Depletion of intracellular zinc and copper with TPEN results in apoptosis of cultured human retinal pigment epithelial cells.
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PAC-1 activates procaspase-3 in vitro through relief of zinc-mediated inhibitionCellular Zn depletion by metal ion chelators (TPEN, DTPA and chelex resin) and its application to osteoblastic MC3T3-E1 cells.Human RPE cell apoptosis induced by activated monocytes is mediated by caspase-3 activation.Copper chelation selectively kills colon cancer cells through redox cycling and generation of reactive oxygen speciesDeficiency of calcium and magnesium induces apoptosis via scavenger receptor BITranscriptional response of Escherichia coli to TPEN.Quantitative imaging of mitochondrial and cytosolic free zinc levels in an in vitro model of ischemia/reperfusion.Zinc Chelation Mediates the Lysosomal Disruption without Intracellular ROS Generation.Zinc chelation induces rapid depletion of the X-linked inhibitor of apoptosis and sensitizes prostate cancer cells to TRAIL-mediated apoptosis.Depletion of intracellular zinc increases expression of tumorigenic cytokines VEGF, IL-6 and IL-8 in prostate cancer cells via NF-kappaB-dependent pathwayTris(2-pyridylmethyl)amine (TPA) as a membrane-permeable chelator for interception of biological mobile zinc.Activation of the mitochondrial caspase pathway and subsequent calpain activation in monkey RPE cells cultured under zinc depletion.Prohibitin as an oxidative stress biomarker in the eyeNeuroprotective role of erythropoietin by antiapoptosis in the retina.Early biosignature of oxidative stress in the retinal pigment epithelium.Mobile zinc increases rapidly in the retina after optic nerve injury and regulates ganglion cell survival and optic nerve regeneration.Cytoprotection by endogenous zinc in the vertebrate retina.Review: Zinc's functional significance in the vertebrate retinaThe mucolipin-1 (TRPML1) ion channel, transmembrane-163 (TMEM163) protein, and lysosomal zinc handling.Administration of Zinc Chelators Improves Survival of Mice Infected with Aspergillus fumigatus both in Monotherapy and in Combination with Caspofungin.Zinc Protects Oxidative Stress-Induced RPE Death by Reducing Mitochondrial Damage and Preventing Lysosome Rupture.
P2860
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P2860
Depletion of intracellular zinc and copper with TPEN results in apoptosis of cultured human retinal pigment epithelial cells.
description
2001 nî lūn-bûn
@nan
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Depletion of intracellular zin ...... inal pigment epithelial cells.
@ast
Depletion of intracellular zin ...... inal pigment epithelial cells.
@en
type
label
Depletion of intracellular zin ...... inal pigment epithelial cells.
@ast
Depletion of intracellular zin ...... inal pigment epithelial cells.
@en
prefLabel
Depletion of intracellular zin ...... inal pigment epithelial cells.
@ast
Depletion of intracellular zin ...... inal pigment epithelial cells.
@en
P2093
P1476
Depletion of intracellular zin ...... inal pigment epithelial cells.
@en
P2093
P304
P407
P577
2001-02-01T00:00:00Z