Low molecular weight peptides restore the procoagulant activity of factor VIII in the presence of the potent inhibitor antibody ESH8.
about
Covalent inactivation of factor VIII antibodies from hemophilia A patients by an electrophilic FVIII Analog.A consensus tetrapeptide selected by phage display adopts the conformation of a dominant discontinuous epitope of a monoclonal anti-VWF antibody that inhibits the von Willebrand factor-collagen interaction.Platelet-delivered factor VIII provides limited resistance to anti-factor VIII inhibitors.Haemophilia A: from mutation analysis to new therapies.Induction of tolerance to factor VIII inhibitors by gene therapy with immunodominant A2 and C2 domains presented by B cells as Ig fusion proteins.Discontinuous epitopes on the C2 domain of coagulation Factor VIII mapped by computer-designed synthetic peptides.Characterisation of the epitope for a herpes simplex virus glycoprotein B-specific monoclonal antibody with high protective capacity.Reactivity profile of anti-factor VIII antibodies with designed synthetic peptides mimicking epitopes of the C2 and a1 domains.Kinetic parameters of monoclonal antibodies ESH2, ESH4, ESH5, and ESH8 on coagulation factor VIII and their influence on factor VIII activity.
P2860
Q30481770-D0404813-1052-43DF-BE6C-52F1F585DF7CQ30961540-D270461A-DC8F-4340-A53B-F39978664AFBQ33379383-A0C65240-28F6-4592-BAF3-D5A9976A47C9Q36148386-046E5F7F-2EF7-4F97-89B9-29F18C7E37CDQ40446327-92C94BF7-E9C8-407D-9300-CB6855AAFC00Q44140043-9229A991-7EA0-41BA-8646-675C3E4B718BQ45372480-AABA6BD8-9CE2-40DA-AF82-F90A661BD4E0Q45876892-016A8790-90AB-4B67-ADFA-7F2CB47344E4Q51780657-C652A5F7-26B8-4ADD-8B9D-342D1C969821
P2860
Low molecular weight peptides restore the procoagulant activity of factor VIII in the presence of the potent inhibitor antibody ESH8.
description
2002 nî lūn-bûn
@nan
2002 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Low molecular weight peptides ...... otent inhibitor antibody ESH8.
@ast
Low molecular weight peptides ...... otent inhibitor antibody ESH8.
@en
type
label
Low molecular weight peptides ...... otent inhibitor antibody ESH8.
@ast
Low molecular weight peptides ...... otent inhibitor antibody ESH8.
@en
prefLabel
Low molecular weight peptides ...... otent inhibitor antibody ESH8.
@ast
Low molecular weight peptides ...... otent inhibitor antibody ESH8.
@en
P2093
P2860
P356
P1476
Low molecular weight peptides ...... otent inhibitor antibody ESH8.
@en
P2093
Claude Granier
Dominique Piquer
Jean-Marie Saint-Remy
Jean-Paul Léonetti
Sanjee Raut
Sylvie Villard
P2860
P304
27232-27239
P356
10.1074/JBC.M203415200
P407
P577
2002-05-14T00:00:00Z