The intrinsically unstable life of DNA triplet repeats associated with human hereditary disorders.
about
Length-dependent energetics of (CTG)n and (CAG)n trinucleotide repeats.Advances in mechanisms of genetic instability related to hereditary neurological diseases.Crystal structure of actinomycin D bound to the CTG triplet repeat sequences linked to neurological diseasesThe Siblings With Ischemic Stroke Study (SWISS): a progress report.Mouse models of Huntington's disease and methodological considerations for therapeutic trials.An orthogonal oligonucleotide protecting group strategy that enables assembly of repetitive or highly structured DNAs.Human XPA and RPA DNA repair proteins participate in specific recognition of triplex-induced helical distortionsExpansion of tandem repeats in sea anemone Nematostella vectensis proteome: A source for gene novelty?Linear plasmid vector for cloning of repetitive or unstable sequences in Escherichia coliA malaria vaccine based on the polymorphic block 2 region of MSP-1 that elicits a broad serotype-spanning immune responseEfficient generation of recombinant influenza A viruses employing a new approach to overcome the genetic instability of HA segments.RNA structure of trinucleotide repeats associated with human neurological diseases.Long CTG tracts from the myotonic dystrophy gene induce deletions and rearrangements during recombination at the APRT locus in CHO cells.Double-strand breaks in the myotonic dystrophy type 1 and the fragile X syndrome triplet repeat sequences induce different types of mutations in DNA flanking sequences in Escherichia coli.Structures of trinucleotide repeats in human transcripts and their functional implications.Non-B DNA conformations, genomic rearrangements, and human disease.The stacked-X DNA Holliday junction and protein recognition.Repair of DNA double-strand breaks within the (GAA*TTC)n sequence results in frequent deletion of the triplet-repeat sequenceReplication fork stalling at natural impediments.DNA energy landscapes via calorimetric detection of microstate ensembles of metastable macrostates and triplet repeat diseasesRepeat expansion by homologous recombination in the mouse germ line at palindromic sequences.Discovery of the role of non-B DNA structures in mutagenesis and human genomic disorders.Methods to determine DNA structural alterations and genetic instability.Role of TLS DNA polymerases eta and kappa in processing naturally occurring structured DNA in human cellsTranscription influences the types of deletion and expansion products in an orientation-dependent manner from GAC*GTC repeatsNaturally occurring H-DNA-forming sequences are mutagenic in mammalian cells.Breakpoints of gross deletions coincide with non-B DNA conformations.The yin and yang of repair mechanisms in DNA structure-induced genetic instability.Recognition of Local DNA Structures by p53 Protein.Effects of Replication and Transcription on DNA Structure-Related Genetic InstabilityExtrahelical cytosine bases in DNA duplexes containing d[GCC](n).d[GCC](n) repeats: detection by a mechlorethamine crosslinking reaction.Slipped-strand DNAs formed by long (CAG)*(CTG) repeats: slipped-out repeats and slip-out junctions.Selectable system for monitoring the instability of CTG/CAG triplet repeats in mammalian cells.Replication-mediated instability of the GAA triplet repeat mutation in Friedreich ataxia.Replication stalling at Friedreich's ataxia (GAA)n repeats in vivo.Intracellular transcription of G-rich DNAs induces formation of G-loops, novel structures containing G4 DNADNA expansions generated by human Polμ on iterative sequences.Energetic coupling between clustered lesions modulated by intervening triplet repeat bulge loops: allosteric implications for DNA repair and triplet repeat expansion.DNA repair and DNA triplet repeat expansion: the impact of abasic lesions on triplet repeat DNA energetics.The role of nucleotide cofactor binding in cooperativity and specificity of MutS recognition.
P2860
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P2860
The intrinsically unstable life of DNA triplet repeats associated with human hereditary disorders.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The intrinsically unstable lif ...... th human hereditary disorders.
@ast
The intrinsically unstable lif ...... th human hereditary disorders.
@en
type
label
The intrinsically unstable lif ...... th human hereditary disorders.
@ast
The intrinsically unstable lif ...... th human hereditary disorders.
@en
prefLabel
The intrinsically unstable lif ...... th human hereditary disorders.
@ast
The intrinsically unstable lif ...... th human hereditary disorders.
@en
P1476
The intrinsically unstable lif ...... th human hereditary disorders.
@en
P2093
P304
P356
10.1016/S0079-6603(00)66029-4
P577
2001-01-01T00:00:00Z