Causal and synthetic associations of variants in the SERPINA gene cluster with alpha1-antitrypsin serum levels.
about
Fifty years on: GWAS confirms the role of a rare variant in lung disease.Common coding variant in SERPINA1 increases the risk for large artery stroke.Attenuating immune pathology using a microbial-based intervention in a mouse model of cigarette smoke-induced lung inflammation.Gene susceptibility identification in a longitudinal study confirms new loci in the development of chronic obstructive pulmonary disease and influences lung function decline.Increased Transcript Complexity in Genes Associated with Chronic Obstructive Pulmonary DiseaseThree missense variants of metabolic syndrome-related genes are associated with alpha-1 antitrypsin levelsInformed genome-wide association analysis with family history as a secondary phenotype identifies novel loci of lung cancer.Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD.Exome-wide analysis of rare coding variation identifies novel associations with COPD and airflow limitation in MOCS3, IFIT3 and SERPINA12.Cistrome-based Cooperation between Airway Epithelial Glucocorticoid Receptor and NF-κB Orchestrates Anti-inflammatory EffectsMolecular mechanisms underlying variations in lung function: a systems genetics analysis.Interactions between single nucleotide polymorphism of SERPINA1 gene and smoking in association with COPD: a case-control study.Trans-ethnic follow-up of breast cancer GWAS hits using the preferential linkage disequilibrium approach.Genetic Association and Risk Scores in a Chronic Obstructive Pulmonary Disease Meta-analysis of 16,707 Subjects.Partial IGF-1 deficiency is sufficient to reduce heart contractibility, angiotensin II sensibility, and alter gene expression of structural and functional cardiac proteins.SEGtool: a specifically expressed gene detection tool and applications in human tissue and single-cell sequencing data.Analysis of genomic copy number variation in equine recurrent airway obstruction (heaves).α1-Antitrypsin deficiency.Genetic regulation of gene expression in the lung identifies CST3 and CD22 as potential causal genes for airflow obstruction.SERPINA1 methylation and lung function in tobacco-smoke exposed European children and adults: a meta-analysis of ALEC population-based cohortsGenome-wide association study of lung function and clinical implication in heavy smokers
P2860
Q31130026-E8E7DF7A-58C9-44FC-8106-FFE2DA408625Q33556760-123E0424-457B-4CBA-B88B-8845A43D4D29Q33692100-2A213827-7CCD-4B32-B71A-7C3C8EB1AF44Q35595026-68F2953A-DF68-4369-81F7-33D3184CE68CQ35812803-0727D15E-5091-4692-AA30-EBD5F4F6BDCDQ35898478-435510A0-8DDB-4291-93CF-5D7CB603489DQ36011058-ED892577-19DB-46DA-8766-D7AF77EF5F61Q36105702-2E1E494E-D4E8-4536-A37C-47A1A79DBE1AQ36968835-0E65EE85-4AB6-4DFC-9BA5-A39CDA54A10DQ37066464-2DD6A3A5-C80D-4BD9-806C-03934BED90DAQ37252370-781C1EB6-5E1D-4ADC-926E-03D227A9C974Q37588117-4AD85ADC-1526-45B0-BEC0-F0EA6E846154Q37686157-9B8D8C0B-3839-425F-8A8B-87110F6ADEEAQ38974166-9A30B1ED-039F-431E-B88D-822396009A51Q41383801-CC60AC2D-E791-4F4E-84D7-73D1F72D84D0Q42778005-F443A815-9D27-4F19-A120-2C768A2BDAF6Q47881812-3A861FD7-B55F-4288-B800-544403A1985FQ51481224-29CA9D1C-2E62-4DD5-B0A3-0B5CBA110DB9Q51700279-26E080AB-72FB-4A89-9C3F-83F5758D1F5CQ57416629-ED300CB3-1095-4608-B98E-1BE61A168808Q58805933-B4442535-B000-4DB2-8629-A603542C2480
P2860
Causal and synthetic associations of variants in the SERPINA gene cluster with alpha1-antitrypsin serum levels.
description
2013 nî lūn-bûn
@nan
2013 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
name
Causal and synthetic associati ...... pha1-antitrypsin serum levels.
@ast
Causal and synthetic associati ...... pha1-antitrypsin serum levels.
@en
type
label
Causal and synthetic associati ...... pha1-antitrypsin serum levels.
@ast
Causal and synthetic associati ...... pha1-antitrypsin serum levels.
@en
prefLabel
Causal and synthetic associati ...... pha1-antitrypsin serum levels.
@ast
Causal and synthetic associati ...... pha1-antitrypsin serum levels.
@en
P2093
P2860
P50
P1433
P1476
Causal and synthetic associati ...... pha1-antitrypsin serum levels.
@en
P2093
Alan L James
Andrew J Sandford
Beate Koch
David P Strachan
Erich W Russi
Eva Albrecht
Florian Kronenberg
Holger Schulz
Ilaria Ferrarotti
Ivan Curjuric
P2860
P304
P356
10.1371/JOURNAL.PGEN.1003585
P50
P577
2013-08-22T00:00:00Z