Direct in vitro selection of a 2'-O-methyl aptamer to VEGF. - Wikidata - awgldk - TriplyDB

Direct in vitro selection of a 2'-O-methyl aptamer to VEGF.

Direct in vitro selection of a 2'-O-methyl aptamer to VEGF.

http://www.wikidata.org/entity/Q31142871

about

Modified Nucleoside Triphosphates for In-vitro Selection Techniques From selection hits to clinical leads: progress in aptamer discovery Progress and Challenges in Developing Aptamer-Functionalized Targeted Drug Delivery Systems Generation of Aptamers with an Expanded Chemical Repertoire In vitro selection using modified or unnatural nucleotides Aptamers in diagnostics and treatment of viral infections Smart functional nucleic acid chimeras: enabling tissue specific RNA targeting therapy Structural basis for specific inhibition of Autotaxin by a DNA aptamer Therapeutic aptamers: developmental potential as anticancer drugs Aptamer-Drug Conjugates Multitasking by multivalent circular DNA aptamers.Simultaneous targeting of CD44 and EpCAM with a bispecific aptamer effectively inhibits intraperitoneal ovarian cancer growth.Bioimaging of nucleolin aptamer-containing 5-(N-benzylcarboxyamide)-2'-deoxyuridine more capable of specific binding to targets in cancer cells Strategies for the discovery of therapeutic aptamers.Selection of Nucleic Acid Aptamers Targeting Tumor Cell-Surface Protein Biomarkers Targeting 4-1BB costimulation to the tumor stroma with bispecific aptamer conjugates enhances the therapeutic index of tumor immunotherapy.Recent developments in protein and cell-targeted aptamer selection and applications Synthetic genetic polymers capable of heredity and evolution.Molecular diagnostic and drug delivery agents based on aptamer-nanomaterial conjugates.Highly parallel translation of DNA sequences into small molecules.A therapeutic aptamer inhibits angiogenesis by specifically targeting the heparin binding domain of VEGF165 Artificial specific binders directly recovered from chemically modified nucleic acid libraries.Investigating the antiproliferative activity of high affinity DNA aptamer on cancer cells Sequential injection analysis for optimization of molecular biology reactions.Highly stable aptamers selected from a 2'-fully modified fGmH RNA library for targeting biomaterials.Tracking the emergence of high affinity aptamers for rhVEGF165 during capillary electrophoresis-systematic evolution of ligands by exponential enrichment using high throughput sequencing.RAPID-SELEX for RNA aptamers Nucleic Acid Ligands With Protein-like Side Chains: Modified Aptamers and Their Use as Diagnostic and Therapeutic Agents Rational truncation of an RNA aptamer to prostate-specific membrane antigen using computational structural modeling.Aptamers as a novel tool for diagnostics and therapy.A survey of advancements in nucleic acid-based logic gates and computing for applications in biotechnology and biomedicine.Aptamer technology for tracking cells' status & function.Transcription yield of fully 2'-modified RNA can be increased by the addition of thermostabilizing mutations to T7 RNA polymerase mutants.In vitro evolution of chemically-modified nucleic acid aptamers: Pros and cons, and comprehensive selection strategies Single-step nanoplasmonic VEGF165 aptasensor for early cancer diagnosis.Engineering of targeted nanoparticles for cancer therapy using internalizing aptamers isolated by cell-uptake selection.Nanoparticle-aptamer bioconjugates for cancer targeting.Gene therapy progress and prospects: RNA aptamers.Assembling OX40 aptamers on a molecular scaffold to create a receptor-activating aptamer.Strategies for enhanced photodynamic therapy effects.

P2860

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P2860

Direct in vitro selection of a 2'-O-methyl aptamer to VEGF.

http://www.wikidata.org/entity/Q31142871

description

2005 nî lūn-bûn

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2005 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2005 թվականի հունվարին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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Direct in vitro selection of a 2'-O-methyl aptamer to VEGF.

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Direct in vitro selection of a 2'-O-methyl aptamer to VEGF.

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Direct in vitro selection of a 2'-O-methyl aptamer to VEGF.

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Direct in vitro selection of a 2'-O-methyl aptamer to VEGF.

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Direct in vitro selection of a 2'-O-methyl aptamer to VEGF.

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Direct in vitro selection of a 2'-O-methyl aptamer to VEGF.

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J.CHEMBIOL.2004.10.017

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Chemistry and Biology

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Direct in vitro selection of a 2'-O-methyl aptamer to VEGF.

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Anthony D Keefe

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Charles Wilson

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David M Epstein

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Jeffrey C Kurz

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Jeffrey R Preiss

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Lillian R Horwitz

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P Shannon Pendergrast

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Paula E Burmeister

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Robert F Silva

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Scott D Lewis

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10.1016/J.CHEMBIOL.2004.10.017

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