O-Glucuronidation of the lung carcinogen 4-(methylnitrosamino)-1- (3-pyridyl)-1-butanol (NNAL) by human UDP-glucuronosyltransferases 2B7 and 1A9.
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Nicotine chemistry, metabolism, kinetics and biomarkersContributions of human enzymes in carcinogen metabolismMeta-analysis reveals a lack of association between UGT2B17 deletion polymorphism and tumor susceptibility.UDP-glucuronosyltransferase 1A10: activity against the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, and a potential role for a novel UGT1A10 promoter deletion polymorphism in cancer susceptibility.Characterization of raloxifene glucuronidation: potential role of UGT1A8 genotype on raloxifene metabolism in vivo.Lack of association between UGT1A7, UGT1A9, ARP, SPINK1 and CFTR gene polymorphisms and pancreatic cancer in Italian patients.Characterization of UDP-glucuronosyltransferase 2A1 (UGT2A1) variants and their potential role in tobacco carcinogenesis.Correlation between bilirubin glucuronidation and estradiol-3-gluronidation in the presence of model UDP-glucuronosyltransferase 1A1 substrates/inhibitors.Potential role of UGT pharmacogenetics in cancer treatment and prevention: focus on tamoxifen and aromatase inhibitors.UGT1A and UGT2B genetic variation alters nicotine and nitrosamine glucuronidation in european and african american smokers.Characterization of dibenzo[a,l]pyrene-trans-11,12-diol (dibenzo[def,p]chrysene) glucuronidation by UDP-glucuronosyltransferases.Phenylbutyl isoselenocyanate modulates phase I and II enzymes and inhibits 4-(methylnitrosamino)-1-(3-pyridyl)- 1-butanone-induced DNA adducts in mice.Glucuronidation of trans-3'-hydroxycotinine by UGT2B17 and UGT2B10.Identification and functional characterization of a novel UDP-glucuronosyltransferase 2A1 splice variant: potential importance in tobacco-related cancer susceptibility.Cloning of UGT1A9 cDNA from liver tissues and its expression in CHL cells.Importance of UDP-glucuronosyltransferases 2A2 and 2A3 in tobacco carcinogen metabolism.Effects of menthol on tobacco smoke exposure, nicotine dependence, and NNAL glucuronidation.Functional significance of UDP-glucuronosyltransferase variants in the metabolism of active tamoxifen metabolitesPotential role of UGT pharmacogenetics in cancer treatment and prevention: focus on tamoxifen.High throughput liquid and gas chromatography-tandem mass spectrometry assays for tobacco-specific nitrosamine and polycyclic aromatic hydrocarbon metabolites associated with lung cancer in smokers.Glucuronidation of tobacco-specific nitrosamines by UGT2B10Association between Glucuronidation Genotypes and Urinary NNAL Metabolic Phenotypes in Smokers.Functional characterization of low-prevalence missense polymorphisms in the UDP-glucuronosyltransferase 1A9 gene.Exposure to the carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in smokers from 3 populations with different risks of lung cancer.Exposure and Metabolic Activation Biomarkers of Carcinogenic Tobacco-Specific Nitrosamines.UGT2B gene expression analysis in multiple tobacco carcinogen-targeted tissues.Characterization of UGTs active against SAHA and association between SAHA glucuronidation activity phenotype with UGT genotype.Clinical and biochemical studies support smokeless tobacco's carcinogenic potential in the human oral cavity.A new liquid chromatography/mass spectrometry method for 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in urine.Influence of UGT2B10 genotype on urinary excretion of NNAL-N-glucuronide by African American smokers.
P2860
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P2860
O-Glucuronidation of the lung carcinogen 4-(methylnitrosamino)-1- (3-pyridyl)-1-butanol (NNAL) by human UDP-glucuronosyltransferases 2B7 and 1A9.
description
2000 nî lūn-bûn
@nan
2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
O-Glucuronidation of the lung ...... nosyltransferases 2B7 and 1A9.
@ast
O-Glucuronidation of the lung ...... nosyltransferases 2B7 and 1A9.
@en
type
label
O-Glucuronidation of the lung ...... nosyltransferases 2B7 and 1A9.
@ast
O-Glucuronidation of the lung ...... nosyltransferases 2B7 and 1A9.
@en
prefLabel
O-Glucuronidation of the lung ...... nosyltransferases 2B7 and 1A9.
@ast
O-Glucuronidation of the lung ...... nosyltransferases 2B7 and 1A9.
@en
P2093
P1476
O-Glucuronidation of the lung ...... onosyltransferases 2B7 and 1A9
@en
P2093
P304
P577
2000-11-01T00:00:00Z