Identification of a novel class of farnesylation targets by structure-based modeling of binding specificity.
about
Towards the systematic mapping and engineering of the protein prenylation machinery in Saccharomyces cerevisiaeComputational protein design quantifies structural constraints on amino acid covariationExpansion of protein farnesyltransferase specificity using "tunable" active site interactions: development of bioengineered prenylation pathways.Protein prenylation: enzymes, therapeutics, and biotechnology applications.Computational design of selective peptides to discriminate between similar PDZ domains in an oncogenic pathwayPredicting peptide-mediated interactions on a genome-wide scale.In Silico Generation of Peptides by Replica Exchange Monte Carlo: Docking-Based Optimization of Maltose-Binding-Protein Ligands.Analogs of farnesyl diphosphate alter CaaX substrate specificity and reactions rates of protein farnesyltransferaseEnriching Peptide Libraries for Binding Affinity and Specificity Through Computationally Directed Library Design.Bacterial toxin effector-membrane targeting: outside in, then back again.Recent advances in protein prenyltransferases: substrate identification, regulation, and disease interventions.Escherichia coli Quorum-Sensing EDF, A Peptide Generated by Novel Multiple Distinct Mechanisms and Regulated by trans-Translation.Protein lipid modifications--More than just a greasy ballast.Type II Secretion Substrates of Legionella pneumophila Translocate Out of the Pathogen-Occupied Vacuole via a Semipermeable Membrane.MFPred: Rapid and accurate prediction of protein-peptide recognition multispecificity using self-consistent mean field theory.Structure-Based Identification of HDAC8 Non-histone SubstratesIn silico and in vitro elucidation of BH3 binding specificity toward Bcl-2Protein Lipidation: Occurrence, Mechanisms, Biological Functions, and Enabling Technologies.Efficient farnesylation of an extended C-terminal C(x)3X sequence motif expands the scope of the prenylated proteome.FlexPepDock lessons from CAPRI peptide-protein rounds and suggested new criteria for assessment of model quality and utility.180 Towards the high-resolution, ab initio modeling of peptide-mediated interactions.Isoprenoids and protein prenylation: implications in the pathogenesis and therapeutic intervention of Alzheimer's disease.
P2860
Q28544006-17120CFA-AA2B-4F6A-9D38-FF41E2A07196Q28914725-CED400FC-F17F-45ED-A381-6877B5ED70C0Q30421452-5FBEC9AD-1E12-4203-835A-A1338187ADC8Q34992469-5B5BAB2E-3774-43CE-AD66-61BA1E54E9C3Q35468530-DEF2D571-B8DD-4708-9824-13987BF5617BQ35621798-772657EC-E0B4-46D0-938B-3E301BBA206AQ35739794-D76C7BA6-2EF9-443F-9E97-C4672116F07DQ35902395-EAC2B993-AA81-45F1-BF69-2732A437B9CBQ36290587-D16555E7-AA40-4651-80C3-C06664F82C18Q38037558-DA6DDBCD-4B93-4838-A7FA-08DCE5A33B59Q38058956-100C9726-3C3F-4618-B42A-9DA063D62038Q38265321-8E45B555-450D-449E-AE5C-50ED8350438AQ38673481-1DC2395E-9454-4EA6-B951-48FC49B43F4DQ40164466-96BE6013-39B1-4A51-A55E-1CDEC71B8DB0Q40995571-CB9DF99F-B921-4355-A1F0-F890B75F9CA7Q41496911-27AF07AF-B090-402F-AFD2-7280B4EFCA02Q41958792-24BAA9D0-24BC-4067-8302-808F90831D79Q47239374-D25FECF3-C5B0-4A17-82E5-A260E45F7714Q47251070-0BDCA5C2-2F09-4EBD-9786-F4E329569228Q47566942-71EE08DC-C3A2-45F6-9820-0DBC659B6C59Q47570026-5E1760AA-A22D-4F01-8F3E-CC8CF9412558Q54223105-50C65DCC-29CA-49A6-95B8-A7601C1572AB
P2860
Identification of a novel class of farnesylation targets by structure-based modeling of binding specificity.
description
2011 nî lūn-bûn
@nan
2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Identification of a novel clas ...... deling of binding specificity.
@ast
Identification of a novel clas ...... deling of binding specificity.
@en
type
label
Identification of a novel clas ...... deling of binding specificity.
@ast
Identification of a novel clas ...... deling of binding specificity.
@en
prefLabel
Identification of a novel clas ...... deling of binding specificity.
@ast
Identification of a novel clas ...... deling of binding specificity.
@en
P2860
P50
P1476
Identification of a novel clas ...... deling of binding specificity.
@en
P2093
Carol A Fierke
Corissa L Lamphear
P2860
P304
P356
10.1371/JOURNAL.PCBI.1002170
P577
2011-10-06T00:00:00Z