Electrophilic chemistry related to skin sensitization. Reaction mechanistic applicability domain classification for a published data set of 106 chemicals tested in the mouse local lymph node assay.
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Pyridoxylamine reactivity kinetics as an amine based nucleophile for screening electrophilic dermal sensitizersReactivity measurement in estimation of benzoquinone and benzoquinone derivatives' allergenicityPredicting chemically-induced skin reactions. Part I: QSAR models of skin sensitization and their application to identify potentially hazardous compoundsMethyl methacrylate and respiratory sensitization: a critical reviewIntegrated Computational Solution for Predicting Skin Sensitization Potential of MoleculesMixture toxicity of SN2-reactive soft electrophiles: 1. Evaluation of mixtures containing α-halogenated acetonitriles.Non-animal sensitization testing: state-of-the-art.A review of the electrophilic reaction chemistry involved in covalent protein binding relevant to toxicity.New concepts in cutaneous allergy.Antioxidant sulforaphane and sensitizer trinitrobenzene sulfonate induce carboxylesterase-1 through a novel element transactivated by nuclear factor-E2 related factor-2.An in vitro method for detecting chemical sensitization using human reconstructed skin models and its applicability to cosmetic, pharmaceutical, and medical device safety testing.Is skin penetration a determining factor in skin sensitization potential and potency? Refuting the notion of a LogKow threshold for skin sensitization.What determines skin sensitization potency: Myths, maybes and realities. The 500 molecular weight cut-off: An updated analysis.Integrated testing and assessment approaches for skin sensitization: a commentary.What determines skin sensitization potency-myths, maybes and realities. Part 1. The 500 molecular weight cut-off.Can mutagenicity information be useful in an Integrated Testing Strategy (ITS) for skin sensitization?Occupational contact allergy caused by rubber gloves--nothing has changed.Fragment-based prediction of skin sensitization using recursive partitioning.Determination of Protein Haptenation by Chemical Sensitisers within the Complexity of the Human Skin Proteome.Application of IATA - A case study in evaluating the global and local performance of a Bayesian network model for skin sensitization.TIMES-SS--recent refinements resulting from an industrial skin sensitisation consortium.Stable isotope labeling method for the investigation of protein haptenation by electrophilic skin sensitizers.Toxicity of organic pollutants to seven aquatic organisms: effect of polarity and ionization.Identification of mechanisms of toxic action for skin sensitisation using a SMARTS pattern based approach.An evaluation of selected (Q)SARs/expert systems for predicting skin sensitisation potential.
P2860
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P2860
Electrophilic chemistry related to skin sensitization. Reaction mechanistic applicability domain classification for a published data set of 106 chemicals tested in the mouse local lymph node assay.
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Electrophilic chemistry relate ...... mouse local lymph node assay.
@ast
Electrophilic chemistry relate ...... mouse local lymph node assay.
@en
type
label
Electrophilic chemistry relate ...... mouse local lymph node assay.
@ast
Electrophilic chemistry relate ...... mouse local lymph node assay.
@en
prefLabel
Electrophilic chemistry relate ...... mouse local lymph node assay.
@ast
Electrophilic chemistry relate ...... mouse local lymph node assay.
@en
P356
P1476
Electrophilic chemistry relate ...... mouse local lymph node assay.
@en
P2093
Aynur O Aptula
David W Roberts
P356
10.1021/TX060121Y
P577
2007-01-01T00:00:00Z