Discovery and structure-activity relationship of quinuclidine benzamides as agonists of alpha7 nicotinic acetylcholine receptors. - Wikidata - awgldk - TriplyDB

Discovery and structure-activity relationship of quinuclidine benzamides as agonists of alpha7 nicotinic acetylcholine receptors.

Discovery and structure-activity relationship of quinuclidine benzamides as agonists of alpha7 nicotinic acetylcholine receptors.

http://www.wikidata.org/entity/Q31147815

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Discovery of novel alpha7 nicotinic receptor antagonists Activation of nicotinic cholinergic receptors prevents ventilator-induced lung injury in rats Creating an 7 Nicotinic Acetylcholine Recognition Domain from the Acetylcholine-binding Protein: CRYSTALLOGRAPHIC AND LIGAND SELECTIVITY ANALYSES Mossy fiber long-term potentiation deficits in BACE1 knock-outs can be rescued by activation of alpha7 nicotinic acetylcholine receptors Multiple pharmacophores for the selective activation of nicotinic alpha7-type acetylcholine receptors Selective α4β2 nicotinic acetylcholine receptor agonists target epigenetic mechanisms in cortical GABAergic neurons Exploring chemical space for drug discovery using the chemical universe database.The Concise Guide to PHARMACOLOGY 2013/14: ligand-gated ion channels.Discovery of potent positive allosteric modulators of the α3β2 nicotinic acetylcholine receptor by a chemical space walk in ChEMBL.Alpha7 nicotinic acetylcholine receptor: a link between inflammation and neurodegeneration.Chemical and genetic engineering of selective ion channel-ligand interactions The frequency-dependence of the nicotine-induced inhibition of dopamine is controlled by the α7 nicotinic receptor α7 Nicotinic Receptor Agonists: Potential Therapeutic Drugs for Treatment of Cognitive Impairments in Schizophrenia and Alzheimer's Disease.Evidence of BrdU-positive retinal neurons after application of an Alpha7 nicotinic acetylcholine receptor agonist.alpha7 nicotinic acetylcholine receptor agonist properties of tilorone and related tricyclic analogues.Preclinical characterization of A-582941: a novel alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties.An experimental study on (131)I-CHIBA-1001: a radioligand for α7 nicotinic acetylcholine receptors.Exploring α7-Nicotinic Receptor Ligand Diversity by Scaffold Enumeration from the Chemical Universe Database GDB Cancer 'survivor-care': I. the α7 nAChR as potential target for chemotherapy-related cognitive impairment.Retinal ganglion cell neuroprotection induced by activation of alpha7 nicotinic acetylcholine receptors.α7 Nicotinic Receptor Promotes the Neuroprotective Functions of Astrocytes against Oxaliplatin Neurotoxicity Acetylcholine regulation of synoviocyte cytokine expression by the alpha7 nicotinic receptor.Alpha7 nicotinic acetylcholine receptors modulate motivation to self-administer nicotine: implications for smoking and schizophrenia.Identification and in vitro pharmacological characterization of a novel and selective α7 nicotinic acetylcholine receptor agonist, Br-IQ17B.Effects of nicotinic acetylcholine receptor agonists on cognition in rhesus monkeys with a chronic cocaine self-administration history.Neuroprotection of rat retinal ganglion cells mediated through alpha7 nicotinic acetylcholine receptors.Activation of the α7 nicotinic ACh receptor induces anxiogenic effects in rats which is blocked by a 5-HT₁a receptor antagonist.Effects of an alpha7 nicotinic receptor agonist and stress on spatial memory in an animal model of Alzheimer's disease.Chronic nicotine exposure stimulates biliary growth and fibrosis in normal rats Presynaptic α7 nicotinic acetylcholine receptors enhance hippocampal mossy fiber glutamatergic transmission via PKA activation.A nicotinic acetylcholine receptor agonist prevents loss of retinal ganglion cells in a glaucoma model.Evidence for a prosurvival role of alpha-7 nicotinic acetylcholine receptor in alternatively (M2)-activated macrophages.Redistribution of adrenomedullary nicotinic acetylcholine receptor subunits and the effect on circulating epinephrine levels in a murine model of acute asthma.Alpha7 neuronal nicotinic receptors as a drug target in schizophrenia.Positive allosteric modulation of alpha-7 nicotinic receptors promotes cell death by inducing Ca(2+) release from the endoplasmic reticulum.Behavioural effects of PNU-282987 and stress in an animal model of Alzheimer's disease.Pharmacology of alpha7 nicotinic acetylcholine receptor mediated extracellular signal-regulated kinase signalling in PC12 cells.Calcium signalling mediated through α7 and non-α7 nAChR stimulation is differentially regulated in bovine chromaffin cells to induce catecholamine release.Activation of the alpha7 nAChR reduces acid-induced acute lung injury in mice and rats.Crystal structure of 2-pentyl-oxybenzamide.

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P2860

Discovery and structure-activity relationship of quinuclidine benzamides as agonists of alpha7 nicotinic acetylcholine receptors.

http://www.wikidata.org/entity/Q31147815

description

2005 nî lūn-bûn

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2005 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2005 թվականի փետրվարին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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Discovery and structure-activi ...... tinic acetylcholine receptors.

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Discovery and structure-activi ...... tinic acetylcholine receptors.

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Discovery and structure-activi ...... tinic acetylcholine receptors.

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Discovery and structure-activi ...... tinic acetylcholine receptors.

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Discovery and structure-activi ...... tinic acetylcholine receptors.

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Discovery and structure-activi ...... tinic acetylcholine receptors.

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Alice L Bodnar

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Bruce N Rogers

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Dac M Dinh

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Erik Wong

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Mihaly Hajos

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10.1021/JM049363Q

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15715459

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