An analysis of genetic toxicity, reproductive and developmental toxicity, and carcinogenicity data: I. Identification of carcinogens using surrogate endpoints.
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A Systematic Review of Carcinogenic Outcomes and Potential Mechanisms from Exposure to 2,4-D and MCPA in the EnvironmentThe biomechanisms of metal and metal-oxide nanoparticles' interactions with cellsRetrospective analysis of the mutagenicity/genotoxicity data of the cosmetic ingredients present on the Annexes of the Cosmetic EU legislation (2000-12).Toxicological and clinical computational analysis and the US FDA/CDER.Understanding genetic toxicity through data mining: the process of building knowledge by integrating multiple genetic toxicity databases.An investigation into pharmaceutically relevant mutagenicity data and the influence on Ames predictive potential.Development of a high-throughput Gaussia luciferase reporter assay for the activation of the GADD45a gene by mutagens, promutagens, clastogens, and aneugens.Genetic toxicology in the 21st century: reflections and future directions.Global structure-activity relationship model for nonmutagenic carcinogens using virtual ligand-protein interactions as model descriptors.In silico approaches to explore toxicity end points: issues and concerns for estimating human health effects.In vitro approaches to develop weight of evidence (WoE) and mode of action (MoA) discussions with positive in vitro genotoxicity results.MultiCASE Expert Systems and the REACH Initiative.New and emerging technologies for genetic toxicity testing.Improvements in the reliability of in vitro genotoxicity testing.(Q)SAR modeling and safety assessment in regulatory review.International regulatory requirements for genotoxicity testing for pharmaceuticals used in human medicine, and their impurities and metabolites.Regulatory Acceptance of Alternative Methods in the Development and Approval of Pharmaceuticals.Effectiveness of CASE Ultra Expert System in Evaluating Adverse Effects of Drugs.Comet assay in reconstructed 3D human epidermal skin models--investigation of intra- and inter-laboratory reproducibility with coded chemicals.Analysis of 75 marketed pharmaceuticals using the GADD45a-GFP 'GreenScreen HC' genotoxicity assay.Mutagenicity testing for chemical risk assessment: update of the WHO/IPCS Harmonized Scheme.Cytotoxicity in cultured mammalian cells is a function of the method used to estimate it.In Silico Screening of Chemicals for Genetic Toxicity Using MDL-QSAR, Nonparametric Discriminant Analysis, E-State, Connectivity, and Molecular Property Descriptors.Combined Use of MC4PC, MDL-QSAR, BioEpisteme, Leadscope PDM, and Derek for Windows Software to Achieve High-Performance, High-Confidence, Mode of Action-Based Predictions of Chemical Carcinogenesis in Rodents.The Consultancy Activity on In Silico Models for Genotoxic Prediction of Pharmaceutical Impurities.In silico toxicology: comprehensive benchmarking of multi-label classification methods applied to chemical toxicity data.Navigating through the minefield of read-across tools: A review of in silico tools for grouping
P2860
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P2860
An analysis of genetic toxicity, reproductive and developmental toxicity, and carcinogenicity data: I. Identification of carcinogens using surrogate endpoints.
description
2005 nî lūn-bûn
@nan
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
An analysis of genetic toxicit ...... ens using surrogate endpoints.
@ast
An analysis of genetic toxicit ...... ens using surrogate endpoints.
@en
type
label
An analysis of genetic toxicit ...... ens using surrogate endpoints.
@ast
An analysis of genetic toxicit ...... ens using surrogate endpoints.
@en
prefLabel
An analysis of genetic toxicit ...... ens using surrogate endpoints.
@ast
An analysis of genetic toxicit ...... ens using surrogate endpoints.
@en
P2093
P1476
An analysis of genetic toxicit ...... ens using surrogate endpoints.
@en
P2093
Edwin J Matthews
Joseph F Contrera
Michael C Cimino
Naomi L Kruhlak
R Daniel Benz
P356
10.1016/J.YRTPH.2005.11.003
P407
P577
2005-12-28T00:00:00Z