Beta-hairpin peptidomimetics: design, structures and biological activities.
about
Synthetic Peptides as Protein MimicsThe Role of Medical Structural Genomics in Discovering New Drugs for Infectious DiseasesDiscovery of Leukotriene A4 Hydrolase Inhibitors Using Metabolomics Biased Fragment Crystallography †A Left-Handed Solution to Peptide Inhibition of the p53-MDM2 InteractionDevelopment of a Peptide that Selectively Activates Protein Phosphatase-1 in Living CellsTwo Distinct Binding Modes Define the Interaction of Brox with the C-Terminal Tails of CHMP5 and CHMP4BAn Ultrahigh Affinity d -Peptide Antagonist Of MDM2Constrained peptides with target-adapted cross-links as inhibitors of a pathogenic protein-protein interactionBispidine-amino acid conjugates act as a novel scaffold for the design of antivirals that block Japanese encephalitis virus replicationRational Structure-Based Rescaffolding Approach to De Novo Design of Interleukin 10 (IL-10) Receptor-1 MimeticsMax Bergmann lecture protein epitope mimetics in the age of structural vaccinologyConstraining cyclic peptides to mimic protein structure motifs.N-acylpolyamine inhibitors of HDM2 and HDMX binding to p53.Differences in the transactivation domains of p53 family members: a computational study.Giant macrolactams based on β-sheet peptides.Anatomy of β-strands at protein-protein interfaces.A biomimetic polyketide-inspired approach to small-molecule ligand discovery.Control of proton and electron transfer in de novo designed, biomimetic β hairpins.Proline-glutamate chimera's side chain conformation directs the type of β-hairpin structure.A Cyclic Peptide Mimic of the β-Amyloid Binding Domain on Transthyretin.Discovery of a β-Hairpin Octapeptide, c[Pro-Arg-Phe-Phe-Dap-Ala-Phe-DPro], Mimetic of Agouti-Related Protein(87-132) [AGRP(87-132)] with Equipotent Mouse Melanocortin-4 Receptor (mMC4R) Antagonist Pharmacology.Synthetic mimetics of protein secondary structure domainsA Peptidomimetic Antibiotic Targets Outer Membrane Proteins and Disrupts Selectively the Outer Membrane in Escherichia coli.Conformation-dependent recognition of HIV gp120 by designed ankyrin repeat proteins provides access to novel HIV entry inhibitors.Functional consequences of retro-inverso isomerization of a miniature protein inhibitor of the p53-MDM2 interaction.Artificial beta-sheets: chemical models of beta-sheets.Structural properties of non-traditional drug targets present new challenges for virtual screening.Diversity of Secondary Structure in Catalytic Peptides with β-Turn-Biased SequencesPeptide and peptidomimetic ligands for CXC chemokine receptor 4 (CXCR4).New Modalities for Challenging Targets in Drug Discovery.Modulating protein-protein interactions: the potential of peptides.Construction of peptoids with all trans-amide backbones and peptoid reverse turns via the tactical incorporation of N-aryl side chains capable of hydrogen bondingLight-Switchable Peptides with a Hemithioindigo Unit: Peptide Design, Photochromism, and Optical Spectroscopy.Flexibility is important for inhibition of the MDM2/p53 protein-protein interaction by cyclic β-hairpins.Rational Design of Nanobody80 Loop Peptidomimetics: Towards Biased β2 Adrenergic Receptor Ligands.Guided folding takes a start from the molecular imprinting of structured epitopes.Systematic Targeting of Protein-Protein InteractionsPeptide N-Amination Supports β-Sheet Conformations.Macrocycles: lessons from the distant past, recent developments, and future directions.Hapivirins and diprovirins: novel θ-defensin analogs with potent activity against influenza A virus.
P2860
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P2860
Beta-hairpin peptidomimetics: design, structures and biological activities.
description
2008 nî lūn-bûn
@nan
2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Beta-hairpin peptidomimetics: design, structures and biological activities.
@ast
Beta-hairpin peptidomimetics: design, structures and biological activities.
@en
type
label
Beta-hairpin peptidomimetics: design, structures and biological activities.
@ast
Beta-hairpin peptidomimetics: design, structures and biological activities.
@en
prefLabel
Beta-hairpin peptidomimetics: design, structures and biological activities.
@ast
Beta-hairpin peptidomimetics: design, structures and biological activities.
@en
P356
P1476
Beta-hairpin peptidomimetics: design, structures and biological activities.
@en
P2093
John A Robinson
P304
P356
10.1021/AR700259K
P407
P577
2008-04-16T00:00:00Z