Combinatorial chemistry: libraries from libraries, the art of the diversity-oriented transformation of resin-bound peptides and chiral polyamides to low molecular weight acyclic and heterocyclic compounds.

Combinatorial chemistry: libraries from libraries, the art of the diversity-oriented transformation of resin-bound peptides and chiral polyamides to low molecular weight acyclic and heterocyclic compounds.

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http://www.wikidata.org/entity/Q31063489

Q31063489

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Towards the optimal screening collection: a synthesis strategy SIRT1 top 40 hits: use of one-bead, one-compound acetyl-peptide libraries and quantum dots to probe deacetylase specificity.Fluorous mixture synthesis of two libraries with hydantoin-, and benzodiazepinedione-fused heterocyclic scaffolds.Chemically engineered extracts as an alternative source of bioactive natural product-like compounds.Identification, structure-activity relationships and molecular modeling of potent triamine and piperazine opioid ligands.Identification of two novel, potent, low-liability antinociceptive compounds from the direct in vivo screening of a large mixture-based combinatorial library A peptide & peptide nucleic acid synthesis technology for transporter molecules and theranostics--the SPPS.Increased diversity of libraries from libraries: chemoinformatic analysis of bis-diazacyclic libraries.Inhibitor screening of proprotein convertases using positional scanning libraries.A novel method for the determination of isokinetic ratios and its application in the synthesis of two new positional scanning libraries Synthesis of rhenium-centric reverse turn mimics.Selective agonists and antagonists of formylpeptide receptors: duplex flow cytometry and mixture-based positional scanning libraries.Balancing novelty with confined chemical space in modern drug discovery.Libraries from Libraries: A Series of Sulfonamide Linked Heterocycles Derived from the Same Scaffold.High-Throughput Screening by Nuclear Magnetic Resonance (HTS by NMR) for the Identification of PPIs Antagonists Carbohydrates in diversity-oriented synthesis: challenges and opportunities.Direct Phenotypic Screening in Mice: Identification of Individual, Novel Antinociceptive Compounds from a Library of 734,821 Pyrrolidine Bis-piperazines.Scaffold ranking and positional scanning utilized in the discovery of nAChR-selective compounds suitable for optimization studies.Parallel Synthesis of Structurally Diverse Aminobenzimidazole Tethered Sultams and Benzothiazepinones.Solid Phase Synthesis of Isoxazole and Isoxazoline-carboxamides via [2+3]-Dipolar Cycloaddition Using Resin-bound Alkynes or Alkenes.Synthesis and application of isocyanates radiolabeled with carbon-11.

P2860

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P2860

Combinatorial chemistry: libraries from libraries, the art of the diversity-oriented transformation of resin-bound peptides and chiral polyamides to low molecular weight acyclic and heterocyclic compounds.

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http://www.wikidata.org/entity/Q31063489

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2004 nî lūn-bûn

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2004 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2004 թվականի մայիսին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年論文

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2004年论文

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