The human amyloid-beta precursor protein770 mutation V717F generates peptides longer than amyloid-beta-(40-42) and flocculent amyloid aggregates.
about
Identification of a new presenilin-dependent zeta-cleavage site within the transmembrane domain of amyloid precursor protein.Neuropathology and amyloid-β spectrum in a bapineuzumab immunotherapy recipient.Arizona Study of Aging and Neurodegenerative Disorders and Brain and Body Donation Program.Presenilin-1 280Glu-->Ala mutation alters C-terminal APP processing yielding longer abeta peptides: implications for Alzheimer's diseaseAmyloid precursor protein transgenic mouse models and Alzheimer's disease: understanding the paradigms, limitations, and contributions.Mutations in amyloid precursor protein affect its interactions with presenilin/gamma-secretase.Antibody responses, amyloid-beta peptide remnants and clinical effects of AN-1792 immunization in patients with AD in an interrupted trial.Familial Presenilin Mutations and Sporadic Alzheimer's Disease Pathology: Is the Assumption of Biochemical Equivalence Justified?Proteomic analysis of leptomeningeal amyloid fibril extracts of cerebral amyloid angiopathy (CAA) patients with or without corticosteroid therapy.Secretion of long Abeta-related peptides processed at epsilon-cleavage site is dependent on the alpha-secretase pre-cutting.Abeta43 is more frequent than Abeta40 in amyloid plaque cores from Alzheimer disease brains.Biophysical characterization of longer forms of amyloid beta peptides: possible contribution to flocculent plaque formation.
P2860
Q33207923-6B91D084-8C17-44D0-9BA3-018DBBBE822BQ33801986-B294EB59-47AF-43C7-9D72-4BFD2530301CQ36121377-E904EF30-10F9-4782-890A-9B0301B4EABAQ36481949-6803BC9F-B792-4576-A470-D74C0823E548Q37247201-98CCBA8E-DE35-4EAD-AA07-1C7199E4A8B1Q37319340-5543F528-1673-4683-B109-0D080D720E22Q37342565-F0928F74-547D-42C2-A4A7-A6D3A75B95A0Q38693441-BFA9DCAC-9B63-44A9-8A74-AD0C28159C1CQ44259961-FD62EC55-BC7C-4B3E-9017-30AD5F6AC5CCQ44976555-BE3763BF-1BFF-4EA4-82CB-F417FEAED15CQ46003834-63C78531-4C8C-4A38-896F-F8AF47ED0D6DQ46814171-97186841-924D-41DB-AE76-99F007467F66
P2860
The human amyloid-beta precursor protein770 mutation V717F generates peptides longer than amyloid-beta-(40-42) and flocculent amyloid aggregates.
description
2003 nî lūn-bûn
@nan
2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
The human amyloid-beta precurs ...... flocculent amyloid aggregates.
@ast
The human amyloid-beta precurs ...... flocculent amyloid aggregates.
@en
type
label
The human amyloid-beta precurs ...... flocculent amyloid aggregates.
@ast
The human amyloid-beta precurs ...... flocculent amyloid aggregates.
@en
prefLabel
The human amyloid-beta precurs ...... flocculent amyloid aggregates.
@ast
The human amyloid-beta precurs ...... flocculent amyloid aggregates.
@en
P2093
P2860
P356
P1476
The human amyloid-beta precurs ...... flocculent amyloid aggregates
@en
P2093
Alex E Roher
Bernardino Ghetti
Daniel Brune
Dean C Luehrs
Jennifer Childress
Jill Murrell
John Lopez
Martin Farlow
Nicole Weiss
P2860
P304
P356
10.1074/JBC.M311380200
P407
P50
P577
2003-11-26T00:00:00Z