A method to integrate benchmark dose estimates with genomic data to assess the functional effects of chemical exposure.
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System-based identification of toxicity pathways associated with multi-walled carbon nanotube-induced pathological responsesNew perspectives for in vitro risk assessment of multiwalled carbon nanotubes: application of coculture and bioinformaticsSystems biology and biomarkers of early effects for occupational exposure limit settingAdaptive Posttranslational Control in Cellular Stress Response Pathways and Its Relationship to Toxicity Testing and Safety AssessmentComparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in drinking waterEffect of chemical mutagens and carcinogens on gene expression profiles in human TK6 cellsAssessment of the mode of action underlying development of rodent small intestinal tumors following oral exposure to hexavalent chromium and relevance to humansDeveloping tools for defining and establishing pathways of toxicityIncorporating new technologies into toxicity testing and risk assessment: moving from 21st century vision to a data-driven framework.BMDExpress: a software tool for the benchmark dose analyses of genomic data.Recommended approaches in the application of toxicogenomics to derive points of departure for chemical risk assessment.The vanishing zero revisited: thresholds in the age of genomics.Comparison of microarrays and RNA-seq for gene expression analyses of dose-response experiments.Differential reconstructed gene interaction networks for deriving toxicity threshold in chemical risk assessmentIdentification of Stage-Specific Gene Expression Signatures in Response to Retinoic Acid during the Neural Differentiation of Mouse Embryonic Stem Cells.The plasma proteome, adductome and idiosyncratic toxicity in toxicoproteomics researchOpportunities for an alternative integrating testing strategy for carcinogen hazard assessment?Integrating toxicogenomics into human health risk assessment: lessons learned from the benzo[a]pyrene case study.Editor's Highlight: Dose-Response Analysis of RNA-Seq Profiles in Archival Formalin-Fixed Paraffin-Embedded Samples.Editor's Highlight: Application of Gene Set Enrichment Analysis for Identification of Chemically Induced, Biologically Relevant Transcriptomic Networks and Potential Utilization in Human Health Risk Assessment.High-throughput concentration-response analysis for omics datasets.Evaluation of gene expression changes in human primary lung epithelial cells following 24-hr exposures to inorganic arsenic and its methylated metabolites and to arsenic trioxide.Computational toxicology: realizing the promise of the toxicity testing in the 21st century.Dose-response modeling of early molecular and cellular key events in the CAR-mediated hepatocarcinogenesis pathway.Cross-species transcriptomic analysis of mouse and rat lung exposed to chloroprene.Development and evaluation of a genomic signature for the prediction and mechanistic assessment of nongenotoxic hepatocarcinogens in the rat.The good, the bad, and the toxic: approaching hormesis in Daphnia magna exposed to an energetic compound.Formaldehyde: integrating dosimetry, cytotoxicity, and genomics to understand dose-dependent transitions for an endogenous compound.Editor's Highlight: Comparative Dose-Response Analysis of Liver and Kidney Transcriptomic Effects of Trichloroethylene and Tetrachloroethylene in B6C3F1 Mouse.Modern methodologies and tools for human hazard assessment of chemicalsBenchmark dose analyses of multiple genetic toxicity endpoints permit robust, cross-tissue comparisons of MutaMouse responses to orally delivered benzo[a]pyrene.Population-based dose-response analysis of liver transcriptional response to trichloroethylene in mouse.Genetic variation and risk of DNA damage in peripheral blood lymphocytes of Iranian formaldehyde-exposed workers.Concentration- and time-dependent genomic changes in the mouse urinary bladder following exposure to arsenate in drinking water for up to 12 weeks.Genotoxicity in vinyl chloride-exposed workers and its implication for occupational exposure limit.Development of occupational exposure limits for the Hanford tank farms.Toxicogenomics for transcription factor-governed molecular pathways: moving on to roles beyond classification and predictionAnalysis of Transcriptomic Dose-Response Data for Toxicology and Risk AssessmentSoy supplementation: Impact on gene expression in different tissues of ovariectomized rats and evaluation of the rat model to predict (post)menopausal health effect
P2860
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P2860
A method to integrate benchmark dose estimates with genomic data to assess the functional effects of chemical exposure.
description
2007 nî lūn-bûn
@nan
2007 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
A method to integrate benchmar ...... effects of chemical exposure.
@ast
A method to integrate benchmar ...... effects of chemical exposure.
@en
type
label
A method to integrate benchmar ...... effects of chemical exposure.
@ast
A method to integrate benchmar ...... effects of chemical exposure.
@en
prefLabel
A method to integrate benchmar ...... effects of chemical exposure.
@ast
A method to integrate benchmar ...... effects of chemical exposure.
@en
P2093
P356
P1476
A method to integrate benchmar ...... effects of chemical exposure.
@en
P2093
Bruce C Allen
Edilberto Bermudez
Harvey J Clewell
Longlong Yang
P304
P356
10.1093/TOXSCI/KFM092
P577
2007-04-21T00:00:00Z