Adenosine analogues as inhibitors of Trypanosoma brucei phosphoglycerate kinase: elucidation of a novel binding mode for a 2-amino-N(6)-substituted adenosine.
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Kinases as druggable targets in trypanosomatid protozoan parasitesThe Role of Medical Structural Genomics in Discovering New Drugs for Infectious DiseasesX-ray structures of the three Lactococcus lactis dihydroxyacetone kinase subunits and of a transient intersubunit complexRibose 5-phosphate isomerase B knockdown compromises Trypanosoma brucei bloodstream form infectivityVirtual screening of combinatorial libraries across a gene family: in search of inhibitors of Giardia lamblia guanine phosphoribosyltransferase.Synthesis of nucleoside libraries on solid support. I. N2,N6-disubstituted diaminopurine nucleosides.2,N6-disubstituted adenosine analogs with antitrypanosomal and antimalarial activities.Dissecting interactions between nucleosides and germination receptors in Bacillus cereus 569 spores.Homology modeling and molecular dynamics study of NAD-dependent glycerol-3-phosphate dehydrogenase from Trypanosoma brucei rhodesiense, a potential target enzyme for anti-sleeping sickness drug development.Polymer-assisted structural modification on nucleosides and nucleotides.Glycolysis in the african trypanosome: targeting enzymes and their subcellular compartments for therapeutic developmentThree-dimensional structures in the design of therapeutics targeting parasitic protozoa: reflections on the past, present and future.Dissecting Leishmania infantum Energy Metabolism - A Systems Perspective.Synthesis, biological evaluation and molecular modeling studies of N6-benzyladenosine analogues as potential anti-toxoplasma agents.Purine and pyrimidine transport in pathogenic protozoa: from biology to therapy.Anticancer agents that counteract tumor glycolysis.Estrogen Receptor Ligands: A Review (2013-2015).Translocation of solutes and proteins across the glycosomal membrane of trypanosomes; possibilities and limitations for targeting with trypanocidal drugs.Kinetin Riboside and Its ProTides Activate the Parkinson's Disease Associated PTEN-Induced Putative Kinase 1 (PINK1) Independent of Mitochondrial DepolarizationFunctionalization of guanosine and 2'-deoxyguanosine at C6: a modified Appel process and S(N)Ar displacement of imidazole.Scaffold Repurposing of Nucleosides (Adenosine Receptor Agonists): Enhanced Activity at the Human Dopamine and Norepinephrine Sodium Symporters.Supramolecular hydrogen-bonding patterns in two cocrystals of the N(7)-H tautomeric form of N(6)-benzoyladenine: N(6)-benzoyladenine-3-hydroxypyridinium-2-carboxylate (1/1) and N(6)-benzoyladenine-DL-tartaric acid (1/1).
P2860
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P2860
Adenosine analogues as inhibitors of Trypanosoma brucei phosphoglycerate kinase: elucidation of a novel binding mode for a 2-amino-N(6)-substituted adenosine.
description
2000 nî lūn-bûn
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2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
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2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
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2000年论文
@wuu
name
Adenosine analogues as inhibit ...... no-N(6)-substituted adenosine.
@ast
Adenosine analogues as inhibit ...... no-N(6)-substituted adenosine.
@en
type
label
Adenosine analogues as inhibit ...... no-N(6)-substituted adenosine.
@ast
Adenosine analogues as inhibit ...... no-N(6)-substituted adenosine.
@en
prefLabel
Adenosine analogues as inhibit ...... no-N(6)-substituted adenosine.
@ast
Adenosine analogues as inhibit ...... no-N(6)-substituted adenosine.
@en
P2093
P356
P1476
Adenosine analogues as inhibit ...... no-N(6)-substituted adenosine.
@en
P2093
Buckner FS
Van Voorhis WC
Verlinde CL
P304
P356
10.1021/JM000287A
P407
P577
2000-11-01T00:00:00Z