Specific locations of hydrophilic amino acids in constructed transmembrane ligands of the platelet-derived growth factor beta receptor.
about
Packing contacts can mediate highly specific interactions between artificial transmembrane proteins and the PDGFbeta receptor.Artificial transmembrane oncoproteins smaller than the bovine papillomavirus E5 protein redefine sequence requirements for activation of the platelet-derived growth factor beta receptor.Construction and genetic selection of small transmembrane proteins that activate the human erythropoietin receptor.Construction and maintenance of randomized retroviral expression libraries for transmembrane protein engineering.The E5 proteinsViral miniproteinsMapping the homodimer interface of an optimized, artificial, transmembrane protein activator of the human erythropoietin receptor.Modulation of cell function by small transmembrane proteins modeled on the bovine papillomavirus E5 protein.A single amino acid substitution converts a transmembrane protein activator of the platelet-derived growth factor β receptor into an inhibitor.Protein-protein interactions in the membrane: sequence, structural, and biological motifs.The bovine papillomavirus E5 protein and the PDGF beta receptor: it takes two to tango.De novo selection of oncogenes.Interaction and conformational dynamics of membrane-spanning protein helices.Compensatory mutants of the bovine papillomavirus E5 protein and the platelet-derived growth factor β receptor reveal a complex direct transmembrane interaction.Single methyl groups can act as toggle switches to specify transmembrane Protein-protein interactions.
P2860
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P2860
Specific locations of hydrophilic amino acids in constructed transmembrane ligands of the platelet-derived growth factor beta receptor.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Specific locations of hydrophi ...... d growth factor beta receptor.
@ast
Specific locations of hydrophi ...... d growth factor beta receptor.
@en
type
label
Specific locations of hydrophi ...... d growth factor beta receptor.
@ast
Specific locations of hydrophi ...... d growth factor beta receptor.
@en
prefLabel
Specific locations of hydrophi ...... d growth factor beta receptor.
@ast
Specific locations of hydrophi ...... d growth factor beta receptor.
@en
P2093
P1476
Specific locations of hydrophi ...... d growth factor beta receptor.
@en
P2093
Anne P B Edwards
Daniel Dimaio
Donald M Engelman
Kristin E Yates
Lisa L Freeman-Cook
P304
P356
10.1016/J.JMB.2004.10.072
P407
P50
P577
2005-01-01T00:00:00Z