6-Alkylamino- and 2,3-dihydro-3'-methoxy-2-phenyl-4-quinazolinones and related compounds: their synthesis, cytotoxicity, and inhibition of tubulin polymerization.
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Novel quinazolinone MJ-29 triggers endoplasmic reticulum stress and intrinsic apoptosis in murine leukemia WEHI-3 cells and inhibits leukemic miceAsymmetric synthesis of 2,3-dihydro-2-arylquinazolin-4-ones: methodology and application to a potent fluorescent tubulin inhibitor with anticancer activity.Aggravated DNA damage as a basis for enhanced glioma cell killing by MJ-66 in combination with minocycline.Interactions of antimitotic peptides and depsipeptides with tubulin.Common pharmacophore of structurally distinct small-molecule inhibitors of intracellular retrograde trafficking of ribosome inactivating proteins.MJ-66 induces malignant glioma cells G2/M phase arrest and mitotic catastrophe through regulation of cyclin B1/Cdk1 complex.Design and synthesis of new 2-arylnaphthyridin-4-ones as potent antitumor agents targeting tumorigenic cell lines.A novel microtubule inhibitor, MT3-037, causes cancer cell apoptosis by inducing mitotic arrest and interfering with microtubule dynamics.Molecular modelling, synthesis, cytotoxicity and anti-tumour mechanisms of 2-aryl-6-substituted quinazolinones as dual-targeted anti-cancer agents.Synthesis, Biological Evaluation and Docking Analysis of Some Novel Quinazolin Derivatives as Antitumor Agents.Design and synthesis of 2-(3-benzo[b]thienyl)-6,7-methylenedioxyquinolin-4-one analogues as potent antitumor agents that inhibit tubulin assemblySingle-Round Infectious Particle Antiviral Screening Assays for the Japanese Encephalitis Virus.Endophytic Actinobacteria from the Brazilian Medicinal Plant Lychnophora ericoides Mart. and the Biological Potential of Their Secondary Metabolites.Computer-aided design, synthesis and validation of 2-phenylquinazolinone fragments as CDK9 inhibitors with anti-HIV-1 Tat-mediated transcription activity.6',7'-Dimeth-oxy-1',2'-dihydro-spiro-[cyclo-hexane-1,2'-quinazolin]-4'(3'H)-one.Structure-based design, synthesis and crystallization of 2-arylquinazolines as lipid pocket ligands of p38α MAPK.Synthesis and antihypertensive screening of new derivatives of quinazolines linked with isoxazole.Biological effects of a new set 1,2,4-triazolo[1,5-a]quinazolines on heart rate and blood pressure.Cytotoxic Activity and Three-Dimensional Quantitative Structure Activity Relationship of 2-Aryl-1,8-naphthyridin-4-ones.Synthesis and characterization of quinazoline derivatives: search for hybrid molecule as diuretic and antihypertensive agents.Effect of DNA damage response by quinazolinone analogue HMJ-38 on human umbilical vein endothelial cells: evidence for γH2A.X and DNA-PK-dependent pathway.Transition-metal-catalyst-free synthesis of anthranilic acid derivatives by transfer hydrogenative coupling of 2-nitroaryl methanols with alcohols/amines.Synthesis and photophysical properties of the 2-(3-(2-Alkyl-6,8-diaryl-4-oxo-1,2,3,4-tetrahydroquinazolin-2-yl)propyl)-6,8-diarylquinazolin-4(3H)-ones.Enantioselective synthesis of dihydroquinazolinone derivatives catalyzed by a chiral organocatalystSynthesis of Bis-2,3-dihydroquinazolin-4(1H)-ones and 2,3-Dihydroquinazolin-4(1H)-ones Derivatives with the Aid of Silica-Supported Preyssler Nanoparticles
P2860
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P2860
6-Alkylamino- and 2,3-dihydro-3'-methoxy-2-phenyl-4-quinazolinones and related compounds: their synthesis, cytotoxicity, and inhibition of tubulin polymerization.
description
2000 nî lūn-bûn
@nan
2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
6-Alkylamino- and 2,3-dihydro- ...... ion of tubulin polymerization.
@ast
6-Alkylamino- and 2,3-dihydro- ...... ion of tubulin polymerization.
@en
type
label
6-Alkylamino- and 2,3-dihydro- ...... ion of tubulin polymerization.
@ast
6-Alkylamino- and 2,3-dihydro- ...... ion of tubulin polymerization.
@en
prefLabel
6-Alkylamino- and 2,3-dihydro- ...... ion of tubulin polymerization.
@ast
6-Alkylamino- and 2,3-dihydro- ...... ion of tubulin polymerization.
@en
P2093
P356
P1476
6-Alkylamino- and 2,3-dihydro- ...... ion of tubulin polymerization.
@en
P2093
Nakanishi Y
P304
P356
10.1021/JM000151C
P407
P577
2000-11-01T00:00:00Z