Ultraviolet irradiation activates PI 3-kinase/AKT survival pathway via EGF receptors in human skin in vivo.
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Main roads to melanomaAKT-dependent phosphorylation of Niban regulates nucleophosmin- and MDM2-mediated p53 stability and cell apoptosisDNA-dependent protein kinase catalytic subunit (DNA-PKcs)-SIN1 association mediates ultraviolet B (UVB)-induced Akt Ser-473 phosphorylation and skin cell survivalDifferential ErbB1 signaling in squamous cell versus basal cell carcinoma of the skinActivation of the PI3K/Akt/mTOR and MAPK Signaling Pathways in Response to Acute Solar-Simulated Light Exposure of Human Skin.A systems-biological study on the identification of safe and effective molecular targets for the reduction of ultraviolet B-induced skin pigmentationDual inhibition of both the epidermal growth factor receptor and erbB2 effectively inhibits the promotion of skin tumors during two-stage carcinogenesis.Functional protein pathway activation mapping of the progression of normal skin to squamous cell carcinomaCaffeic acid directly targets ERK1/2 to attenuate solar UV-induced skin carcinogenesis.Modulating the structure of EGFR with UV light: new possibilities in cancer therapy.SIRT1 confers protection against UVB- and H2O2-induced cell death via modulation of p53 and JNK in cultured skin keratinocytes.Protein kinases and transcription factors activation in response to UV-radiation of skin: implications for carcinogenesis.UV irradiation/cold shock-mediated apoptosis is switched to bubbling cell death at low temperaturesEGFR activation and ultraviolet light-induced skin carcinogenesis.Taxifolin suppresses UV-induced skin carcinogenesis by targeting EGFR and PI3K.RSK2 as a key regulator in human skin cancer.Inhibition of mTOR suppresses UVB-induced keratinocyte proliferation and survival.Niacin protects against UVB radiation-induced apoptosis in cultured human skin keratinocytesSunlight UV-induced skin cancer relies upon activation of the p38α signaling pathwayEGFR activation confers protections against UV-induced apoptosis in cultured mouse skin dendritic cells.Erbb2 suppresses DNA damage-induced checkpoint activation and UV-induced mouse skin tumorigenesis.The research on lapatinib in autophagy, cell cycle arrest and epithelial to mesenchymal transition via Wnt/ErK/PI3K-AKT signaling pathway in human cutaneous squamous cell carcinoma.New Enlightenment of Skin Cancer Chemoprevention through Phytochemicals: In Vitro and In Vivo Studies and the Underlying MechanismsThe role of AKT/mTOR pathway in stress response to UV-irradiation: implication in skin carcinogenesis by regulation of apoptosis, autophagy and senescenceSIRT1 regulates MAPK pathways in vitiligo skin: insight into the molecular pathways of cell survivalNegative regulation of the FOXO3a transcription factor by mTORC2 induces a pro-survival response following exposure to ultraviolet-B irradiation.Molecular signaling cascades involved in nonmelanoma skin carcinogenesis.Soluble E-cadherin: a critical oncogene modulating receptor tyrosine kinases, MAPK and PI3K/Akt/mTOR signaling.Mechanisms of skin aging induced by EGFR inhibitors.AMP-activated protein kinase contributes to UV- and H2O2-induced apoptosis in human skin keratinocytesInduction of Tyrosine Phosphorylation of UV-Activated EGFR by the Beta-Human Papillomavirus Type 8 E6 Leads to Papillomatosis.Molecular Insights into the Interaction of RONS and Thieno[3,2-c]pyran Analogs with SIRT6/COX-2: A Molecular Dynamics Study.
P2860
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P2860
Ultraviolet irradiation activates PI 3-kinase/AKT survival pathway via EGF receptors in human skin in vivo.
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Ultraviolet irradiation activa ...... ceptors in human skin in vivo.
@ast
Ultraviolet irradiation activa ...... ceptors in human skin in vivo.
@en
type
label
Ultraviolet irradiation activa ...... ceptors in human skin in vivo.
@ast
Ultraviolet irradiation activa ...... ceptors in human skin in vivo.
@en
prefLabel
Ultraviolet irradiation activa ...... ceptors in human skin in vivo.
@ast
Ultraviolet irradiation activa ...... ceptors in human skin in vivo.
@en
P2093
P356
P1476
Ultraviolet irradiation activa ...... eceptors in human skin in vivo
@en
P2093
P304
P356
10.3892/IJO.18.3.461
P577
2001-03-01T00:00:00Z