The energy landscape analysis of cancer mutations in protein kinases
about
Simulating molecular mechanisms of the MDM2-mediated regulatory interactions: a conformational selection model of the MDM2 lid dynamicsProbing molecular mechanisms of the Hsp90 chaperone: biophysical modeling identifies key regulators of functional dynamics.A conserved isoleucine maintains the inactive state of Bruton's tyrosine kinaseOncogenic potential is related to activating effect of cancer single and double somatic mutations in receptor tyrosine kinasesAllosteric communication across the native and mutated KIT receptor tyrosine kinase.Frustration in biomoleculesProtein Frustratometer 2: a tool to localize energetic frustration in protein molecules, now with electrostaticsOncogenic Mutations Differentially Affect Bax Monomer, Dimer, and Oligomeric Pore Formation in the Membrane.Intrinsically semi-disordered state and its role in induced folding and protein aggregationStructure-functional prediction and analysis of cancer mutation effects in protein kinases.Distributions of experimental protein structures on coarse-grained free energy landscapes.Analysis of somatic mutations across the kinome reveals loss-of-function mutations in multiple cancer types.
P2860
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P2860
The energy landscape analysis of cancer mutations in protein kinases
description
2011 nî lūn-bûn
@nan
2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年學術文章
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name
The energy landscape analysis of cancer mutations in protein kinases
@ast
The energy landscape analysis of cancer mutations in protein kinases
@en
type
label
The energy landscape analysis of cancer mutations in protein kinases
@ast
The energy landscape analysis of cancer mutations in protein kinases
@en
prefLabel
The energy landscape analysis of cancer mutations in protein kinases
@ast
The energy landscape analysis of cancer mutations in protein kinases
@en
P2860
P1433
P1476
The energy landscape analysis of cancer mutations in protein kinases
@en
P2093
Anshuman Dixit
P2860
P304
P356
10.1371/JOURNAL.PONE.0026071
P407
P577
2011-10-06T00:00:00Z