Analysis of an activator:coactivator complex reveals an essential role for secondary structure in transcriptional activation.
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Dual roles of p300 in chromatin assembly and transcriptional activation in cooperation with nucleosome assembly protein 1 in vitro.Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1)Intrinsically disordered proteins in a physics-based worldNMDA-mediated and self-induced bdnf exon IV transcriptions are differentially regulated in cultured cortical neuronsCalmodulin kinase II attenuation of gene transcription by preventing cAMP response element-binding protein (CREB) dimerization and binding of the CREB-binding protein.Binding Mechanisms of Intrinsically Disordered Proteins: Theory, Simulation, and ExperimentMRG1 binds to the LIM domain of Lhx2 and may function as a coactivator to stimulate glycoprotein hormone alpha-subunit gene expressionRoles of phosphorylation and helix propensity in the binding of the KIX domain of CREB-binding protein by constitutive (c-Myb) and inducible (CREB) activatorsCooperativity in transcription factor binding to the coactivator CREB-binding protein (CBP). The mixed lineage leukemia protein (MLL) activation domain binds to an allosteric site on the KIX domainCa2+/cAMP response element-binding protein (CREB)-dependent activation of Per1 is required for light-induced signaling in the suprachiasmatic nucleus circadian clockNerve growth factor receptor signaling induces histone acetyltransferase domain-dependent nuclear translocation of p300/CREB-binding protein-associated factor and hGCN5 acetyltransferasesPoint mutation in the gene encoding p300 suppresses thrombocytopenia in Mpl-/- miceAnalysis of a cAMP regulated coactivator family reveals an alternative phosphorylation motif for AMPK family members.Phospho-SXXE/D motif mediated TNF receptor 1-TRADD death domain complex formation for T cell activation and migration.Molecular recognition of protein surfaces: high affinity ligands for the CBP KIX domain.Identification of small-molecule antagonists that inhibit an activator: coactivator interaction.Minimal activators that bind to the KIX domain of p300/CBP identified by phage display screening.Artificial transcriptional activation domains.Binding-induced folding of a natively unstructured transcription factor.Site-specific phosphorylation induces functionally active conformation in the intrinsically disordered N-terminal activation function (AF1) domain of the glucocorticoid receptor.Glucose regulates steady-state levels of PDX1 via the reciprocal actions of GSK3 and AKT kinasesp300 and CBP: partners for life and death.Saccharomyces cerevisiae Esc2p interacts with Sir2p through a small ubiquitin-like modifier (SUMO)-binding motif and regulates transcriptionally silent chromatin in a locus-dependent manner.Distinct effects of cAMP and mitogenic signals on CREB-binding protein recruitment impart specificity to target gene activation via CREB.Calcium regulation of neuronal gene expressionRole of secondary structure in discrimination between constitutive and inducible activators.Chromatin-dependent cooperativity between constitutive and inducible activation domains in CREB.CRTC1/MAML2 gain-of-function interactions with MYC create a gene signature predictive of cancers with CREB-MYC involvement.Dissecting allosteric effects of activator-coactivator complexes using a covalent small molecule ligand.CREB and the CRTC co-activators: sensors for hormonal and metabolic signalsMolecular recognition by the KIX domain and its role in gene regulation.Cryptochrome 1 regulates the circadian clock through dynamic interactions with the BMAL1 C terminus.Mechanisms of specificity in neuronal activity-regulated gene transcriptionTranscriptional coactivator PC4 stimulates promoter escape and facilitates transcriptional synergy by GAL4-VP16Role of transcription factor modifications in the pathogenesis of insulin resistance.A transcription factor-binding domain of the coactivator CBP is essential for long-term memory and the expression of specific target genes.PP2B-mediated dephosphorylation of c-Jun C terminus regulates phorbol ester-induced c-Jun/Sp1 interaction in A431 cells.Phosphorylation of the cyclic AMP response element binding protein mediates transforming growth factor beta-induced downregulation of cyclin A in vascular smooth muscle cellsRegulation of brain-derived neurotrophic factor expression in neurons.RGS13 acts as a nuclear repressor of CREB.
P2860
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P2860
Analysis of an activator:coactivator complex reveals an essential role for secondary structure in transcriptional activation.
description
1998 nî lūn-bûn
@nan
1998 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Analysis of an activator:coact ...... in transcriptional activation.
@ast
Analysis of an activator:coact ...... in transcriptional activation.
@en
type
label
Analysis of an activator:coact ...... in transcriptional activation.
@ast
Analysis of an activator:coact ...... in transcriptional activation.
@en
prefLabel
Analysis of an activator:coact ...... in transcriptional activation.
@ast
Analysis of an activator:coact ...... in transcriptional activation.
@en
P2093
P1433
P1476
Analysis of an activator:coact ...... in transcriptional activation.
@en
P2093
Montminy M
Radhakrishnan I
Shulman AI
P304
P356
10.1016/S1097-2765(00)80279-8
P577
1998-09-01T00:00:00Z