Impaired membrane traffic in defective ether lipid biosynthesis.
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Posttranslational regulation of fatty acyl-CoA reductase 1, Far1, controls ether glycerophospholipid synthesisMass spectrometric analysis reveals changes in phospholipid, neutral sphingolipid and sulfatide molecular species in progressive epilepsy with mental retardation, EPMR, brain: a case studyPeroxisomes in brain development and functionExogenous ether lipids predominantly target mitochondriaPrecursor of ether phospholipids is synthesized by a flavoenzyme through covalent catalysisDefects in myelination, paranode organization and Purkinje cell innervation in the ether lipid-deficient mouse cerebellumInactivation of ether lipid biosynthesis causes male infertility, defects in eye development and optic nerve hypoplasia in miceExome sequencing in HFE C282Y homozygous men with extreme phenotypes identifies a GNPAT variant associated with severe iron overload.Homeostasis of phospholipids - The level of phosphatidylethanolamine tightly adapts to changes in ethanolamine plasmalogens.Detection of molecular paths associated with insulitis and type 1 diabetes in non-obese diabetic mouseMouse brain plasmalogens are targets for hypochlorous acid-mediated modification in vitro and in vivo.Plasmalogen synthesis is regulated via alkyl-dihydroxyacetonephosphate-synthase by amyloid precursor protein processing and is affected in Alzheimer's disease.Glycerophosphate/Acylglycerophosphate acyltransferases.Blind sterile 2 (bs2), a hypomorphic mutation in Agps, results in cataracts and male sterility in mice.The ether lipid precursor hexadecylglycerol stimulates the release and changes the composition of exosomes derived from PC-3 cells.Long-term increased carnitine palmitoyltransferase 1A expression in ventromedial hypotalamus causes hyperphagia and alters the hypothalamic lipidomic profileIn vitro and in vivo plasmalogen replacement evaluations in rhizomelic chrondrodysplasia punctata and Pelizaeus-Merzbacher disease using PPI-1011, an ether lipid plasmalogen precursorEarly lipid changes in acute kidney injury using SWATH lipidomics coupled with MALDI tissue imaging.Functional group selective derivatization and gas-phase fragmentation reactions of plasmalogen glycerophospholipids.Caveolin-1-dependent and -independent membrane domainsLeishmania dihydroxyacetonephosphate acyltransferase LmDAT is important for ether lipid biosynthesis but not for the integrity of detergent resistant membranes.The biophysical properties of plasmalogens originating from their unique molecular architecture.Determination of cell uptake pathways for tumor inhibitor lysyl oxidase propeptide.Mild reduction of plasmalogens causes rhizomelic chondrodysplasia punctata: functional characterization of a novel mutation.Defective lipid remodeling of GPI anchors in peroxisomal disorders, Zellweger syndrome, and rhizomelic chondrodysplasia punctata.Plasmalogen homeostasis - regulation of plasmalogen biosynthesis and its physiological consequence in mammals.Functional characterization of novel mutations in GNPAT and AGPS, causing rhizomelic chondrodysplasia punctata (RCDP) types 2 and 3.Peroxisomal dysfunctions cause lysosomal storage and axonal Kv1 channel redistribution in peripheral neuropathy.GNPAT p.D519G is independently associated with markedly increased iron stores in HFE p.C282Y homozygotes.Deficiency in ethanolamine plasmalogen leads to altered cholesterol transport.The Trypanosoma brucei dihydroxyacetonephosphate acyltransferase TbDAT is dispensable for normal growth but important for synthesis of ether glycerophospholipids.Plasmalogen biosynthesis is spatiotemporally regulated by sensing plasmalogens in the inner leaflet of plasma membranes.Impaired neurotransmission in ether lipid-deficient nerve terminalsDysregulation of Plasmalogen Homeostasis Impairs Cholesterol Biosynthesis.Ether phospholipids and glycosylinositolphospholipids are not required for amastigote virulence or for inhibition of macrophage activation by Leishmania major.Protective role of endogenous plasmalogens against hepatic steatosis and steatohepatitis in mice.Reduced muscle strength in ether lipid-deficient mice is accompanied by altered development and function of the neuromuscular junction.Extracellular vesicles released by fibroblasts undergoing H-Ras induced senescence show changes in lipid profile.Glyceronephosphate O-acyltransferase as a hemochromatosis modifier gene: Another iron in the fire?From peroxisomal disorders to common neurodegenerative diseases - the role of ether phospholipids in the nervous system.
P2860
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P2860
Impaired membrane traffic in defective ether lipid biosynthesis.
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Impaired membrane traffic in defective ether lipid biosynthesis.
@ast
Impaired membrane traffic in defective ether lipid biosynthesis.
@en
type
label
Impaired membrane traffic in defective ether lipid biosynthesis.
@ast
Impaired membrane traffic in defective ether lipid biosynthesis.
@en
prefLabel
Impaired membrane traffic in defective ether lipid biosynthesis.
@ast
Impaired membrane traffic in defective ether lipid biosynthesis.
@en
P2093
P356
P1476
Impaired membrane traffic in defective ether lipid biosynthesis.
@en
P2093
Hunziker A
P304
P356
10.1093/HMG/10.2.127
P577
2001-01-01T00:00:00Z