The selective cyclooxygenase-2 inhibitor rofecoxib reduces kainate-induced cell death in the rat hippocampus.
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Expression and localization of cyclooxygenase-1 and -2 in human sporadic amyotrophic lateral sclerosisSelective COX-2 inhibition prevents progressive dopamine neuron degeneration in a rat model of Parkinson's diseaseCyclooxygenase-2 in epilepsy.Mitochondrial dysfunction and increased sensitivity to excitotoxicity in mice deficient in DNA mismatch repairInvolvement of PGE2 and PGDH but not COX-2 in thrombin-induced cortical neuron apoptosisRole of oxidative stress in epileptic seizures.Cytosolic phospholipase A2 alpha inhibition prevents neuronal NMDA receptor-stimulated arachidonic acid mobilization and prostaglandin production but not subsequent cell death.Ablation of cyclooxygenase-2 in forebrain neurons is neuroprotective and dampens brain inflammation after status epilepticusPostictal behavioural impairments are due to a severe prolonged hypoperfusion/hypoxia event that is COX-2 dependent.Cyclooxygenase-2-specific inhibitor improves functional outcomes, provides neuroprotection, and reduces inflammation in a rat model of traumatic brain injury.Co-administration of subtherapeutic diazepam enhances neuroprotective effect of COX-2 inhibitor, NS-398, after lithium pilocarpine-induced status epilepticus.Prophylactic, prandial rofecoxib treatment lacks efficacy against acute PTZ-induced seizure generation and kindling acquisition.COX-2 inhibitors as adjunctive therapy in schizophrenia.Reduction in delayed mortality and subtle improvement in retrograde memory performance in pilocarpine-treated mice with conditional neuronal deletion of cyclooxygenase-2 geneLipid signaling and synaptic plasticity.Effects of Peripheral and Intra-hippocampal Administration of Sodium Salicylate on Spatial Learning and Memory of Rats.Inhibition of the prostaglandin receptor EP2 following status epilepticus reduces delayed mortality and brain inflammation.Altered GABAergic neurotransmission is associated with increased kainate-induced seizure in prostaglandin-endoperoxide synthase-2 deficient miceDoes brain inflammation mediate pathological outcomes in epilepsy?Cyclooxygenase-2 inhibitor inhibits hippocampal synaptic reorganization in pilocarpine-induced status epilepticus rats.Antiinflammatory and neuroprotective actions of COX2 inhibitors in the injured brain.Microglial inhibition of neuroprotection by antagonists of the EP1 prostaglandin E2 receptorAnticonvulsant and hypnotic effects of amiodarone.Genetic disruption of cyclooxygenase-2 does not improve histological or behavioral outcome after traumatic brain injury in miceAnti-Inflammatory Small Molecules To Treat Seizures and Epilepsy: From Bench to BedsideDefining the therapeutic time window for suppressing the inflammatory prostaglandin E2 signaling after status epilepticus.Neuroinflammation, microglia and implications for anti-inflammatory treatment in Alzheimer's disease.Causes of CNS inflammation and potential targets for anticonvulsants.Expression changes in mouse brains following nicotine-induced seizures: the modulation of transcription factor networks.A COX/5-LOX Inhibitor Licofelone Revealed Anticonvulsant Properties Through iNOS Diminution in Mice.Anthocyanins protect against kainic acid-induced excitotoxicity and apoptosis via ROS-activated AMPK pathway in hippocampal neurons.Temporal profiles of age-dependent changes in cytokine mRNA expression and glial cell activation after status epilepticus in postnatal rat hippocampus.Endocannabinoid 2-arachidonoylglycerol protects neurons by limiting COX-2 elevation.Chronic lithium administration to rats selectively modifies 5-HT2A/2C receptor-mediated brain signaling via arachidonic acid.Effects of intraperitoneal injection of Rofecoxib in a mouse model of ALS.Age-dependent cyclooxygenase-2 induction and neuronal damage after status epilepticus in the postnatal rat hippocampus.Cyclooxygenase-2 expression and effect of celecoxib in flurothyl-induced neonatal seizure.A dual inhibitor of cyclooxygenase and 5-lipoxygenase protects against kainic acid-induced brain injury.Co-administration of acetyl-11-keto-beta-boswellic acid, a specific 5-lipoxygenase inhibitor, potentiates the protective effect of COX-2 inhibitors in kainic acid-induced neurotoxicity in mice.Profiling of eicosanoid production in the rat hippocampus during kainic acid-induced seizure: dual phase regulation and differential involvement of COX-1 and COX-2.
P2860
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P2860
The selective cyclooxygenase-2 inhibitor rofecoxib reduces kainate-induced cell death in the rat hippocampus.
description
2001 nî lūn-bûn
@nan
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The selective cyclooxygenase-2 ...... death in the rat hippocampus.
@ast
The selective cyclooxygenase-2 ...... death in the rat hippocampus.
@en
type
label
The selective cyclooxygenase-2 ...... death in the rat hippocampus.
@ast
The selective cyclooxygenase-2 ...... death in the rat hippocampus.
@en
prefLabel
The selective cyclooxygenase-2 ...... death in the rat hippocampus.
@ast
The selective cyclooxygenase-2 ...... death in the rat hippocampus.
@en
P2860
P1476
The selective cyclooxygenase-2 ...... death in the rat hippocampus.
@en
P2860
P304
P356
10.1046/J.1460-9568.2001.01420.X
P407
P577
2001-02-01T00:00:00Z