyrosine kinase activation

@ast

Talin1 is critical for force-d ...... not tyrosine kinase activation

@en

type

label

Talin1 is critical for force-d ...... not tyrosine kinase activation

@ast

Talin1 is critical for force-d ...... not tyrosine kinase activation

@en

prefLabel

Talin1 is critical for force-d ...... not tyrosine kinase activation

@ast

Talin1 is critical for force-d ...... not tyrosine kinase activation

@en

P1433

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P356

P1433

Journal of Cell Biology

P1476

Talin1 is critical for force-d ...... not tyrosine kinase activation

@en

P2093

David R Critchley

http://www.w3.org/2001/XMLSchema#string

Deborah H Sutton

http://www.w3.org/2001/XMLSchema#string

Grégory Giannone

http://www.w3.org/2001/XMLSchema#string

Guoying Jiang

http://www.w3.org/2001/XMLSchema#string

Michael P Sheetz

http://www.w3.org/2001/XMLSchema#string

P2860

Conformation, localization, and integrin binding of talin depend on its interaction with phosphoinositides

Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism

Cell migration: a physically integrated molecular process

Paxillin interactions

Filamins as integrators of cell mechanics and signalling

Two-piconewton slip bond between fibronectin and the cytoskeleton depends on talin

Cell locomotion and focal adhesions are regulated by substrate flexibility

Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substrates

SRC catalytic but not scaffolding function is needed for integrin-regulated tyrosine phosphorylation, cell migration, and cell spreading.

Localization of an integrin binding site to the C terminus of talin.

P304

409-419

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1083/JCB.200302001

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P407

P433

2

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P478

163

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P577

2003-10-01T00:00:00Z

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P5875

9038602

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P698

14581461

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P932

2173516

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