Animal data: the contributions of the Ussing Chamber and perfusion systems to predicting human oral drug delivery in vivo.
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Predicting Drug Extraction in the Human Gut Wall: Assessing Contributions from Drug Metabolizing Enzymes and Transporter Proteins using Preclinical ModelsTranslating Human Effective Jejunal Intestinal Permeability to Surface-Dependent Intrinsic Permeability: a Pragmatic Method for a More Mechanistic Prediction of Regional Oral Drug Absorption.Self-microemulsifying drug delivery system for improving the bioavailability of huperzine A by lymphatic uptake.Evidence of D-phenylglycine as delivering tool for improving L-dopa absorptionSignificance of peptide transporter 1 in the intestinal permeability of valacyclovir in wild-type and PepT1 knockout mice.Relevance of PepT1 in the intestinal permeability and oral absorption of cefadroxilSubacute oral toxicity study of ethanolic leaves extracts of Strobilanthes crispus in rats.Species differences in the pharmacokinetics of cefadroxil as determined in wildtype and humanized PepT1 micePermeation of four oral drugs through human intestinal mucosaMitigating permeability-mediated risks in drug discovery.Utility of models of the gastrointestinal tract for assessment of the digestion and absorption of engineered nanomaterials released from food matrices.In vitro oral drug permeation models: the importance of taking physiological and physico-chemical factors into consideration.Lipid-associated oral delivery: Mechanisms and analysis of oral absorption enhancement.Semisynthesis, cytotoxic activity, and oral availability of new lipophilic 9-substituted camptothecin derivatives.Frog intestinal perfusion to evaluate drug permeability: application to p-gp and cyp3a4 substrates.The fraction dose absorbed, in humans, and high jejunal human permeability relationship.Mathematical modeling of oral absorption and bioavailability of a fluoroquinolone after its precipitation in the gastrointestinal tract.The effect of P-glycoprotein on methadone hydrochloride flux in equine intestinal mucosa.Solid dispersion tablets of breviscapine with polyvinylpyrrolidone K30 for improved dissolution and bioavailability to commercial breviscapine tablets in beagle dogs.An improved prediction of the human in vivo intestinal permeability and BCS class of drugs using the in vitro permeability ratio obtained for rat intestine using an Ussing chamber system.Closed-Loop Doluisio (Colon, Small Intestine) and Single-Pass Intestinal Perfusion (Colon, Jejunum) in Rat-Biophysical Model and Predictions Based on Caco-2.Particle size reduction and pharmacokinetic evaluation of a poorly soluble acid and a poorly soluble base during early development.
P2860
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P2860
Animal data: the contributions of the Ussing Chamber and perfusion systems to predicting human oral drug delivery in vivo.
description
2007 nî lūn-bûn
@nan
2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Animal data: the contributions ...... an oral drug delivery in vivo.
@ast
Animal data: the contributions ...... an oral drug delivery in vivo.
@en
type
label
Animal data: the contributions ...... an oral drug delivery in vivo.
@ast
Animal data: the contributions ...... an oral drug delivery in vivo.
@en
prefLabel
Animal data: the contributions ...... an oral drug delivery in vivo.
@ast
Animal data: the contributions ...... an oral drug delivery in vivo.
@en
P1476
Animal data: the contributions ...... an oral drug delivery in vivo.
@en
P2093
Hans Lennernäs
P304
P356
10.1016/J.ADDR.2007.06.016
P407
P577
2007-08-22T00:00:00Z